11 results on '"Whitten P"'
Search Results
2. Risk factors for falls among Iowa farmers: A case-control study nested in the Agricultural Health Study
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Sprince, Nancy L., Zwerling, Craig, Lynch, Charles F., Whitten, Paul S., Thu, Kendall, Gillette, Patricia P., Burmeister, Leon F., and Alavanja, Michael C.R.
- Abstract
Farmers are at increased risk for fall-related injury compared with other occupations. Little is known about risk factors for non-fatal falls on the farm. This case-control study, nested within the Agricultural Health Study, aimed to assess risk factors for work-related falls among Iowa farmers. A screener questionnaire sent to 6,999 farmers in 1998 identified 79 farmers who reported a fall-related farm injury that required medical advice or treatment in the previous year. Multivariable logistic regression analysis was used to assess several possible risk factors for injury among these farmers compared with 473 farmers with no injury in the previous year. There were significant associations between fall-related farm injury and age between 40 and 64 years (OR = 2.21; 95% CI = 1.204.07), doctor-diagnosed arthritis/rheumatism (OR = 2.05; 95% CI = 1.113.79), difficulty hearing normal conversation (even with a hearing aid, in the case of those who used one) (OR = 1.82; 95% CI = 1.073.08), and taking medications regularly (OR = 1.80; 95% CI = 1.023.18). Aging and health impairments, such as arthritis and hearing difficulties, are risk factors for which accommodations and preventive strategies can be devised to prevent fall-related injuries on the farm. Am. J. Ind. Med. 44:265272, 2003. © 2003 Wiley-Liss, Inc.
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- 2003
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3. Risk factors for back pain among male farmers: Analysis of Iowa Farm Family Health and Hazard Surveillance Study
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Park, Hyesook, Sprince, Nancy L., Whitten, Paul S., and Burmeister, Leon F.
- Abstract
Back pain causes considerable morbidity, disability, and economic loss among workers. Farmers handle heavy objects, often in awkward postures. However, the prevalence of back pain among farmers and the risk factors associated with back pain are not well known. In this study, we assess the frequency of risk factors for back pain among 287 Iowa male farmers. From 1992 to 1994, using a mail questionnaire, we collected data on potential risk factors for back pain. Eighteen months later, we surveyed occurrence of back pain as the outcome measure. Thirty-one percent of farmers reported having daily back pain for a week or more during the past 12 months compared to 18.5% in the general working population. Using a multiple logistic regression model, we found two factors associated with back pain: 4559 years of age (OR = 2.13, 95% CI 1.024.43) and having a non-agricultural job as the major occupation (OR = 2.02, 95% CI 0.984.17, P = 0.055). Farmers had a significantly higher prevalence of back pain than the general working population. Middle-aged farmers and those with additional non-agricultural jobs had the highest risk for back pain. Am. J. Ind. Med. 40:646654, 2001. © 2001 Wiley-Liss, Inc
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- 2001
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4. Nested case‐control analysis of high pesticide exposure events from the Agricultural Health Study
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Alavanja, Michael C. R., Sprince, Nancy L., Oliver, Eugene, Whitten, Paul, Lynch, Charles F., Gillette, Patricia P., Logsden‐Sacket, Nyla, and Zwerling, Craig
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- 2001
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5. Respiratory symptoms: Associations with pesticides, silos, and animal confinement in the Iowa Farm Family Health and Hazard Surveillance Project
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Sprince, Nancy L., Lewis, Mary Q., Whitten, Paul S., Reynolds, Stephen J., and Zwerling, Craig
- Abstract
Farmers are at risk for airways diseases resulting from exposures which include organic agents and chemicals on the farm. Few data on airways disease and farm exposures are available from population-based studies. The Iowa Farm Family Health and Hazard Surveillance Project provided the opportunity to assess associations between symptoms of airway disease and several farm exposures, including pesticides, grain dust, animal confinement, and exposures from silos, in a population-based study. A stratified two-stage cluster sample was used to provide a representative farmer sample from the state. Participants provided questionnaire responses concerning demographic, respiratory symptoms, smoking, and exposure information. Associations between farm exposures and airways disease symptoms were assessed in the 385 farmer participants using χ2 analysis and logistic regression analysis adjusting for age and smoking. The most frequently reported respiratory symptoms were flu-like symptoms in connection with dusty work (22%), dyspnea (21%), and phlegm (15%). Current smoking was uncommon (13%). Among farmers, applying pesticides to livestock was associated with significantly increased odds of phlegm (OR = 1.91, 95% CI 1.023.57), chest ever wheezy (OR = 3.92, 95% CI 1.768.72), and flu-like symptoms (OR = 2.93, 95% CI 1.695.12) in models adjusting for age and smoking. Conventional vertical silos were significantly associated with increased odds of chest ever wheezy (OR = 2.75, 95% CI 1.236.12) and flu-like symptoms (OR = 2.40, 95% CI 1.314.37). There were also significant associations between several respiratory symptoms and the presence of animal confinement facilities on the farm. The association between insecticide application to livestock and symptoms of airways disease is a new finding that could lead to further study of specific airway responses and exposures associated with this practice. Results confirming associations between respiratory symptoms and conventional vertical silos may be important in future studies aimed at prevention and control of exposures in those farm buildings. Am. J. Ind. Med. 38:455462, 2000. © 2000 Wiley-Liss, Inc.
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- 2000
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6. Prevalence of elevated blood leads and exposure to lead in construction trades in Iowa and Illinois
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Reynolds, Stephen J., Seem, Rohit, Fourtes, Laurence J., Sprince, Nancy L., Johnson, John, Walkner, Laurie, Clarke, William, and Whitten, Paul
- Abstract
Despite lowering of the permissible exposure level for lead in construction from 200 to 50 μg/m3 in 1993, excessive lead exposure continues to be a problem. Relatively little data are available from the Midwestern U.S. on the environmental lead concentrations generated during various construction activities and the potential for worker exposure. This study characterized the prevalence of blood lead concentrations in high-risk construction trades in Iowa/Illinois, and identified risk factors for occupational exposure to lead in these construction workers. A sample of 459 workers was selected from the total population of all union members from trade groups of painters, plumbers/pipefitters, ironworkers, laborers, and electricians. Participants completed an interviewer-administered questionnaire obtaining information on demographics, symptoms, occupational history, work practices, personal protective equipment, and training. Venous blood samples were collected from each participant and analyzed for blood lead (using atomic absorption spectroscopy) and free erythrocyte protoporphyrin levels. Blood lead levels (BLLs) of construction workers ranged from 0.1 to 50 μg/dL. Geometric mean blood lead concentrations by trade group were: laborers (7.6 μg/dL, n = 80); painters (5.9 μg/dL, n = 83); ironworkers (5.2 μg/dL, n = 87); plumbers (4.4 μg/dL, n = 82); electricians (2.4 μg/dL, n = 91). Blood lead levels for painters and laborers were significantly higher than other trade groups, and levels for electricians were significantly lower (p < 0.01). Participants reported working primarily on commercial and industrial projects including new construction, renovation, and demolition. There were significant differences between the types of projects performed by different trade groups with laborers performing more highway/bridge renovation (p < 0.01), and plumbers reporting more residential remodeling (p = 0.05), repair of water lines containing lead (p = 0.04), or work on lead joints (p < 0.01). In addition to trade, elevated blood lead levels were associated with the type of construction project (especially bridge renovation and residential remodeling) and activities that include welding, cutting, rivet busting. The age of the home in which the worker lived, and hobbies such as casting/smelting lead for bullets or sinkers, were also important risk factors. Compliance with OSHA's Construction Lead Standard, and implementation of good occupational health and safety practices in general, was poor. Blood lead levels of 459 construction workers differed by the type of trade, type of project and specific job activity owing to differences in the inherent exposure potential of each task. Although the numbers of workers performing lead abatement projects were small, the trend for lower BLL in this group provides evidence that training, implementation of engineering controls, and proper use of personal protective equipment such as respirators is effective in controlling lead poisoning. Am. J. Ind. Med. 36:307316, 1999. © 1999 Wiley-Liss, Inc.
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- 1999
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7. Work‐related injuries among Iowa farm operators: An analysis of the Iowa Farm Family Health and Hazard Surveillance Project
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Lewis, Mary Q., Sprince, Nancy L., Burmeister, Leon F., Whitten, Paul S., Torner, James C., and Zwerling, Craig
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In 1994, the Iowa Farm Family Health and Hazard Surveillance Project carried out a two‐stage, stratified, cluster survey of Iowa farms using a mail survey. With data from this representative sample of Iowa farmers, we examined the associations between farm‐work–related injuries and possible risk factors for 390 principal farm operators. Forty (10.3%) of these operators reported being injured while doing farm work. We developed a logistic regression to assess associations between potential risk factors and injury. We found three factors significantly associated with injury: younger age (odds ratio [OR] = 3.1, confidence interval [CI] = 1.1–9.3), having an impairment or health problem that limits work (OR = 2.4, CI = 1.5–3.8), and hand or arm exposure to acids or alkalis (OR = 2.6, CI = 1.1–5.9). In the univariate analysis, safety training did not seem to protect farmers from injuries. Am. J. Ind. Med. 33:510–517, 1998. Published 1998 Wiley‐Liss, Inc.
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- 1998
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8. Lead poisoning among construction workers renovating a previously deleaded bridge
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Reynolds, Stephen J., Fuortes, Laurence J., Garrels, Rick L., Whitten, Paul, and Sprince, Nancy L.
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This study evaluated lead poisoning among construction workers renovating a previously deleaded bridge. Twelve of 44 tested workers had blood leads exceeding 20 μg/dL. One was 50 μg/dL and two exceeded 40 μg/dL. Following medical intervention, blood leads dropped significantly, while ZPPs did not. Renovation released lead that had been inaccessible during deleading. Workers did not use engineering controls or respirators, change clothes, wash hands, or shower. Intervention included a lead-compliance program with provisions for exposure evaluation, training, hygiene, and engineering controls. Construction contractors and workers need to be aware that deleading of bridges and other structures may not remove lead from inaccessible locations. In particular, owners of these structures should specify provisions for anticipating and controlling this hazard in contracts. Am. J. Ind. Med. 31:319323, 1997. © 1997 Wiley-Liss, Inc.
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- 1997
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9. Longitudinal evaluation of dose-response relationships for environmental exposures and pulmonary function in swine production workers.
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Reynolds SJ, Donham KJ, Whitten P, Merchant JA, Burmeister LF, and Popendorf WJ
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- Adult, Animal Husbandry, Animals, Cohort Studies, Dose-Response Relationship, Drug, Dust analysis, Endotoxins analysis, Forced Expiratory Volume physiology, Humans, Longitudinal Studies, Middle Aged, Occupational Exposure analysis, Time Factors, Agriculture, Dust adverse effects, Endotoxins adverse effects, Forced Expiratory Volume drug effects, Occupational Exposure adverse effects, Swine
- Abstract
Studies describing respiratory health hazards for workers in swine production facilities have been published in the United States, Sweden, Canada, the Netherlands, and Denmark. Up to 50% of these workers experience bronchitis, organic dust toxic syndrome, hyper-reactive airways disease, chronic mucous membrane irritation, and other respiratory effects. These studies clearly point to the fact that this occupational environment poses a significant health risk hazard, and that control methods are needed to protect the worker. Before precise control strategies can be developed, implemented, and evaluated, dose-response studies are required to determine acceptable target levels for exposure. A previous manuscript described the development of multiple regression equations characterizing the relationships between environmental exposures and pulmonary response in a cohort of 207 swine producers. Baseline pulmonary function was included as a significant predictor of cross-shift decrements in pulmonary function in addition to personal measurements of dust, endotoxin, and ammonia concentrations. These equations were then used to predict specific exposure levels of dust and ammonia that could be expected to elicit significant decrements in cross-shift pulmonary function. This paper presents the results from analysis of follow-up data obtained on this same cohort 2 years after the initial measurements. At the second measurement period of the study (time-2), swine workers were found to have a mean cross-shift decrease in FEV1 of 2%. Cross-shift change in FEV1 was significantly correlated with personal exposures to total dust, total endotoxin, respirable endotoxin, and ammonia. The magnitude of the decrease in FEV1 was associated with increasing airborne concentrations of these environmental parameters thus confirming the dose-response relationship observed in the initial study (time-1). The correlation of dust with FEV1 changes in workers with more than 6 years of exposure (time-1 data) and more than 10 years of exposure (time-2 data) suggests that dust exposure is an important factor in chronic respiratory disease. Additionally, the correlation of endotoxins with FEV1 changes in the group with less than 6 years exposure (time-2 data) suggests endotoxins may have more significance for subacute respiratory effects. The agreement between observed cross-shift FEV1 changes measured in time-2 with changes predicted using regression equations derived from time-1 data demonstrates a consistent dose-response relationship over time for this cohort of swine production workers. This finding provides further support for conclusions of the previous study that levels of 2.5 mg/m3 (total dust) and 7.5 ppm (ammonia) are reasonable guidelines for occupational exposure limits in this environment.
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- 1996
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10. Effect of recall period on the reporting of occupational injuries among older workers in the Health and Retirement Study.
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Zwerling C, Sprince NL, Wallace RB, Davis CS, Whitten PS, and Heeringa SG
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- Adult, Aged, Cross-Sectional Studies, Female, Humans, Incidence, Linear Models, Male, Middle Aged, Models, Statistical, Reproducibility of Results, Retirement, Risk Factors, Time Factors, United States epidemiology, Accidents, Occupational statistics & numerical data, Bias, Data Collection methods, Mental Recall
- Abstract
Studies of injury morbidity often rely on self-reported survey data. In designing these surveys, researchers must chose between a shorter recall period to minimize recall bias and a longer period to maximize the precision of rate estimates. Using data from the Health and Retirement Study, which employed a recall period of 1 year, we examined the effect of the recall period on rates of occupational injuries among older workers as well as upon rate ratios of these injuries for nine risk factors. We fit a stochastic model to the occupational injury rates as a function of time before the interview and used this model to estimate what the injury rates would have been had we used a 4-week recall period. The adjusted occupational injury rate of 5.9 injuries per 100 workers per year was 36% higher than the rate based on a 1-year recall period. Adjustment for recall period had much less effect on rate ratios, which typically varied by < 10%. Our work suggests that self-reported surveys with longer recall periods may be used to estimate occupational injury rates and also may be useful in studying the associations between occupational injuries and a variety of risk factors.
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- 1995
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11. Respiratory dysfunction in swine production facility workers: dose-response relationships of environmental exposures and pulmonary function.
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Donham KJ, Reynolds SJ, Whitten P, Merchant JA, Burmeister L, and Popendorf WJ
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- Adult, Age Factors, Air Pollutants, Occupational adverse effects, Air Pollutants, Occupational analysis, Ammonia adverse effects, Ammonia analysis, Animals, Dust adverse effects, Dust analysis, Endotoxins adverse effects, Endotoxins analysis, Forced Expiratory Volume physiology, Forecasting, Humans, Iowa, Lung Diseases physiopathology, Male, Maximal Midexpiratory Flow Rate physiology, Occupational Diseases physiopathology, Regression Analysis, Vital Capacity physiology, Animal Husbandry, Lung physiopathology, Lung Diseases etiology, Occupational Diseases etiology, Occupational Exposure, Swine
- Abstract
Human respiratory health hazards for people working in livestock confinement buildings have been recognized since 1974. However, before comprehensive control programs can be implemented, more knowledge is needed of specific hazardous substances present in the air of these buildings, and at what concentrations they are harmful. Therefore, a medical epidemiological and exposure-response study was conducted on 207 swine producers using intensive housing systems (108 farms). Dose-response relationships between pulmonary function and exposures are reported here. Positive correlations were seen between change in pulmonary function over a work period and exposure to total dust, respirable dust, ammonia, respirable endotoxin, and the interactions of age-of-producer and dust exposure and years-of-working-in-the-facility and dust exposure. Relationships between baseline pulmonary function and exposures were not strong and therefore, not pursued in this study. The correlations between exposure and response were stronger after 6 years of exposure. Multiple regression models were used to identify total dust and ammonia as the two primary environmental predictors of pulmonary function decrements over a work period. The regression models were then used to determine exposure concentrations related to pulmonary function decrements suggestive of a health hazard. Total dust concentrations > or = 2.8 mg/m3 were predictive of a work period decrement of > or = 10% in FEV1. Ammonia concentrations of > or = 7.5 ppm were predictive of a > or = 3% work period decrement in FEV1. These predictive concentrations were similar to a previous dose-response study, which suggested 2.5 mg/m3 of total dust and 7 ppm of NH3 were associated with significant work period decrements. Therefore, dust > or = 2.8 mg/m3 and ammonia > or = 7.5 ppm should be considered reasonable evidence for guidelines regarding hazardous exposure concentrations in this work environment.
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- 1995
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