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Focuses on a study on the effects of periodic infusions of melatonin or the melatonin agonist S20098 of variable duration or pattern on the circadian rhythms of rats. Methodology of the study; Results and discussion; Conclusion.

Presents information on a study which investigated the possibility that interstrain differences in the diurinal pattern of wheel running activity rhythms are reflected in the melatonin profiles of rats. Urine collection; Collection of plasma and pineal glands; Discussion of results.