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Examines the potential for several lipopolysaccharides obtained from Escherichia coli and Pseudomonas aeruginosa to release neutrophil chemotactic activity (NCA) from lung cells. Molecular-sieve column chromatography; Inhibition of the release of NCA by cycloheximide and lipoxygenase inhibitors; Experiments with blocking antibodies.

Investigates whether smoke extract stimulates lung fibroblasts to release neutrophil and monocyte chemotactic activities. Time-related release of neutrophil and monocyte chemotactic activities in response to smoke extract; Partial characterization of released neutrophil and monocyte chemotactic activities; Trypsin sensitivity of the chemotactic activity.

Evaluates the chemotactic responses of human monocytes to monocyte chemoattractant protein-1 (MCP-1) incubated with peroxynitrite or the peroxynitrite generator 3-morpholinosydnonimine (SIN-1) in vitro. Nitration of tyrosine by peroxynitrite; Suggestion that peroxynitrite may play a role in regulation of MCP-1-induced monocyte chemotaxis.

Tests the hypothesis that bleomycin stimulates A549 cells, a type II pneumocyte cell line, to release neutrophil and monocyte chemotactic activities (NCA and MCA). Harvesting of A549 cell supernatant fluids; Partial characterization of the released NCA amd MCA; Performance of checkerboard analysis.

Focuses on the release of the granulocyte colony-stimulating factor (G-CSF) by alveolar type II-like cells, with reference to the neutrophil chemotactic activity. Evaluation of the potential of A549 cells; What the sequestration of peripheral blood neutrophils within the lung is characteristic of; Reference to the significant role the G-CSF plays.

Presents a study which examined the possibility of human lung fibroblasts (HLFs) releasing the mediators which are responsible for monocyte chemokinetic activity (MCA) constitutively. Identification of four peaks of MCA; Inhibition of corresponding molecular-weight peaks separated by molecular-sieve column; Performance of the chemotaxis assay.

Looks at a study which investigated the important role of neurological transmitters which include acetylcholine (ACh), substance P and calcitonin gene-related peptides in the regulation of airway tone. In-depth look at bronchial asthma patients; Impact of anticholinergic drugs on the airways; Methodology used to conduct the study; Results of the study.

Presents information on an experiment where researchers studied the performance of type 11 pneumocyte cells with regards to monocyte chemoattractant activity (MCA). Details on the experiment; Methodology used during the experiment; Names of materials used; Information on the findings which were ascertained; Implications of the findings.

Demonstrates that human lung fibroblasts release chemotactic activity for neutrophils and monocytes in response to cyclophosphamide in a dose- and time-dependent manner. Indication that both neutrophil and monocyte activities were chemotactic; Suggestion that lung fibroblasts may modulate inflammatory cell recruitment into the lung by releasing neutrophil and monocyte in response to cyclophosphamide.