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Start Over Descriptor "Hypochromic" Journal american journal of hematology
2 results on '"Hypochromic"'

1. Parenteral iron therapy and phosphorus homeostasis: A review

Author

Kalantar‐Zadeh, Kamyar, Ganz, Tomas, Trumbo, Henry, Seid, Melvin H, Goodnough, Lawrence T, and Levine, Michael A

Subjects
Kidney Disease, Anemia, Hypochromic, Calcitriol, Ferric Compounds, Fibroblast Growth Factor-23, Fibroblast Growth Factors, Homeostasis, Humans, Hypophosphatemia, Infusions, Parenteral, Iron, Iron Deficiencies, Kidney, Malabsorption Syndromes, Maltose, Osteomalacia, Parathyroid Hormone, Phosphorus, Phosphorus, Dietary, Cardiorespiratory Medicine and Haematology, Immunology
Abstract

Phosphorus has an essential role in cellular and extracellular metabolism; maintenance of normal phosphorus homeostasis is critical. Phosphorus homeostasis can be affected by diet and certain medications; some intravenous iron formulations can induce renal phosphate excretion and hypophosphatemia, likely through increasing serum concentrations of intact fibroblast growth factor 23. Case studies provide insights into two types of hypophosphatemia: acute symptomatic and chronic hypophosphatemia, while considering the role of pre-existing conditions and comorbidities, medications, and intravenous iron. This review examines phosphorus homeostasis and hypophosphatemia, with emphasis on effects of iron deficiency and iron replacement using intravenous iron formulations.

Published
2021

2. Parenteral iron therapy and phosphorus homeostasis: A review

Author

Lawrence T. Goodnough, Melvin H. Seid, Michael A. Levine, Henry Trumbo, Kamyar Kalantar-Zadeh, and Tomas Ganz

Subjects
Fibroblast growth factor 23, medicine.medical_specialty, Hypochromic, Infusions, Anemia, Hypophosphatemia, Iron, Immunology, Dietary, chemistry.chemical_element, Cardiorespiratory Medicine and Haematology, urologic and male genital diseases, Kidney, Ferric Compounds, Phosphorus metabolism, Calcitriol, Malabsorption Syndromes, Parenteral, Internal medicine, medicine, Homeostasis, Humans, Infusions, Parenteral, Maltose, Anemia, Hypochromic, business.industry, Phosphorus, Kidney metabolism, Critical Review, Hematology, Iron deficiency, Iron Deficiencies, medicine.disease, Fibroblast Growth Factors, Fibroblast Growth Factor-23, Endocrinology, chemistry, Parathyroid Hormone, Osteomalacia, Phosphorus, Dietary, Renal phosphate excretion, business
Abstract

Phosphorus has an essential role in cellular and extracellular metabolism; maintenance of normal phosphorus homeostasis is critical. Phosphorus homeostasis can be affected by diet and certain medications; some intravenous iron formulations can induce renal phosphate excretion and hypophosphatemia, likely through increasing serum concentrations of intact fibroblast growth factor 23. Case studies provide insights into two types of hypophosphatemia: acute symptomatic and chronic hypophosphatemia, while considering the role of pre‐existing conditions and comorbidities, medications, and intravenous iron. This review examines phosphorus homeostasis and hypophosphatemia, with emphasis on effects of iron deficiency and iron replacement using intravenous iron formulations.

Published
2021

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