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Your search keyword '"Blancho Gilles"' showing total 10 results
Start Over Author "Blancho Gilles" Journal american journal of transplantation
10 results on '"Blancho Gilles"'

1. Preformed T cell alloimmunity and HLA eplet mismatch to guide immunosuppression minimization with tacrolimus monotherapy in kidney transplantation: Results of the CELLIMIN trial

Author

Bestard, Oriol, Meneghini, Maria, Crespo, Elena, Bemelman, Frederike, Koch, Martina, Volk, Hans D., Viklicky, Ondrej, Giral, Magali, Banas, Bernhard, Ruiz, Juan C., Melilli, Edoardo, Hu, Liu, van Duivenvoorden, Raphael, Nashan, Björn, Thaiss, Friedrich, Otto, Natalie M., Bold, Gantuja, Stein, Maik, Sefrin, Anett, Lachmann, Nils, Hruba, Petra, Stranavova, Lucia, Brouard, Sophie, Braudeau, Cécile, Blancho, Gilles, Banas, Miriam, Irure, Juan, Christakoudi, Sophia, Sanchez-Fueyo, Alberto, Wood, Kathryn J., Reinke, Petra, and Grinyó, Josep M.

Published
2021
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2. Tacrolimus- versus sirolimus-based immunosuppression after simultaneous pancreas and kidney transplantation: 5-year results of a randomized trial

Author

Cantarovich, Diego, Kervella, Delphine, Karam, Georges, Dantal, Jacques, Blancho, Gilles, Giral, Magali, Garandeau, Claire, Houzet, Aurélie, Ville, Simon, Branchereau, Julien, Delbos, Florent, Guillot-Gueguen, Cécile, Volteau, Christelle, Leroy, Maxime, Renaudin, Karine, Soulillou, Jean-Paul, and Hourmant, Maryvonne

Published
2020
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5. Feasibility, long-term safety, and immune monitoring of regulatory T cell therapy in living donor kidney transplant recipients

Author

Harden, Paul N., Game, David S., Sawitzki, Birgit, Van der Net, Jeroen B., Hester, Joanna, Bushell, Andrew, Issa, Fadi, Brook, Matthew O., Alzhrani, Alaa, Schlickeiser, Stephan, Scotta, Cristiano, Petchey, William, Streitz, Mathias, Blancho, Gilles, Tang, Quizhi, Markmann, James, Lechler, Robert I., Roberts, Ian S.D., Friend, Peter J., Hilton, Rachel, Geissler, Edward K., Wood, Kathryn J., and Lombardi, Giovanna

Published
2021
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6. Is COVID-19 infection more severe in kidney transplant recipients?

Author

Caillard, Sophie, Chavarot, Nathalie, Francois, Hélène, Matignon, Marie, Greze, Clarisse, Kamar, Nassim, Gatault, Philippe, Thaunat, Olivier, Legris, Tristan, Frimat, Luc, Westeel, Pierre F., Goutaudier, Valentin, Jdidou, Mariam, Snanoudj, Renaud, Colosio, Charlotte, Sicard, Antoine, Bertrand, Dominique, Mousson, Christiane, Bamoulid, Jamal, Masset, Christophe, Thierry, Antoine, Couzi, Lionel, Chemouny, Jonathan M., Duveau, Agnes, Moal, Valerie, Blancho, Gilles, Grimbert, Philippe, Durrbach, Antoine, Moulin, Bruno, Anglicheau, Dany, Ruch, Yvon, Kaeuffer, Charlotte, Benotmane, Ilies, Solis, Morgane, LeMeur, Yannick, Hazzan, Marc, and Danion, Francois

Published
2021
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10. Unique and specific Proteobacteriadiversity in urinary microbiota of tolerant kidney transplanted recipients

Author

Colas, Luc, Mongodin, Emmanuel F., Montassier, Emmanuel, Chesneau, Mélanie, Guerif, Pierrick, Hittle, Lauren, Giral, Magali, Bromberg, Jonathan S., Brouard, Sophie, Blancho, Gilles, Branchereau, Julien, Cantarovich, Diego, Cesbron, Anne, Chapelet, Agnès, Dantal, Jacques, Delbos, Florent, Deltombe, Clément, Devis, Anne, Figueres, Lucile, Garandeau, Claire, Gourraud‐Vercel, Caroline, Hourmant, Maryvonne, Kandell, Christine, Karam, Georges, Kerleau, Clarisse, Meurette, Aurélie, Moreau, Anne, Renaudin, Karine, Ville, Simon, and Walencik, Alexandre

Abstract

Host‐microbiota interactions can modulate the immune system both at local and systemic levels, with potential consequences for organ transplantation outcomes. In this study, we hypothesized that differences in the urinary microbiome following kidney transplantation would be associated with posttransplantation status: stable, minimally immunosuppressed, or tolerant. One hundred thirteen urine samples from stable (n = 51), minimally immunosuppressed (n = 19), and spontaneously tolerant (n = 16) patients, paired with age‐matched controls (n = 27) were profiled and compared to each other at a taxonomic level with special interest in the immunosuppressive regimen. All comparisons and correlations were adjusted on sex and time posttransplantation. Our results highlighted a unique and specific urinary microbiota associated with spontaneous tolerance characterized by a high diversity and a clear Proteobacteriaprofile. Finally, we report that this profile is (1) impacted by gender, (2) inversely correlated with immunosuppressive drugs (calcineurin inhibitors and mammalian target of rapamycin inhibitors), and (3) stable in time. Comparing taxonomic relative abundance and diversity of urinary microbiota between healthy volunteers and tolerant, stable, and minimally immunosuppressed kidney transplanted recipients, this study identifies and associates a specific Proteobacteriaprofile in the urine of kidney transplanted recipients with spontaneous tolerance.

Published
2020
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