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10 results on '"Lukas Scheef"'

1. IC-P-028: PATTERNS OF INCREASED AND DECREASED PRECUNEUS FUNCTIONAL CONNECTIVITY IN SCD DEPENDING ON AMYLOID STATUS

Author

Frank Jessen, Oliver Peters, Axel Rominger, Stefan J. Teipel, Bernd J. Krause, Markus Essler, Marcel Daamen, Lukas Scheef, Anja Schneider, Klaus Fließbach, Ralph Buchert, Shumei Li, Emrah Düzel, Henning Boecker, Katharina Buerger, Florian Gaertner, Annika Spottke, Matthias Reimold, Holger Amthauer, and Christoph Laske

Subjects
Amyloid, Epidemiology, Chemistry, Health Policy, Functional connectivity, Precuneus, Psychiatry and Mental health, Cellular and Molecular Neuroscience, medicine.anatomical_structure, Developmental Neuroscience, medicine, Neurology (clinical), Geriatrics and Gerontology, Neuroscience
Published
2019
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2. P2-359: CORTICAL AMYLOID BURDEN CORRELATES WITH ATROPHY OF THE POSTERIOR PART OF THE NUCLEUS BASALIS MEYNERT IN AMYLOID-POSITIVE SCD

Author

Oliver Peters, Markus Essler, Klaus Fliessbach, Marcel Daamen, Bernd J. Krause, Annika Spottke, Axel Rominger, Florian Gaertner, Anja Schneider, Michel J. Grothe, Matthias Reimold, Lukas Scheef, Ralph Buchert, Emrah Düzel, Shumei Li, Katharina Buerger, Stefan J. Teipel, Frank Jessen, Henning Boecker, Holger Amthauer, and Christoph Laske

Subjects
Pathology, medicine.medical_specialty, Amyloid, Epidemiology, business.industry, Health Policy, Nucleus basalis, medicine.disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Atrophy, Developmental Neuroscience, Medicine, Amyloid burden, Neurology (clinical), Geriatrics and Gerontology, business
Published
2019
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3. IC-P-016: CORTICAL AMYLOID BURDEN CORRELATES WITH ATROPHY OF THE POSTERIOR PART OF THE NUCLEUS BASALIS MEYNERT IN AMYLOID-POSITIVE SCD

Author

Lukas Scheef, Marcel Daamen, Michel J. Grothe, Shumei Li, Florian Gaertner, Oliver Peters, Holger Amthauer, Ralph Buchert, Katharina Buerger, Axel Rominger, Stefan J. Teipel, Bernd J. Krause, Klaus Fliessbach, Anja Schneider, Markus Essler, Christoph Laske, Matthias Reimold, Annika Spottke, Emrah Düzel, Frank Jessen, and Henning Boecker

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2019
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4. Gray matter atrophy pattern in elderly with subjective memory impairment

Author

Michael Wagner, Frank Jessen, Jessica Peter, Ahmed Abdulkadir, Michael T. Heneka, Stefan Klöppel, Lukas Scheef, Alexander Koppara, and Henning Boecker

Subjects
Male, medicine.medical_specialty, Support Vector Machine, Epidemiology, education, Neuropsychological Tests, Audiology, Developmental psychology, Cellular and Molecular Neuroscience, Imaging, Three-Dimensional, Developmental Neuroscience, pathology [Brain], mental disorders, medicine, Humans, Dementia, pathology [Memory Disorders], ddc:610, Longitudinal Studies, Effects of sleep deprivation on cognitive performance, Cognitive decline, Episodic memory, Aged, etiology [Atrophy], diagnosis [Cognition Disorders], Cerebral atrophy, Memory Disorders, pathology [Atrophy], Health Policy, fungi, Brain, etiology [Cognition Disorders], Cognition, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Cognitive test, Psychiatry and Mental health, Cross-Sectional Studies, ROC Curve, Female, Neurology (clinical), Atrophy, complications [Memory Disorders], Geriatrics and Gerontology, Cognition Disorders, Psychology, Alzheimer's Disease Neuroimaging Initiative
Abstract

Background Individuals with subjective memory impairment (SMI) report worsening of memory without impairment in cognitive tests. Despite normal cognitive performance, they may be at higher risk of cognitive decline compared with individuals without SMI. Methods We used a discriminative function (a support vector machine) trained on an independent data set of 226 healthy control subjects and 191 patients with probable Alzheimer's disease (AD) dementia to characterize the baseline gray matter patterns of 24 individuals with SMI and 53 control subjects. We tested for associations of these gray matter patterns with SMI presence, cognitive performance at baseline, and cognitive decline at follow-up. Results Individuals with SMI showed greater similarity to an AD gray matter pattern compared with control subjects without SMI. In addition, episodic memory decline was associated with an AD gray matter pattern in the SMI group. Conclusions Our results indicate a link between the gray matter atrophy pattern of patients with AD and the presence of SMI. Furthermore, multivariate pattern recognition approaches seem to be a sensitive method for identifying subtle brain changes that correspond to future memory decline in SMI.

Published
2013
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5. P1‐018: HIPPOCAMPAL GREY MATTER ATROPHY IS ASSOCIATED WITH THE FREE AND CUED SELECTIVE REMINDING TEST

Author

Eva Burkei, Dix Meiberth, Ingo Frommann, Frank Jessen, Wolfgang Block, Lukas Scheef, Xiaochen Hu, Michael T. Heneka, Michael Wagner, Hans H. Schild, and Sandra Röske

Subjects
Cued speech, Grey matter atrophy, Epidemiology, Health Policy, Hippocampal formation, Test (assessment), Developmental psychology, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Neurology (clinical), Geriatrics and Gerontology, Psychology, Neuroscience
Published
2014
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6. IC‐P‐163: HIPPOCAMPAL GREY MATTER ATROPHY IS ASSOCIATED WITH THE FREE AND CUED SELECTIVE REMINDING TEST

Author

Dix Meiberth, Eva Burkei, Wolfgang Block, Lukas Scheef, Hans H. Schild, Michael T. Heneka, Michael Wagner, Ingo Frommann, Sandra Röske, Xiaochen Hu, and Frank Jessen

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2014
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7. IC‐P‐122: Cortical thinning in subjective memory impairment

Author

Frank Jessen, Lukas Scheef, Dix Meiberth, and Henning Boecker

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, medicine.medical_specialty, Developmental Neuroscience, Epidemiology, Health Policy, medicine, Cortical thinning, Neurology (clinical), Subjective memory, Geriatrics and Gerontology, Audiology, Psychology
Published
2013
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10. P‐129: Cognitive performance and grey matter structure in elderly with subjective memory impairment

Author

Karsten Schaper, Frank Jessen, Michael Wagner, and Lukas Scheef

Subjects
Structure (mathematical logic), Epidemiology, Health Policy, Subjective memory, Grey matter, Psychiatry and Mental health, Cellular and Molecular Neuroscience, medicine.anatomical_structure, Developmental Neuroscience, medicine, Neurology (clinical), Effects of sleep deprivation on cognitive performance, Geriatrics and Gerontology, Psychology, Cognitive psychology
Published
2007
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