Search

Your search keyword '"Keating, Michael J."' showing total 9 results
Start Over Author "Keating, Michael J." Journal american journal of clinical pathology
9 results on '"Keating, Michael J."'

2. High Serum Thymidine Kinase 1 Level Predicts Poorer Survival in Patients With Chronic Lymphocytic Leukemia

Author

Konoplev, Sergej N., primary, Fritsche, Herbert A., additional, O’Brien, Susan, additional, Wierda, William G., additional, Keating, Michael J., additional, Gornet, Terrie G., additional, St Romain, Susan, additional, Wang, Xuemei, additional, Inamdar, Kedar, additional, Johnson, Malisha R., additional, Medeiros, L. Jeffrey, additional, and Bueso-Ramos, Carlos E., additional

Published
2010
Full Text
View/download PDF

3. Chronic Lymphocytic Leukemia With t(2;14)(p16;q32) Involves the BCL11A and IgH Genes and Is Associated With Atypical Morphologic Features and Unmutated IgVH Genes

Author

Yin, C. Cameron, primary, Lin, Katherine I-Chun, additional, Ketterling, Rhett P., additional, Knudson, Ryan A., additional, Medeiros, L. Jeffrey, additional, Barron, Lynn L., additional, Huh, Yang O., additional, Luthra, Rajyalakshmi, additional, Keating, Michael J., additional, and Abruzzo, Lynne V., additional

Published
2009
Full Text
View/download PDF

9. Fine-needle aspiration biopsy findings in patients with small lymphocytic lymphoma transformed to hodgkin lymphoma.

Author

Catrina Reading F, Schlette EJ, Stewart JM, Keating MJ, Katz RL, and Caraway NP

Subjects
Aged, Biopsy, Fine-Needle, Epstein-Barr Virus Infections diagnosis, Epstein-Barr Virus Infections virology, Female, Flow Cytometry, Herpesvirus 4, Human genetics, Herpesvirus 4, Human isolation & purification, Hodgkin Disease virology, Humans, Leukemia, Lymphocytic, Chronic, B-Cell virology, Lymph Nodes pathology, Male, Middle Aged, RNA, Viral analysis, Cell Transformation, Neoplastic pathology, Hodgkin Disease pathology, Leukemia, Lymphocytic, Chronic, B-Cell pathology
Abstract

Although small lymphocytic lymphoma (SLL) is an indolent lymphoma, approximately 5% of cases can transform to a higher-grade lymphoma, rarely Hodgkin lymphoma (HL). We report the fine-needle aspiration (FNA) results of 6 cases of SLL/chronic lymphocytic leukemia (CLL) that transformed to HL. FNA findings were correlated with the histologic features and clinical follow-up. The patients included 5 men and 1 woman, ranging in age from 49 to 72 years at the time of SLL/CLL diagnosis with time for development of HL ranging from 0 to 95 months (mean, 49.3 months). The FNA diagnoses were SLL with HL transformation (2 cases), SLL with large atypical cells (1 case), and atypical lymphoid proliferation with large atypical cells (3 cases). Flow cytometry performed in 5 cases (2 FNA specimens) demonstrated a monoclonal B-cell population with CD19/CD5 coexpression. The presence of large atypical mononucleated and binucleated cells in lymph node FNA specimens from patients with SLL/CLL with progressive adenopathy should raise the possibility of transformation to HL. In these cases, histologic confirmation is always recommended, not only to differentiate HL transformation from other entities but also for subclassification of HL.

Published
2007
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results