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Your search keyword '"Thomas Ryan"' showing total 3 results
Start Over Author "Thomas Ryan" Journal american journal of clinical dermatology
3 results on '"Thomas Ryan"'

1. Efficacy and Safety of Dupilumab Maintained in Adults ≥ 60 Years of Age with Moderate-to-Severe Atopic Dermatitis: Analysis of Pooled Data from Four Randomized Clinical Trials

Author

Silverberg, Jonathan I, Lynde, Charles W, Abuabara, Katrina, Patruno, Cataldo, de Benedetto, Anna, Zhang, Haixin, Thomas, Ryan B, Bégo-Le-Bagousse, Gaëlle, Khokhar, Faisal A, Vakil, Jignesh, Marco, Ainara Rodríguez, and Levit, Noah A

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Trials and Supportive Activities, Clinical Research, Aging, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Skin, Humans, Adult, Middle Aged, Aged, Dermatitis, Atopic, Quality of Life, Injections, Subcutaneous, Double-Blind Method, Severity of Illness Index, Randomized Controlled Trials as Topic, Treatment Outcome, Dermatology & Venereal Diseases, Clinical sciences
Abstract

BackgroundAdults aged ≥ 60 years are often underrepresented in atopic dermatitis (AD) clinical trials; age-related comorbidities may impact treatment efficacy and safety.ObjectiveThe aim was to report dupilumab efficacy and safety in patients aged ≥ 60 years with moderate-to-severe AD.MethodsData were pooled from four randomized, placebo-controlled dupilumab trials of patients with moderate-to-severe AD (LIBERTY AD SOLO 1 and 2, LIBERTY AD CAFÉ, and LIBERTY AD CHRONOS) and stratified by age (

Published
2023

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