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Your search keyword '"O'Rourke, Robert A."' showing total 36 results
Start Over Author "O'Rourke, Robert A." Journal american heart journal
36 results on '"O'Rourke, Robert A."'

1. Optimal medical therapy with or without percutaneous coronary intervention in women with stable coronary disease: A pre-specified subset analysis of the Clinical Outcomes Utilizing Revascularization and Aggressive druG Evaluation (COURAGE) trial

Author

Acharjee, Subroto, Teo, Koon K., Jacobs, Alice K., Hartigan, Pamela M., Barn, Kulpreet, Gosselin, Gilbert, Tanguay, Jean-Francois, Maron, David J., Kostuk, William J., Chaitman, Bernard R., Mancini, John G.B., Spertus, John A., Dada, Marcin R., Bates, Eric R., Booth, David C., Weintraub, William S., O’Rourke, Robert A., and Boden, William E.

Published
2016
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3. Economics methods in the Clinical Outcomes Utilizing percutaneous coronary Revascularization and Aggressive Guideline-driven drug Evaluation (COURAGE) trial

Author

Weintraub, William S., Barnett, Paul, Chen, Shuo, Hartigan, Pamela, Casperson, Paul, O'Rourke, Robert, Boden, William E., Lewis, Cheryl, Veledar, Emir, Becker, Edmund, Culler, Steven, Kolm, Paul, Mahoney, Elizabeth M., Dunbar, Sandra B., Deaton, Christi, O'Brien, Bernard, Goeree, Ron, Blackhouse, Gordon, Nease, Robert, Spertus, John, Kaufman, Stan, and Teo, Koon

Subjects
Coronary heart disease -- Care and treatment, Coronary heart disease -- Economic aspects, Coronary heart disease -- Research, Transluminal angioplasty -- Patient outcomes, Cost benefit analysis -- Research, Outcome and process assessment (Health Care) -- Economic aspects, Outcome and process assessment (Health Care) -- Research, Cost benefit analysis, Health
Published
2006

4. Design and rationale of the Clinical Outcomes Utilizing Revascularization and Aggressive druG Evaluation (COURAGE) trial: Veterans Affairs Cooperative Studies Program no. 424

Author

Boden, William E., O'Rourke, Robert A., Teo, Koon K., Hartigan, Pamela M., Maron, David J., Kostuk, William, Knudtson, Merril, Dada, Marcin, Casperson, Paul, Harris, Crystal L., Spertus, John A., Shaw, Leslee, Chaitman, Bernard R., Mancini, G.B. John, Berman, Daniel S., and Weintraub, William S.

Subjects
Drug therapy -- Research, Drug therapy -- Patient outcomes, Transluminal angioplasty -- Research, Transluminal angioplasty -- Patient outcomes, Coronary heart disease -- Care and treatment, Health
Published
2006

8. And the beat goes on

Author

O'Rourke, Robert A.

Subjects
Atherosclerosis -- Diagnosis, Heart -- Calcification, Electron beams, Health
Published
2001

9. Acute hemodynamic changes during intravenous dipyridamole thallium imaging early after infarction

Author

Miller, D. Douglas, Scott, Ronald A., Riesmeyer, Jeffrey S., Chaudhuri, Tuhin K., Blumhardt, Ralph, Boucher, Charles A., and O'Rourke, Robert A.

Subjects
Heart attack -- Physiological aspects, Thallium -- Isotopes, Dipyridamole, Health
Abstract

The injection of radioactive thallium-201 can be used to observe the flow of blood through the coronary arteries. The injection of dipyridamole is often used in conjunction with this technique to detect impaired blood flow to the heart muscle past areas of stenosis, or narrowing of the coronary arteries (most often due to atherosclerosis). Narrow segments, which may perform acceptably during normal conditions, may prove inadequate when blood flow increases during stress, and this can be observed using dipyridamole. Although promising, the technique currently remains a subject of investigation, and is not yet routinely used in the evaluation of patients with heart disease. To further evaluate the safety and efficacy of the method, 10 patients recovering from uncomplicated myocardial infarctions (heart attacks) were examined. Three patients developed ischemia (reduced blood supply) and associated angina pectoris (chest pain) during the technique, but the events were not serious. Aminophylline was found to promptly reverse the effects of dipyridamole and return the patient's hemodynamic measurements to baseline. The results confirm that the dipyridamole-thallium imaging technique is effective and safe for patients with myocardial infarction when used in a controlled setting along with aminophylline reversal of the drug effects. However, clinicians should be reminded that there are no data to suggest that the technique is safe for patients with complicated myocardial infarction. In the presence of heart failure, angina, low blood pressure, or ventricular arrhythmias, the technique should be used only with extensive precautions and great care. (Consumer Summary produced by Reliance Medical Information, Inc.)

Published
1989

11. Baseline stress myocardial perfusion imaging results and outcomes in patients with stable ischemic heart disease randomized to optimal medical therapy with or without percutaneous coronary intervention

Author

Shaw, Leslee J., primary, Weintraub, William S., additional, Maron, David J., additional, Hartigan, Pamela M., additional, Hachamovitch, Rory, additional, Min, James K., additional, Dada, Marcin, additional, Mancini, G.B. John, additional, Hayes, Sean W., additional, O'Rourke, Robert A., additional, Spertus, John A., additional, Kostuk, William, additional, Gosselin, Gilbert, additional, Chaitman, Bernard R., additional, Knudtson, Merill, additional, Friedman, John, additional, Slomka, Piotr, additional, Germano, Guido, additional, Bates, Eric R., additional, Teo, Koon K., additional, Boden, William E., additional, and Berman, Daniel S., additional

Published
2012
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12. Design and rationale of the Clinical Outcomes Utilizing Revascularization and Aggressive Dru G Evaluation (COURAGE) trial : Veterans Affairs Cooperative Studies Program no. 424

Author

Boden, William E., O'Rourke, Robert A., Teo, Koon K., Hartigan, Pamela M., Maron, David J., Kostuk, William, Knudtson, Merril, Dada, Marcin, Casperson, Paul, Harris, Crystal L., Spertus, John A., Shaw, Leslee, Chaitman, Bernard R., Mancini, G.B. John, Berman, Daniel S., and Weintraub, William S.

Published
2006
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36. beta-Blocker use following myocardial infarction: low prevalence of evidence-based dosing.

Author

Goldberger JJ, Bonow RO, Cuffe M, Dyer A, Rosenberg Y, O'Rourke R, Shah PK, Smith SC Jr, PACE-MI Investigators, Goldberger, Jeffrey J, Bonow, Robert O, Cuffe, Michael, Dyer, Alan, Rosenberg, Yves, O'Rourke, Robert, Shah, Prediman K, and Smith, Sidney C Jr

Abstract

Background: Quality improvement programs have shown increased use of beta-blockers post-myocardial infarction (MI), but there are no data on whether appropriate doses are administered.Methods: In a prospective registry that enrolled consecutive patients with MI, we evaluated beta-blocker dosing at discharge after MI and 3 weeks later and assessed clinical predictors for treatment with very low doses. We studied 1,971 patients (70.8% male) with a mean age of 63.9 +/- 13.7 years, of whom 48.2% had an ST-elevation MI.Results: beta-Blocker utilization rates following MI were 93.2% at discharge: 20.1% received <25% of target dose, 36.5% received 25% of target dose, 26.4% received 26% to 50% of target dose, and 17.0% received >50% of target dose. Between discharge and 3 weeks, 76.4% had no change in beta-blocker dose, with 11.9% and 11.6% having their dose reduced and increased, respectively. Absence of hypertension, acute percutaneous coronary intervention, older age, and no angiotensin-converting enzyme inhibitor therapy were consistent predictors of treatment with very low beta-blocker doses.Conclusions: Underdosing of beta-blockers is highly prevalent among patients post-MI. This represents an important opportunity in quality improvement for the care of patients who have suffered an MI. [ABSTRACT FROM AUTHOR]

Published
2010
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