1. World‐Wide FINGERS Network: A global approach to risk reduction and prevention of dementia
- Author
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Kivipelto, Miia, Mangialasche, Francesca, Snyder, Heather M, Allegri, Ricardo, Andrieu, Sandrine, Arai, Hidenori, Baker, Laura, Belleville, Sylvie, Brodaty, Henry, Brucki, Sonia M, Calandri, Ismael, Caramelli, Paulo, Chen, Christopher, Chertkow, Howard, Chew, Effie, Choi, Seong H, Chowdhary, Neerja, Crivelli, Lucía, De La Torre, Rafael, Du, Yifeng, Dua, Tarun, Espeland, Mark, Feldman, Howard H, Hartmanis, Maris, Hartmann, Tobias, Heffernan, Megan, Henry, Christiani J, Hong, Chang H, Håkansson, Krister, Iwatsubo, Takeshi, Jeong, Jee H, Jimenez‐Maggiora, Gustavo, Koo, Edward H, Launer, Lenore J, Lehtisalo, Jenni, Lopera, Francisco, Martínez‐Lage, Pablo, Martins, Ralph, Middleton, Lefkos, Molinuevo, José L, Montero‐Odasso, Manuel, Moon, So Y, Morales‐Pérez, Kristal, Nitrini, Ricardo, Nygaard, Haakon B, Park, Yoo K, Peltonen, Markku, Qiu, Chengxuan, Quiroz, Yakeel T, Raman, Rema, Rao, Naren, Ravindranath, Vijayalakshmi, Rosenberg, Anna, Sakurai, Takashi, Salinas, Rosa M, Scheltens, Philip, Sevlever, Gustavo, Soininen, Hilkka, Sosa, Ana L, Suemoto, Claudia K, Tainta‐Cuezva, Mikel, Velilla, Lina, Wang, Yongxiang, Whitmer, Rachel, Xu, Xin, Bain, Lisa J, Solomon, Alina, Ngandu, Tiia, and Carrillo, Maria C
- Subjects
Dementia ,Clinical Research ,Neurosciences ,Behavioral and Social Science ,Aging ,Prevention ,Alzheimer's Disease ,Neurodegenerative ,Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) ,Brain Disorders ,Acquired Cognitive Impairment ,3.1 Primary prevention interventions to modify behaviours or promote wellbeing ,Prevention of disease and conditions ,and promotion of well-being ,Neurological ,Alzheimer Disease ,Clinical Trials as Topic ,Cognition ,Exercise Therapy ,Humans ,Life Style ,Research Design ,Risk Reduction Behavior ,Alzheimer's disease ,cognitive impairment ,dementia ,lifestyle ,multidomain intervention ,prevention ,randomized controlled trial ,World-Wide FINGERS ,Clinical Sciences ,Geriatrics - Abstract
Reducing the risk of dementia can halt the worldwide increase of affected people. The multifactorial and heterogeneous nature of late-onset dementia, including Alzheimer's disease (AD), indicates a potential impact of multidomain lifestyle interventions on risk reduction. The positive results of the landmark multidomain Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) support such an approach. The World-Wide FINGERS (WW-FINGERS), launched in 2017 and including over 25 countries, is the first global network of multidomain lifestyle intervention trials for dementia risk reduction and prevention. WW-FINGERS aims to adapt, test, and optimize the FINGER model to reduce risk across the spectrum of cognitive decline-from at-risk asymptomatic states to early symptomatic stages-in different geographical, cultural, and economic settings. WW-FINGERS aims to harmonize and adapt multidomain interventions across various countries and settings, to facilitate data sharing and analysis across studies, and to promote international joint initiatives to identify globally implementable and effective preventive strategies.
- Published
- 2020