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Method: This study examined the association between marijuana-related problems and social norms, impulsivity, and perceived use utility among 292 college students. Zero-inflated negative binomial regression was used to simultaneously predict expected nonusers as well as predict counts of reported marijuana-related problems among expected users. Gender, social norms, impulsivity, and perceived use utility were used to predict expected nonusers as well as number of marijuana-related problems among expected users.Results: Only social norms were associated with the prediction of zero-values. In contrast, only perceived use utility was associated with the prediction of number of marijuana-related problems.Conclusions: Results generally are consistent with theories of the differential association of social-environmental and biopsychological variables with use and problems, respectively. Zero-inflated regression models are a useful strategy to examine risk behaviors with low base rates. [ABSTRACT FROM AUTHOR]