1. Mammary Paget disease in Darier disease: beware the wolf in sheep's clothing.
- Author
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Spizuoco A, Jain RD, Stockton T, Kessler SE, and Hamacher KL
- Subjects
- Aged, Biomarkers, Tumor analysis, Biopsy, Breast Neoplasms chemistry, Breast Neoplasms complications, Breast Neoplasms therapy, Darier Disease complications, Darier Disease therapy, Female, Humans, Immunohistochemistry, Keratin-7 analysis, Nipples pathology, Paget's Disease, Mammary chemistry, Paget's Disease, Mammary complications, Paget's Disease, Mammary therapy, Predictive Value of Tests, Skin pathology, Breast Neoplasms diagnosis, Darier Disease diagnosis, Paget's Disease, Mammary diagnosis
- Abstract
This case describes new onset mammary Paget disease arising in the background of Darier disease. Clinically and histologically, lesions of Darier disease can mask the lesions of mammary Paget disease. A high index of suspicion is necessary to diagnose Paget disease in a patient with Darier disease, for a potentially fatal disease could easily be missed.
- Published
- 2012
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