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1. Association of AD risk factors with plasma GFAP levels in a memory clinic population

Author

Marizzoni, Moira, primary, Chevalier, Claire, additional, Paquis, Arthur, additional, Zetterberg, Henrik, additional, Blennow, Kaj, additional, Lathuiliere, Aurelien, additional, Ribaldi, Federica, additional, Wyss‐Dominguez, Carine, additional, Blouin, Jean‐Louis, additional, Abramowicz, Marc, additional, Pievani, Michela, additional, Garibotto, Valentina, additional, and Frisoni, Giovanni B, additional

Published
2023
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2. Altered patterns of brain activity during a fMRI memory task in cognitively normal adults carrying the APOE ε4 allele

Author

Corbo, Daniele, primary, Quattrini, Giulia, additional, Saglia, Silvia, additional, Agnelli, Giancarlo, additional, Mega, Anna, additional, Marizzoni, Moira, additional, D'Aprile, Ilari, additional, Cattaneo, Annamaria, additional, Bortoletto, Marta, additional, Gasparotti, Roberto, additional, and Pievani, Michela, additional

Published
2023
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4. A clinical trial of cognitive and biological effects of citrus phytochemicals in subjective cognitive decline: baseline sociodemographic, clinical, and cognitive characteristics

Author

Gatti, Elena, primary, Sgrò, Giovanni, additional, Fiorito, Serena, additional, Genovese, Salvatore, additional, Marchetti, Lorenzo, additional, Palumbo, Lucia, additional, Frisoni, Giovanni, additional, Pievani, Michela, additional, Epifano, Francesco, additional, and Galluzzi, Samantha, additional

Published
2023
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5. Technology in the service of caregiver well‐being: an online psycho‐educational intervention combined with virtual reality

Author

Festari, Cristina, primary, Bonomini, Cristina, additional, Rosini, Sandra, additional, Gattuso, Maria, additional, Solorzano, Claudio Singh, additional, Zanetti, Orazio, additional, Corbo, Daniele, additional, Agnelli, Giancarlo, additional, Ferrari, Clarissa, additional, Gasparotti, Roberto, additional, Morganti, Francesca, additional, and Pievani, Michela, additional

Published
2023
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7. Atrophy of hypothalamic subunits in Alzheimer’s disease

Author

Quattrini, Giulia, primary, Saglia, Silvia, additional, Agosta, Federica, additional, Bagattini, Chiara, additional, Bulgari, Martina, additional, Canu, Elisa, additional, Delai, Mara, additional, Ferrari, Elisabetta, additional, Filippi, Massimo, additional, Fracassi, Claudia, additional, Pievani, Michela, additional, Bortoletto, Marta, additional, and Marizzoni, Moira, additional

Published
2023
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11. Towards fingerprinting and identifiability within the Alzheimer’s continuum using resting‐state functional connectivity

Author

Sara Stampacchia, Saina Asadi, Federica Ribaldi, Szymon Tomczyk, Daniele Altomare, Michela Pievani, Giovanni Frisoni, Enrico Amico, and Valentina Garibotto

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2021
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15. Amygdalar nuclei and hippocampal subfields on MRI: Test‐retest reliability of automated segmentation in old and young healthy volunteers

Author

Agnese Picco, Núria Bargalló, Antonios Drevelegas, Mira Didic, Régis Bordet, Moira Marizzoni, Bernhard W. Müller, Piero Floridi, Björn H. Schott, Michela Pievani, Giovanni B. Frisoni, Jill C. Richardson, Alberto Beltramello, Tilman Hensch, Marco Salvatore, Flavio Nobili, Pierre Payoux, Roberto Tarducci, Jorge Jovicich, Magda Tsolaki, Karl-Titus Hoffmann, Jens Wiltfang, Camillo Marra, Renaud Lopes, Jean-Philippe Ranjeva, Pieter Jelle Visser, Giulia Quattrini, Lucilla Parnetti, Manos Constantinides, Frederik Barkhof, David Bartrés-Faz, Francesca B. Pizzini, Julien Sein, Antonio Ferretti, Olivier Blin, Ute Fiedler, Luca Roccatagliata, Massimo Caulo, Andrea Soricelli, Paolo Maria Rossini, Joost P.A. Kuijer, Helene Gros-Dagnac, Marco Aiello, and Peter Schönknecht

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Automated segmentation, Hippocampal formation, Audiology, Test (assessment), Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Neuroimaging, Healthy volunteers, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Brain aging, Reliability (statistics)
Published
2020
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16. In‐vivo imaging of locus coeruleus integrity at ultra‐high field: A feasibility study

Author

Olivier Reynaud, Paulina Andryszak, Ileana O. Jelescu, Valentina Garibotto, Michela Pievani, Giovanni B. Frisoni, João Jorge, and Jorge Jovicich

Subjects
0303 health sciences, Epidemiology, business.industry, Health Policy, 03 medical and health sciences, Psychiatry and Mental health, Cellular and Molecular Neuroscience, 0302 clinical medicine, Developmental Neuroscience, Neuroimaging, Ultra high field, Locus coeruleus, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Neuroscience, 030217 neurology & neurosurgery, Preclinical imaging, 030304 developmental biology
Published
2020
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19. Amygdalar nuclei and hippocampal subfields on MRI: Test‐retest reliability of automated segmentation in old and young healthy volunteers

Author

Quattrini, Giulia, primary, Pievani, Michela, additional, Jovicich, Jorge, additional, Aiello, Marco, additional, Bargalló, Nuria, additional, Barkhof, Frederik, additional, Bartrés‐Faz, David, additional, Beltramello, Alberto, additional, Pizzini, Francesca B, additional, Blin, Olivier, additional, Bordet, Régis, additional, Caulo, Massimo, additional, Constantinides, Manos, additional, Didic, Mira, additional, Drevelegas, Antonios, additional, Ferretti, Antonio, additional, Fiedler, Ute, additional, Floridi, Piero, additional, Gros‐Dagnac, Helene, additional, Hensch, Tilman, additional, Hoffmann, Karl‐Titus, additional, Kuijer, Joost, additional, Lopes, Renaud, additional, Marra, Camillo, additional, Müller, Bernhard W., additional, Nobili, Flavio, additional, Parnetti, Lucilla, additional, Payoux, Pierre, additional, Picco, Agnese, additional, Ranjeva, Jean‐Philippe, additional, Roccatagliata, Luca, additional, Rossini, Paolo Maria, additional, Salvatore, Marco, additional, Schonknecht, Peter, additional, Schott, Björn H, additional, Sein, Julien, additional, Soricelli, Andrea, additional, Tarducci, Roberto, additional, Tsolaki, Magda, additional, Visser, Pieter Jelle, additional, Wiltfang, Jens, additional, Richardson, Jill, additional, Frisoni, Giovanni B, additional, Marizzoni, Moira, additional, and Consortium, PharmaCog, additional

Published
2020
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20. IC‐P‐040: FUNCTIONAL NETWORK CONNECTIVITY CHANGES IN EARLY AND LATE ONSET ALZHEIMER'S DISEASE

Author

Milena Cobelli, Stefania Orini, Samantha Galluzzi, Silvana Archetti, Michela Pievani, Lorenzo Pini, Giovanni B. Frisoni, Orazio Zanetti, Roberta Baruzzi, Monica Bertocchi, Cristina Geroldi, Maria Cotelli, and Eugenia Chitò

Subjects
Epidemiology, business.industry, Health Policy, Late onset, Disease, Functional networks, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Neuroscience
Published
2018
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21. P2‐370: AMYLOID‐PET FOR MYELIN IMAGING IN ALZHEIMER'S DISEASE

Author

Giulia Merlin, Paulina Andryszak, Valentina Garibotto, Ugo Paolo Guerra, Frédéric Assal, Giordano Savelli, Anna Tarallo, Moira Marizzoni, Michela Pievani, Giovanni B. Frisoni, Aline Mendes, and Federica Ribaldi

Subjects
Pathology, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Amyloid pet, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Myelin, medicine.anatomical_structure, Developmental Neuroscience, Medicine, Neurology (clinical), Geriatrics and Gerontology, business
Published
2018
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22. P2-017: BRAIN NETWORK MODULATION IN ALZHEIMER'S DISEASE AND BEHAVIORAL VARIANT FRONTOTEMPORAL DEMENTIA WITH ELECTRICAL STIMULATION: A PILOT DOUBLE-BLIND RANDOMIZED TRIAL

Author

Michela Pievani, Lorenzo Pini, Clarissa Ferrari, Ilaria Boscolo Galazzo, Chiara Cobelli, Maria Cotelli, Giovanni B. Frisoni, Rosa Manenti, and Francesca B. Pizzini

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2019
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23. IC-P-158: BRAIN NETWORK MODULATION IN ALZHEIMER'S DISEASE AND BEHAVIORAL VARIANT FRONTOTEMPORAL DEMENTIA WITH ELECTRICAL STIMULATION: A PILOT DOUBLE-BLIND RANDOMIZED TRIAL

Author

Rosa Manenti, Michela Pievani, Giovanni B. Frisoni, Maria Cotelli, Ilaria Boscolo Galazzo, Francesca B. Pizzini, Clarissa Ferrari, Lorenzo Pini, and Chiara Cobelli

Subjects
Brain network, Epidemiology, business.industry, Health Policy, Stimulation, Disease, medicine.disease, law.invention, Double blind, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Randomized controlled trial, law, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Neuroscience, Frontotemporal dementia
Published
2019
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24. P2-017: BRAIN NETWORK MODULATION IN ALZHEIMER'S DISEASE AND BEHAVIORAL VARIANT FRONTOTEMPORAL DEMENTIA WITH ELECTRICAL STIMULATION: A PILOT DOUBLE-BLIND RANDOMIZED TRIAL

Author

Pievani, Michela, primary, Pini, Lorenzo, additional, Ferrari, Clarissa, additional, Galazzo, Ilaria Boscolo, additional, Cobelli, Chiara, additional, Cotelli, Maria, additional, Frisoni, Giovanni B., additional, Manenti, Rosa, additional, and Pizzini, Francesca B., additional

Published
2019
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25. IC-P-158: BRAIN NETWORK MODULATION IN ALZHEIMER'S DISEASE AND BEHAVIORAL VARIANT FRONTOTEMPORAL DEMENTIA WITH ELECTRICAL STIMULATION: A PILOT DOUBLE-BLIND RANDOMIZED TRIAL

Author

Pievani, Michela, primary, Pini, Lorenzo, additional, Ferrari, Clarissa, additional, Galazzo, Ilaria Boscolo, additional, Cobelli, Chiara, additional, Cotelli, Maria, additional, Frisoni, Giovanni B., additional, Manenti, Rosa, additional, and Pizzini, Francesca B., additional

Published
2019
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27. [IC‐P‐174]: NETWORK‐BASED MODULATION OF CEREBRAL PERFUSION AND FUNCTIONAL CONNECTIVITY IN ALZHEIMER's DISEASE

Author

Ilaria Boscolo Galazzo, Rosa Manenti, Michela Pievani, Giovanni B. Frisoni, Chiara Cobelli, Lorenzo Pini, Gloria Menegaz, Clarissa Ferrari, Elisa M. Ciceri, Francesca B. Pizzini, and Maria Cotelli

Subjects
Epidemiology, business.industry, Health Policy, Functional connectivity, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Modulation, Medicine, Neurology (clinical), Geriatrics and Gerontology, Cerebral perfusion pressure, business, Neuroscience
Published
2017
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28. [P2–334]: NETWORK‐BASED MODULATION OF CEREBRAL PERFUSION AND FUNCTIONAL CONNECTIVITY IN ALZHEIMER's DISEASE

Author

Ilaria Boscolo Galazzo, Francesca B. Pizzini, Lorenzo Pini, Clarissa Ferrari, Chiara Cobelli, Gloria Menegaz, Elisa M. Ciceri, Maria Cotelli, Rosa Manenti, Giovanni B. Frisoni, and Michela Pievani

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2017
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29. [P3–199]: ABNORMALITIES OF CORTICAL NEURAL SYNCHRONIZATION MECHANISMS IN SUBJECTS WITH MILD COGNITIVE IMPAIRMENT DUE TO ALZHEIMER's AND PARKINSON's DISEASES: AN EEG STUDY

Author

Dag Aarsland, Laura Bonanni, Fabrizio Stocchi, Susanna Cordone, Görsev Yener, Carlo de Lena, Flavio Nobili, Peter Fuhr, Francesca De Pandis, Susanna Lopez, Claudio Babiloni, Heinrich Garn, Michela Pievani, Giovanni B. Frisoni, Fabrizia D'Antonio, Raffaele Ferri, Franco Giubilei, Erol Başar, Francesco Famà, Andrea Soricelli, Roberta Lizio, Ute Gschwandtner, Marco Onofrj, Claudio Del Percio, Paola Stirpe, Francesco Orzi, Gerhard Ransmayr, and Carla Buttinelli

Subjects
medicine.diagnostic_test, Epidemiology, Health Policy, Electroencephalography, Neural synchronization, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, medicine, Neurology (clinical), Geriatrics and Gerontology, Cognitive impairment, Psychology, Neuroscience
Published
2017
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30. [IC‐P‐173]: NON‐INVASIVE BRAIN MODULATION OF ABERRANT NETWORKS IN ALZHEIMER's DISEASE

Author

Rosa Manenti, Lorenzo Pini, Ilaria Boscolo Galazzo, Clarissa Ferrari, Michela Pievani, Giovanni B. Frisoni, Chiara Cobelli, Francesca B. Pizzini, and Maria Cotelli

Subjects
Epidemiology, business.industry, Health Policy, Non invasive, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Modulation, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Neuroscience
Published
2017
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31. [P2–357]: POSTOPERATIVE DELIRIUM IS ASSOCIATED WITH MARKERS OF NEURODEGENERATION BUT NO BRAIN AMYLOIDOSIS

Author

Michela Pievani, Giovanni B. Frisoni, Enrica Cavedo, Ugo Paolo Guerra, Giorgio Annoni, Mirko Patassini, Luca Matascioli, Elena Rolandi, Colm Cunningham, Samantha Galluzzi, Sabrina Morzenti, Christopher Buckley, Simone Franzoni, Monica Musarra, Lucio Carnevali, Flavio Terragnoli, Giuseppe Bellelli, Silvia Magnaldi, and Federica Ribaldi

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Amyloidosis, Neurodegeneration, medicine.disease, Gastroenterology, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Internal medicine, Medicine, Postoperative delirium, Neurology (clinical), Geriatrics and Gerontology, business
Published
2017
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32. P2‐370: AMYLOID‐PET FOR MYELIN IMAGING IN ALZHEIMER'S DISEASE

Author

Ribaldi, Federica, primary, Merlin, Giulia, additional, Marizzoni, Moira, additional, Garibotto, Valentina, additional, Andryszak, Paulina, additional, Tarallo, Anna, additional, Savelli, Giordano, additional, Guerra, Ugo Paolo, additional, Assal, Frederic, additional, Mendes, Aline, additional, Pievani, Michela, additional, and Frisoni, Giovanni B., additional

Published
2018
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33. P1‐395: FUNCTIONAL NETWORK CONNECTIVITY CHANGES IN EARLY AND LATE ONSET ALZHEIMER'S DISEASE

Author

Pini, Lorenzo, primary, Geroldi, Cristina, additional, Baruzzi, Roberta, additional, Galluzzi, Samantha, additional, Bertocchi, Monica, additional, Chitò, Eugenia, additional, Orini, Stefania, additional, Cotelli, Maria, additional, Cobelli, Milena, additional, Archetti, Silvana, additional, Zanetti, Orazio, additional, Frisoni, Giovanni B., additional, and Pievani, Michela, additional

Published
2018
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34. IC‐P‐040: FUNCTIONAL NETWORK CONNECTIVITY CHANGES IN EARLY AND LATE ONSET ALZHEIMER'S DISEASE

Author

Pini, Lorenzo, primary, Geroldi, Cristina, additional, Baruzzi, Roberta, additional, Galluzzi, Samantha, additional, Bertocchi, Monica, additional, Chitò, Eugenia, additional, Orini, Stefania, additional, Cotelli, Maria, additional, Cobelli, Milena, additional, Archetti, Silvana, additional, Zanetti, Orazio, additional, Frisoni, Giovanni B., additional, and Pievani, Michela, additional

Published
2018
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35. IC‐P‐122: Structural and Diffusion Tensor Imaging in MCI Subjects With Intermediate Risk of Alzheimer’s Disease Based on CSF Profile

Author

Olivier Blin, Moira Marizzoni, Diego Albani, Régis Bordet, Jean-Philippe Ranjeva, Michela Pievani, Giovanni B. Frisoni, Jorge Jovicich, Magda Tsolaki, Peter Schönknech, Lorenzo Pini, Gianluigi Forloni, David Bartrés-Faz, Pierre Payoux, Paolo Maria Rossini, Flavio Nobili, Pieter Jelle Visser, Andrea Soricelli, Jill C. Richardson, Lucilla Parnetti, Alberto Beltramello, Ute Fiedler, and Massimo Caulo

Subjects
Epidemiology, business.industry, Health Policy, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Nuclear magnetic resonance, Developmental Neuroscience, Medicine, Neurology (clinical), Geriatrics and Gerontology, Intermediate risk, business, Diffusion MRI
Published
2016
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36. P2‐263: Association between Brain MRI Diffusion Alterations and CSF Biomarkers in Amnestic MCI

Author

Jean-Philippe Ranjeva, Lorenzo Pini, David Bartrés-Faz, Flavio Nobili, Moira Marizzoni, Jorge Jovicich, and Michela Pievani

Subjects
0301 basic medicine, Pathology, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, 03 medical and health sciences, Psychiatry and Mental health, Cellular and Molecular Neuroscience, 030104 developmental biology, 0302 clinical medicine, Developmental Neuroscience, Csf biomarkers, Brain mri, medicine, Neurology (clinical), Geriatrics and Gerontology, Diffusion (business), business, 030217 neurology & neurosurgery
Published
2016
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37. [P2-357]: POSTOPERATIVE DELIRIUM IS ASSOCIATED WITH MARKERS OF NEURODEGENERATION BUT NO BRAIN AMYLOIDOSIS

Author

Rolandi, Elena, primary, Cavedo, Enrica, additional, Pievani, Michela, additional, Galluzzi, Samantha, additional, Ribaldi, Federica, additional, Buckley, Chris J., additional, Cunningham, Colm, additional, Guerra, Ugo Paolo, additional, Musarra, Monica, additional, Morzenti, Sabrina, additional, Magnaldi, Silvia, additional, Patassini, Mirko, additional, Terragnoli, Flavio, additional, Matascioli, Luca, additional, Franzoni, Simone, additional, Annoni, Giorgio, additional, Carnevali, Lucio, additional, Bellelli, Giuseppe, additional, and Frisoni, Giovanni B., additional

Published
2017
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39. [IC-P-174]: NETWORK-BASED MODULATION OF CEREBRAL PERFUSION AND FUNCTIONAL CONNECTIVITY IN ALZHEIMER's DISEASE

Author

Galazzo, Ilaria Boscolo, primary, Pizzini, Francesca B., additional, Pini, Lorenzo, additional, Ferrari, Clarissa, additional, Cobelli, Chiara, additional, Menegaz, Gloria, additional, Ciceri, Elisa M., additional, Cotelli, Maria, additional, Manenti, Rosa, additional, Frisoni, Giovanni B., additional, and Pievani, Michela, additional

Published
2017
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41. [P3-199]: ABNORMALITIES OF CORTICAL NEURAL SYNCHRONIZATION MECHANISMS IN SUBJECTS WITH MILD COGNITIVE IMPAIRMENT DUE TO ALZHEIMER's AND PARKINSON's DISEASES: AN EEG STUDY

Author

Lizio, Roberta, primary, Del Percio, Claudio, additional, Cordone, Susanna, additional, Lopez, Susanna, additional, Soricelli, Andrea, additional, Ferri, Raffaele, additional, Nobili, Flavio, additional, Famà, Francesco, additional, Aarsland, Dag, additional, Orzi, Francesco, additional, Buttinelli, Carla, additional, Giubilei, Franco, additional, Onofrj, Marco, additional, Stocchi, Fabrizio, additional, Stirpe, Paola, additional, Fuhr, Peter, additional, Gschwandtner, Ute, additional, Ransmayr, Gerhard, additional, Garn, Heinrich, additional, Pievani, Michela, additional, Frisoni, Giovanni B., additional, D'Antonio, Fabrizia, additional, de Lena, Carlo, additional, Başar, Erol, additional, Yener, Görsev, additional, Bonanni, Laura, additional, De Pandis, Francesca, additional, and Babiloni, Claudio, additional

Published
2017
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43. P4‐250: Appraisal of the utility of the amyloid imaging taskforce recommendations for amyloid‐PET prescription

Author

Patrizio Pasqualetti, Michela Pievani, Cristina Muscio, Giovanni B. Frisoni, Alessandro Padovani, Cristina Festari, Marina Boccardi, Emiliano Albanese, Flavio Nobili, Daniele Altomare, and Ugo Paolo Guerra

Subjects
Oncology, medicine.medical_specialty, Amyloid, Epidemiology, business.industry, Health Policy, Amyloid pet, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Internal medicine, medicine, Neurology (clinical), Geriatrics and Gerontology, Medical prescription, business
Published
2015
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44. P2‐158: The incremental diagnostic value of 18F‐florbetapir imaging in naturalistic patients with cognitive impairment: The India‐FBP study

Author

Michela Pievani, Cristina Muscio, Giovanni B. Frisoni, Ugo Paolo Guerra, Cristina Festari, Claudio Pizzocaro, Barbara Paghera, Marina Boccardi, Daniele Altomare, Anna Tarallo, and Alessandro Padovani

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, medicine.medical_specialty, Developmental Neuroscience, Epidemiology, Health Policy, medicine, Neurology (clinical), Geriatrics and Gerontology, Audiology, Cognitive impairment, Psychology, Value (mathematics)
Published
2015
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45. P4‐074: ITALIAN NETWORK FOR AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE AND FRONTOTEMPORAL LOBAR DEGENERATION (ITALIANDIAFN)

Author

Alessandro Padovani, Giuseppe Di Fede, Elio Scarpini, Martina Bocchetta, Emilio Di Maria, Giacomina Rossi, Silvia Suardi, Giuliano Binetti, Massimo Gennarelli, Daniela Galimberti, Livia Bernardi, Fabrizio Vecchio, Barbara Borroni, Benedetta Nacmias, Luisa Benussi, Anna Mega, Claudio Babiloni, Fabrizio Tagliavini, Amalia C. Bruni, Irene Piaceri, Corinna Porteri, Michela Pievani, Giovanni B. Frisoni, Roberta Ghidoni, Sandro Sorbi, Nicola Marzano, and Silvia Fostinelli

Subjects
Epidemiology, Health Policy, media_common.quotation_subject, Frontotemporal lobar degeneration, Art, medicine.disease, Associative learning, Right frontal lobe, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, medicine, Neurology (clinical), Geriatrics and Gerontology, Right hemisphere, Humanities, media_common
Abstract

Diffusion datasets were corrected for motion and eddy current distortions (Smith et al., 2004) and then processed with a Spherical Deconvolution algorithm based on a damped version of the Richardson-Lucy algorithm (Dell’acqua et al., 2010, Dell’Acqua et al., 2013). Tractography was performed following the method described in (Catani et al., 2012). We dissected fiftyfive frontal tracts including U-shaped fibers. For each dissection FA (Basser and Pierpaoli, 1996) and hindrance modulated oriented anisotropy (HMOA) (Dell’Acqua et al., 2013) were extracted as an indirect measure of the tract integrity and correlated with the age of the participants regressing out the level of education. P values are presented after false discovery rate (FDR) correction for multiple comparisons (* p < 0.05 ; ** p < 0.01 ; *** p < 0.001). Results: Aging was significantly associated with a decrease of FA (r1⁄4 0.501*) and OA (r1⁄4 0.508**) in the frontal projections of the corpus callosum. Aging was also associated with a decrease of OA in the right frontal lobe including the SLF I (r 1⁄4 0.401**) and SLF III (r 1⁄4 0.576***) branches of the superior longitudinal fasciculus, inferior fronto-occipital fasciculus (r 1⁄4 0.331*), fronto-thalamic projections (r 1⁄4 0.515***). In the left hemisphere, OA measure also decreased with aging for the frontal inferior longitudinal fasciculus (r1⁄4 0.542***) and the frontal orbito-polar tract (r 1⁄4 0.542***). Results are summarized in Figure 1. Conclusions: We confirmed preliminary evidences reporting reduced integrity in the frontal portion of the corpus callosum associated with aging (Lebel et al., 2010). This commissural decline may explain the increased reaction times associated with aging reported in tasks requiring interhemispheric transfer (Reuter-Lorenz and Stanczak, 2000). Our results also suggest for the first time that aging alters significantly other tracts in the right hemisphere which brings up interesting pathophysiological hypotheses for ageing decline in visuospatial and verbal working memory, memory encoding and retrieval, reward-based associative learning that can be tested in the elderly (Cabeza and Dennis, 2012). IC-P-069 ITALIAN NETWORK FOR AUTOSOMAL DOMINANTALZHEIMER’S DISEASE AND FRONTOTEMPORAL LOBAR DEGENERATION (ITALIANDIAFN) Martina Bocchetta, Michela Pievani, Claudio Babiloni, Amalia C. Bruni, Elio Scarpini, Sandro Sorbi, Fabrizio Tagliavini, Alessandro Padovani, Luisa Benussi, Livia Bernardi, Giuliano Binetti, Barbara Borroni, Giuseppe Di Fede, Emilio Di Maria, Silvia Fostinelli, Daniela Galimberti, Massimo Gennarelli, Roberta Ghidoni, Nicola Marzano, Anna Mega, Benedetta Nacmias, Irene Piaceri, Corinna Porteri, Giacomina Rossi, Silvia Suardi, Fabrizio Vecchio, Giovanni B. Frisoni, IRCCS Centro S. Giovanni di Dio, Fatebenefratelli, Brescia, Italy; IRCCS Fatebenefratelli, Brescia, Italy; 3 University of Rome "La Sapienza", Rome, Italy; 4 Centro Regionale di Neurogenetica, Lamezia Terme (CZ), Italy; 5 Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy; University of Florence, Florence, Italy; IRCCS Foundation "Carlo Besta" Neurological Institute, Milano, Italy; 8 University of Brescia, Brescia, Italy; 9 IRCCS Instituto Centro S. Giovanni di Dio Fatebenefratelli, Brescia, Italy; 10 Centro Regionale di Neurogenetica, Lamezia Terme, Italy; IRCCS Foundation "Carlo Besta" Neurological Institute, Milan, Italy; University of Genova, Genova, Italy; 13 IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy; University of Milan, Ospedale Policlinico, Milan, Italy; IRCCS Centro San Giovanni di Dio, Fatebenefratelli, Brescia, Italy; 16 University of Florence, Florence, Italy; 17 IRCCS Fondazione Instituto Neurologico Carlo Besta, Milano, Italy; 18 IRCCS Fondazione Instituto Neurologico Carlo Besta, Milan, Italy; IRCCS Instituto San Giovanni di Dio Fatebenefratelli, Brecia, Italy. Contact e-mail: mbocchetta@ fatebenefratelli.it

Published
2014
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46. IC‐P‐002: DEMENTIA EXPERTS' PERCEIVED DIAGNOSTIC VALUE OF PET AMYLOID IMAGING

Author

Michela Pievani, Cristina Muscio, Giovanni B. Frisoni, Patrizio Pasqualetti, Alessandro Padovani, Samantha Galluzzi, Marina Boccardi, and Barbara Borroni

Subjects
Oncology, medicine.medical_specialty, Amyloid, Epidemiology, business.industry, Health Policy, medicine.disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Internal medicine, medicine, Dementia, Neurology (clinical), Geriatrics and Gerontology, Psychiatry, business, Value (mathematics)
Published
2014
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47. P1‐172: THE INCREMENTAL DIAGNOSTIC VALUE OF 18F‐FLORBETAPIR IMAGING IN NATURALISTIC PATIENTS WITH COGNITIVE IMPAIRMENT: THE INDIA‐FBP STUDY

Author

Cristina Muscio, Marina Boccardi, Ugo Paolo Guerra, Barbara Paghera, Claudio Pizzocaro, Michela Pievani, Alessandro Padovani, and Giovanni Frisoni

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2014
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48. IC‐P‐069: ITALIAN NETWORK FOR AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE AND FRONTOTEMPORAL LOBAR DEGENERATION (ITALIANDIAFN)

Author

Martina Bocchetta, Michela Pievani, Claudio Babiloni, Amalia C. Bruni, Elio Scarpini, Sandro Sorbi, Fabrizio Tagliavini, Alessandro Padovani, Luisa Benussi, Livia Bernardi, Giuliano Binetti, Barbara Borroni, Giuseppe Di Fede, Emilio Di Maria, Silvia Fostinelli, Daniela Galimberti, Massimo Gennarelli, Roberta Ghidoni, Nicola Marzano, Anna Mega, Benedetta Nacmias, Irene Piaceri, Corinna Porteri, Giacomina Rossi, Silvia Suardi, Fabrizio Vecchio, and Giovanni B. Frisoni

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2014
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49. THE INCREMENTAL DIAGNOSTIC VALUE OF 18F‐FLORBETAPIR IMAGING IN NATURALISTIC PATIENTS WITH COGNITIVE IMPAIRMENT: THE INDIA‐FBP STUDY

Author

Ugo Paolo Guerra, Alessandro Padovani, Claudio Pizzocaro, Barbara Paghera, Marina Boccardi, Michela Pievani, Cristina Muscio, and Giovanni B. Frisoni

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology, Cognitive impairment, Psychology, Value (mathematics), Social psychology, Clinical psychology
Published
2014
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