1. Visual function more than 10 years after optic neuritis: experience of the optic neuritis treatment trial
- Author
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Mark J. Kupersmith, William T. Shults, David I. Kaufman, John L. Keltner, Silvia Orengo-Nania, Eric R. Eggenberger, Sarkis M. Nazarian, Peter J. Savino, Roy W. Beck, James J. Corbett, Barrett Katz, Michael C. Brodsky, Jonathan D. Trobe, M. Tariq Bhatti, Pamela S. Moke, Neil R. Miller, James Goodwin, Craig H. Smith, Michael Wall, Dongyuan Xing, Edward G. Buckley, Robin L. Gal, and Georgia A. Chrousos
- Subjects
Adult ,Male ,medicine.medical_specialty ,Visual acuity ,Multiple Sclerosis ,Optic Neuritis ,genetic structures ,Adolescent ,media_common.quotation_subject ,Visual Acuity ,law.invention ,Contrast Sensitivity ,Randomized controlled trial ,law ,Recurrence ,Ophthalmology ,Surveys and Questionnaires ,medicine ,Contrast (vision) ,Health Status Indicators ,Humans ,Optic neuritis ,Vision test ,Glucocorticoids ,media_common ,business.industry ,Multiple sclerosis ,Vision Tests ,Middle Aged ,medicine.disease ,eye diseases ,United States ,Visual field ,Clinical trial ,National Institutes of Health (U.S.) ,Quality of Life ,Female ,sense organs ,medicine.symptom ,Visual Fields ,business ,Follow-Up Studies - Abstract
PURPOSE To assess visual function more than 10 years after an episode of optic neuritis in patients enrolled in the Optic Neuritis Treatment Trial. DESIGN Longitudinal follow-up of a randomized clinical trial. METHODS Vision testing included measures of visual acuity, contrast sensitivity, and visual field. Quality of life was assessed with the National Eye Institute Visual Function Questionnaire. RESULTS Examinations were completed on 319 patients. In most patients, visual function test results in the eyes that experienced optic neuritis at study entry ("affected eyes") were normal or only slightly abnormal after 9.9 to 13.7 years. Visual acuity in the affected eyes was >or=20/20 in 74%, 20/25 to 20/40 in 18%
- Published
- 2004