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Your search keyword '"Chen, Julianne"' showing total 7 results
Start Over Author "Chen, Julianne" Journal american journal of hematology
7 results on '"Chen, Julianne"'

1. Results of a phase I trial with Haploidentical mbIL‐21 ex vivo expanded NK cells for patients with multiply relapsed and refractory AML

Author

Ciurea, Stefan O., primary, Kongtim, Piyanuch, additional, Srour, Samer, additional, Chen, Julianne, additional, Soebbing, Doris, additional, Shpall, Elizabeth, additional, Rezvani, Katayoun, additional, Nakkula, Robin, additional, Thakkar, Aarohi, additional, Troy, Ella C., additional, Cash, Alex A., additional, Behbehani, Gregory, additional, Cao, Kai, additional, Schafer, Jolie, additional, Champlin, Richard E., additional, and Lee, Dean A., additional

Published
2024
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2. Relapse risk and survival in patients with FLT3 mutated acute myeloid leukemia undergoing stem cell transplantation.

Author

Gaballa, Sameh, Saliba, Rima, Oran, Betul, Brammer, Jonathan, Chen, Julianne, Rondon, Gabriela, Alousi, Amin, Kebriaei, Partow, Marin, David, Popat, Uday, Andersson, Borje, Shpall, Elizabeth, Jabbour, Elias, Daver, Naval, Andreeff, Michael, Ravandi, Farhad, Cortes, Jorge, Patel, Keyur, Champlin, Richard, and Ciurea, Stefan

Subjects
Adolescent, Adult, Aged, Female, Hematopoietic Stem Cell Transplantation, Humans, Leukemia, Myeloid, Acute, Male, Middle Aged, Mutation, Neoplasm, Residual, Polymerase Chain Reaction, Preoperative Period, Prognosis, Recurrence, Remission Induction, Retrospective Studies, Risk, Survival Analysis, Survival Rate, Young Adult, fms-Like Tyrosine Kinase 3
Abstract

In patients with AML with FMS-like tyrosine kinase 3 (FLT3) mutations, the significance of minimal residual disease (MRD) detected by PCR before allogeneic stem cell transplantation (SCT) on outcomes after transplant remains unclear. We identified 200 patients with FLT3-AML who underwent SCT at our institution. Disease status at transplant was: first or second complete remission (CR1/CR2, n = 119), high-risk CR (third or subsequent CR, marrow hypoplasia, or incomplete count recovery) (CR-HR, n = 31), and morphological evidence of active disease (AD, n = 50). The median follow-up was 27 months, and the 2-year overall and progression-free survival were 43% and 41%, respectively. Relapse was highest in the AD group (85%) and the CR-HR FLT3 MRD positive group (72%), followed by CR-HR FLT3 MRD negative (58%), CR1/CR2 FLT3 MRD positive (39%), and lowest in the CR1/CR2 FLT3 MRD negative group (23%). On multivariate analysis, independent factors influencing the risk of relapse were detectable morphological disease and FLT3 MRD by PCR pre-transplant. Factors that did not influence the relapse risk included: age, graft type, graft source, type of FLT3 mutation, or conditioning intensity. Morphologic and molecular remission status at the time of transplant were key predictors of disease relapse and survival in patients with FLT3-AML.

Published
2017

3. Evolving trends and outcomes in older patients with acute myeloid leukemia including allogeneic stem cell transplantation.

Author

Bazinet, Alexandre, Kantarjian, Hagop, Arani, Naszrin, Popat, Uday, Bataller, Alex, Sasaki, Koji, DiNardo, Courtney D., Daver, Naval, Yilmaz, Musa, Abbas, Hussein A., Short, Nicholas J., Issa, Ghayas, Jabbour, Elias, Pierce, Sherry A., Chen, Julianne, Garcia, Ricky, Konopleva, Marina, Garcia‐Manero, Guillermo, Alousi, Amin, and Shpall, Elizabeth J.

Published
2023
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4. Allogeneic hematopoietic stem cell transplantation versus hypomethylating agents in patients with myelodysplastic syndrome: A retrospective case–control study

Author

Jabbour, Elias, Mathisen, Michael S., Garcia-Manero, Guillermo, Champlin, Richard, Popat, Uday, Khouri, Issa, Giralt, Sergio, Kadia, Tapan, Chen, Julianne, Pierce, Sherry, Koca, Ebru, Daver, Naval, Tanaka, Maria, Rondon, Gabriela, Oran, Betul, Parmar, Simrit, Kantarjian, Hagop, and de Lima, Marcos

Published
2013
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5. Haploidentical transplants for patients with relapse after the first allograft

Author

Srour, Samer A., primary, Kongtim, Piyanuch, additional, Rondon, Gabriela, additional, Chen, Julianne, additional, Petropoulos, Demetrios, additional, Ramdial, Jeremy, additional, Popat, Uday, additional, Kebriaei, Partow, additional, Qazilbash, Muzaffar, additional, Shpall, Elizabeth J., additional, Champlin, Richard E., additional, and Ciurea, Stefan O., additional

Published
2020
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6. Haploidentical transplants for patients with graft failure after the first allograft

Author

Kongtim, Piyanuch, primary, Bittencourt, Maria, additional, Srour, Samer A., additional, Ramdial, Jeremy, additional, Rondon, Gabriela, additional, Chen, Julianne, additional, Khouri, Issa, additional, Betul, Oran, additional, Popat, Uday, additional, Olson, Amanda, additional, Bashir, Qaiser, additional, Shpall, Elizabeth J., additional, Kebriaei, Partow, additional, Champlin, Richard E., additional, and Ciurea, Stefan O., additional

Published
2020
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