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Your search keyword '"Ahnen, Dennis J."' showing total 11 results
Start Over Author "Ahnen, Dennis J." Journal american journal of gastroenterology
11 results on '"Ahnen, Dennis J."'

3. Colonoscopy vs. Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM): Rationale for Study Design

Author

Dominitz, Jason A, primary, Robertson, Douglas J, additional, Ahnen, Dennis J, additional, Allison, James E, additional, Antonelli, Margaret, additional, Boardman, Kathy D, additional, Ciarleglio, Maria, additional, Del Curto, Barbara J, additional, Huang, Grant D, additional, Imperiale, Thomas F, additional, Larson, Meaghan F, additional, Lieberman, David, additional, O'Connor, Theresa, additional, O'Leary, Timothy J, additional, Peduzzi, Peter, additional, Provenzale, Dawn, additional, Shaukat, Aasma, additional, Sultan, Shahnaz, additional, Voorhees, Amy, additional, Wallace, Robert, additional, and Guarino, Peter D, additional

Published
2017
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4. Knowledge and Uptake of Genetic Counseling and Colonoscopic Screening Among Individuals at Increased Risk for Lynch Syndrome and their Endoscopists from the Family Health Promotion Project

Author

Patel, Swati G, primary, Ahnen, Dennis J, additional, Kinney, Anita Y, additional, Horick, Nora, additional, Finkelstein, Dianne M, additional, Hill, Deirdre A, additional, Lindor, Noralane M, additional, MaCrae, Finlay, additional, and Lowery, Jan T, additional

Published
2016
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6. Serrated Lesions of the Colorectum: Review and Recommendations From an Expert Panel

Author

Rex, Douglas K, primary, Ahnen, Dennis J, additional, Baron, John A, additional, Batts, Kenneth P, additional, Burke, Carol A, additional, Burt, Randall W, additional, Goldblum, John R, additional, Guillem, José G, additional, Kahi, Charles J, additional, Kalady, Matthew F, additional, O′Brien, Michael J, additional, Odze, Robert D, additional, Ogino, Shuji, additional, Parry, Susan, additional, Snover, Dale C, additional, Torlakovic, Emina Emilia, additional, Wise, Paul E, additional, Young, Joanne, additional, and Church, James, additional

Published
2012
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10. Serrated polyposis: the last (or only the latest?) frontier of familial polyposis?

Author

Lanspa SJ, Ahnen DJ, and Lynch HT

Subjects
Female, Humans, Male, Colonic Polyps genetics, Neoplasms genetics
Abstract

Serrated polyps are thought to be precursors of ~15% of colorectal cancers and clinical criteria for a serrated polyposis (SP) syndrome have been proposed. In this issue of American Journal of Gastroenterology, Win et al. report that family members of individuals who meet the clinical criteria for SP are at increased risk for colorectal and possibly pancreatic cancer. The important data presented by Win et al. strongly support the concept that familial SP exists and help define the patterns of risk in this syndrome. The paper also illustrates the difficulties of trying to define a genetic syndrome on the basis of largely retrospective clinical data and highlights the importance of efforts to define the genetic basis of familial SP and to study these families in a systematic, prospective manner.

Published
2012
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11. Editorial: Colorectal cancer and statins: reflections from the end of the road.

Author

Ahnen DJ and Byers T

Subjects
Aged, Cohort Studies, Colorectal Neoplasms epidemiology, Dose-Response Relationship, Drug, Female, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors administration & dosage, Incidence, Male, Manitoba epidemiology, Middle Aged, Registries, Research Design, Social Class, Colorectal Neoplasms prevention & control, Hydroxymethylglutaryl-CoA Reductase Inhibitors therapeutic use
Abstract

Statins are among the most widely prescribed drugs in the United States. In addition to their established lipid-lowering and cardiovascular protective effect, some case-control studies have suggested that statins could have chemopreventive effects for colorectal cancer (CRC). In this issue of the Journal, Singh et al. examined this question using a potentially powerful population-based "electronic cohort" design, which essentially eliminates many of the biases inherent in case-control and traditional cohort studies. They found no evidence of a chemoprotective effect of statin use, a finding that is consistent with previous cohort and interventional studies that have addressed this issue. We conclude that the best-designed studies of the issue indicate that statin use is neither a major risk factor nor a protective factor for CRC and that we have come very near to the end of the road for the hypothesis relating statins to CRC risk.

Published
2009
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