1. Perioperative atrial arrhythmias in noncardiothoracic patients: a review of risk factors and treatment strategies in the veteran population
- Author
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Shubhada Sansgiry, Carlos H. Palacio, Faisal G. Bakaeen, Jennifer Marye Burris, Anuradha Subramanian, and Samir S. Awad
- Subjects
medicine.medical_specialty ,Premature atrial contraction ,Hospitals, Veterans ,Population ,Electric Countershock ,Amiodarone ,law.invention ,Coronary artery disease ,law ,Risk Factors ,Internal medicine ,Atrial Fibrillation ,Medicine ,Humans ,Hospital Mortality ,Risk factor ,education ,Perioperative Period ,Aged ,Retrospective Studies ,Veterans ,education.field_of_study ,business.industry ,Incidence ,Retrospective cohort study ,General Medicine ,Perioperative ,biochemical phenomena, metabolism, and nutrition ,Length of Stay ,Middle Aged ,medicine.disease ,Prognosis ,Intensive care unit ,United States ,Surgery ,Intensive Care Units ,Surgical Procedures, Operative ,Practice Guidelines as Topic ,Cardiology ,business ,Anti-Arrhythmia Agents ,medicine.drug ,Follow-Up Studies - Abstract
Background Perioperative atrial arrhythmias (PAAs) in noncardiothoracic patients have poorly defined risk factors and management. Methods The surgical intensive care unit database was queried for patients who developed PAAs from 2008 to 2009. Demographics, comorbidities, preoperative data (electrocardiography, chest x-rays, laboratory results), medications, intraoperative variables, management, and outcomes of atrial arrhythmias were collected. Controls were randomly chosen in a 3:1 ratio. Comparisons were performed using χ2 tests, Student's t tests, or nonparametric comparisons as appropriate. Multivariate logistic regression was performed. Results Five hundred sixty-one patients were admitted to the surgical intensive care unit. Three hundred fifty-four (63%) had noncardiothoracic surgery, and 30 (8.5%) developed PAAs. The mean age of patients with PAAs was 66 ± 7.3 years, compared with 64 ± 11 years for controls (P = NS), with most patients undergoing general (60%) and vascular (33%) surgery. PAA patients were more likely to have coronary artery disease (P = .029), cardiomegaly (P = .011), and premature atrial contractions (P = .016) and to take aspirin (P = .010). On multivariate logistic regression, predictors of atrial arrhythmias were premature atrial contractions, preoperative hypokalemia, intraoperative adverse events, and cardiomegaly. Most PAA patients received amiodarone (63%). Ten percent required electrical cardioversion, and 26% received anticoagulation. PAA patients had significantly longer intensive care unit lengths of stay (P = .032). Conclusion Coronary artery disease, cardiomegaly, hypokalemia, and premature atrial contractions were significantly associated with PAAs in noncardiothoracic patients. Prospective studies are needed to define treatment guidelines.
- Published
- 2010