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Your search keyword '"Wilton, Stephen B."' showing total 5 results
Start Over Author "Wilton, Stephen B." Journal american heart journal
5 results on '"Wilton, Stephen B."'

1. A genotype-directed comparative effectiveness trial of Bucindolol and metoprolol succinate for prevention of symptomatic atrial fibrillation/atrial flutter in patients with heart failure: Rationale and design of the GENETIC-AF trial

Author

Piccini, Jonathan P., Connolly, Stuart J., Abraham, William T., Healey, Jeff S., Steinberg, Benjamin A., Al-Khalidi, Hussein R., Dignacco, Patricia, van Veldhuisen, Dirk J., Sauer, William H., White, Michel, Wilton, Stephen B., Anand, Inder S., Dufton, Christopher, Marshall, Debra A., Aleong, Ryan G., Davis, Gordon W., Clark, Richard L., Emery, Laura L., and Bristow, Michael R.

Published
2018
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3. Average daily ischemic versus bleeding risk in patients with ACS undergoing PCI: Insights from the BleeMACS and RENAMI registries

Author

D’Ascenzo, Fabrizio, primary, Biolè, Carloalberto, additional, Raposeiras-Roubin, Sergio, additional, Gaido, Federico, additional, Abu-Assi, Emad, additional, Kinnaird, Tim, additional, Ariza-Solé, Albert, additional, Liebetrau, Christoph, additional, Manzano-Fernández, Sergio, additional, Boccuzzi, Giacomo, additional, Henriques, Jose Paulo Simao, additional, Templin, Christian, additional, Wilton, Stephen B., additional, Omedè, Pierluigi, additional, Velicki, Lazar, additional, Xanthopoulou, Ioanna, additional, Correia, Luis, additional, Cerrato, Enrico, additional, Rognoni, Andrea, additional, Fabrizio, Ugo, additional, Nuñez-Gil, Iván, additional, Montabone, Andrea, additional, Taha, Salma, additional, Fujii, Toshiharu, additional, Durante, Alessandro, additional, Song, Xiantao, additional, Gili, Sebastiano, additional, Magnani, Giulia, additional, Autelli, Michele, additional, Bongiovanni, Federica, additional, Grosso, Alberto, additional, Kawaji, Tetsuma, additional, Blanco, Pedro Flores, additional, Garay, Alberto, additional, Quadri, Giorgio, additional, Alexopoulos, Dimitrios, additional, Queija, Berenice Caneiro, additional, Huczek, Zenon, additional, Paz, Rafael Cobas, additional, González-Juanatey, José Ramón, additional, Fernández, María Cespón, additional, Nie, Shao-Ping, additional, Pousa, Isabel Muñoz, additional, Kawashiri, Masa-aki, additional, Rettegno, Sara, additional, Gallo, Diego, additional, Morbiducci, Umberto, additional, Conrotto, Federico, additional, Dominguez-Rodriguez, Alberto, additional, Valdés, Mariano, additional, Cequier, Angel, additional, Iñiguez-Romo, Andrés, additional, Biondi-Zoccai, Giuseppe, additional, Stone, Gregg W., additional, and De Ferrari, Gaetano Maria, additional

Published
2020
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4. Average daily ischemic versus bleeding risk in patients with ACS undergoing PCI: Insights from the BleeMACS and RENAMI registries.

Author

D'Ascenzo, Fabrizio, Biolè, Carloalberto, Raposeiras-Roubin, Sergio, Gaido, Federico, Abu-Assi, Emad, Kinnaird, Tim, Ariza-Solé, Albert, Liebetrau, Christoph, Manzano-Fernández, Sergio, Boccuzzi, Giacomo, Henriques, Jose Paulo Simao, Templin, Christian, Wilton, Stephen B., Omedè, Pierluigi, Velicki, Lazar, Xanthopoulou, Ioanna, Correia, Luis, Cerrato, Enrico, Rognoni, Andrea, and Fabrizio, Ugo

Abstract

Background: The risk of recurrent ischemia and bleeding after percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) may vary during the first year of follow-up according to clinical presentation, and medical and interventional strategies.Methods: BleeMACS and RENAMI are 2 multicenter registries enrolling patients with ACS treated with PCI and clopidogrel, prasugrel, or ticagrelor. The average daily ischemic and bleeding risks (ADIR and ADBR) in the first year after PCI were the primary end points. The difference between ADBR and ADIR was calculated to estimate the potential excess of bleeding/ischemic events in a given period or specific subgroup.Results: A total of 19,826 patients were included. Overall, in the first year after PCI, the ADBR was 0.008085%, whereas ADIR was 0.008017% (P = .886). In the first 2 weeks ADIR was higher than ADBR (P = .013), especially in patients with ST-segment elevation myocardial infarction or incomplete revascularization. ADIR continued to be, albeit non-significantly, greater than ADBR up to the third month, whereas ADBR became higher, although not significantly, afterward. Patients with incomplete revascularization had an excess in ischemic risk (P = .003), whereas non-ST-segment elevation ACS patients and those on ticagrelor had an excess of bleeding (P = .012 and P = .022, respectively).Conclusions: In unselected ACS patients, ADIR and ADBR occurred at similar rates within 1 year after PCI. ADIR was greater than ADBR in the first 2 weeks, especially in ST-segment elevation myocardial infarction patients and those with incomplete revascularization. In the first year, ADIR was higher than ADBR in patients with incomplete revascularization, whereas ADBR was higher in non-ST-segment elevation ACS patients and in those discharged on ticagrelor. [ABSTRACT FROM AUTHOR]

Published
2020
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