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Start Over Author "Hieab H.H. Adams" Journal alzheimer's & dementia
22 results on '"Hieab H.H. Adams"'

1. Epigenome‐wide association study and integrative cross‐omics analyses of cerebral white matter hyperintensities implicate novel gene networks related to Alzheimer’s disease

Author

Yunju Yang, Qiong Yang, Maria J. Knol, Aniket Mishra, Nicola Armstrong, Hieab H.H. Adams, Jennifer A Smith, Monique M.B. Breteler, Hans J. Grabe, Joanna M Wardlaw, Lenore J. Launer, William T Longstreth, Sudha Seshadri, Stéphanie Debette, and Myriam Fornage

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2022
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2. Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease

Author

Marie‐Gabrielle Duperron, Maria J. Knol, Quentin Le Grand, Tavia E Evans, Aniket Mishra, Gennady V. Roshchupkin, Takahiro Konuma, David Alexandre Tregouët, Jose Rafael Romero, Stefan Frenzel, Michelle Luciano, Edith Hofer, Mathieu Bourgey, Nicole D Dueker, Pilar Delgado, Saima Hilal, Rick M. Tankard, Florian Dubost, Jean Shin, Yasaman Saba, Christopher Chen, Tatjana Rundek, Alexander Teumer, Ami Tsuchida, Helena Schmidt, Perminder S. Sachdev, Wei Wen, Anne Joutel, Claudia L Satizabal, Ralph Sacco, Guillaume Bourque, Mark Lathrop, Tomas Paus, Israel Fernandez‐Cadenas, Bernard Mazoyer, Yukinori Okada, Hans J. Grabe, Karen A Mather, Reinhold Schmidt, M. Arfan Ikram, Christophe Tzourio, Joanna M Wardlaw, Sudha Seshadri, Hieab H.H. Adams, and Stéphanie Debette

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2022
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5. Circulating metabolites are associated with brain atrophy and white matter hyperintensities

Author

Frederik Barkhof, Thomas Hankemeier, Philip Scheltens, Aad van der Lugt, Cornelia M. van Duijn, Carel F.W. Peeters, Francisca A. de Leeuw, M. Arfan Ikram, Dina Vojinovic, Najaf Amin, Hieab H.H. Adams, Charlotte E. Teunissen, Daniel Bos, Shahzad Ahmad, Meike W. Vernooij, Betty M. Tijms, Wiesje M. van der Flier, Maartje I. Kester, Hata Karamujić-Čomić, Neurology, Amsterdam Neuroscience - Neurodegeneration, Amsterdam Neuroscience - Brain Imaging, Epidemiology and Data Science, Radiology and nuclear medicine, Amsterdam Neuroscience - Cellular & Molecular Mechanisms, Amsterdam Neuroscience - Neuroinfection & -inflammation, Laboratory Medicine, APH - Methodology, APH - Personalized Medicine, Epidemiology, Clinical Genetics, and Radiology & Nuclear Medicine

Subjects
Blood Glucose, Male, magnetic resonance imaging (MRI), Epidemiology, Hippocampus, chemistry.chemical_compound, 0302 clinical medicine, High-density lipoprotein, 030212 general & internal medicine, HDL particle, glucose, medicine.diagnostic_test, Health Policy, Brain, Alzheimer's disease, Middle Aged, Magnetic Resonance Imaging, White Matter, Hippocampal atrophy, 3. Good health, Psychiatry and Mental health, Female, medicine.medical_specialty, Intervention trials, lipids, 03 medical and health sciences, Cellular and Molecular Neuroscience, Atrophy, SDG 3 - Good Health and Well-being, Developmental Neuroscience, Alzheimer Disease, Internal medicine, medicine, Humans, Aged, Featured Articles, business.industry, Cholesterol, cholesterol, Magnetic resonance imaging, Featured Article, medicine.disease, Hyperintensity, Endocrinology, chemistry, Neurology (clinical), Geriatrics and Gerontology, business, metabolism, 030217 neurology & neurosurgery
Abstract

Introduction: Our aim was to study whether systemic metabolites are associated with magnetic resonance imaging (MRI) measures of brain and hippocampal atrophy and white matter hyperintensities (WMH). Methods: We studied associations of 143 plasma-based metabolites with MRI measures of brain and hippocampal atrophy and WMH in three independent cohorts (n = 3962). We meta-analyzed the results of linear regression analyses to determine the association of metabolites with MRI measures. Results: Higher glucose levels and lower levels of three small high density lipoprotein (HDL) particles were associated with brain atrophy. Higher glucose levels were associated with WMH. Discussion: Glucose levels were associated with brain atrophy and WMH, and small HDL particle levels were associated with brain atrophy. Circulating metabolites may aid in developing future intervention trials.

Published
2021
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6. P3‐134: CIRCULATING METABOLITES ARE ASSOCIATED WITH WHITE MATTER HYPERINTENSITIES

Author

Hata Karamujić-Čomić, Shahzad Ahmad, M. Arfan Ikram, Daniel Bos, Wiesje M. Flier, Meike W. Vernooij, Aad van der Lugt, Cornelia M. van Duijn, Hieab H.H. Adams, Dina Vojinovic, Najaf Amin, and Thomas Hankemeier

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Pathology, medicine.medical_specialty, Developmental Neuroscience, Epidemiology, business.industry, Health Policy, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Hyperintensity
Published
2018
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7. P4‐042: HIGH‐DIMENSIONAL ANALYSIS OF RNA EXPRESSION WITH CORTICAL THICKNESS

Author

Gennady V. Roshchupkin, Ryan L. Muetzel, Maria J. Knol, Meike W. Vernooij, Hieab H.H. Adams, Cornelia M. van Duijn, and M. Arfan Ikram

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Rna expression, Developmental Neuroscience, Epidemiology, Chemistry, Health Policy, Biophysics, Neurology (clinical), High dimensional, Geriatrics and Gerontology
Published
2018
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8. O5‐04‐05: GENETIC VARIATION UNDERLYING COGNITION AND ITS RELATION WITH NEUROLOGICAL OUTCOMES

Author

André G. Uitterlinden, Wiro J. Niessen, Meike W. Vernooij, Hieab H.H. Adams, M. Arfan Ikram, Cornelia M. van Duijn, Lotte G.M. Cremers, Alis Heshmatollah, M. Kamran Ikram, and Maria J. Knol

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Genetic variation, Cognition, Neurology (clinical), Geriatrics and Gerontology, Relation (history of concept), Psychology, Cognitive psychology
Published
2018
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9. O2-02-05: PREDICTING BRAIN AGE AS A BIOMARKER FOR RISK OF DEMENTIA

Author

Maria J. Knol, Wiro J. Niessen, Aleksei Tiulpin, Gennady V. Roshchupkin, Meike W. Vernooij, Hieab H.H. Adams, Marleen de Bruijne, Johnny Wang, M. Arfan Ikram, and Florian Dubost

Subjects
Oncology, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, medicine.disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Internal medicine, medicine, Dementia, Biomarker (medicine), Neurology (clinical), Geriatrics and Gerontology, business
Published
2019
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10. IC-P-036: THE UNITED CONSORTIUM: CLINICAL APPLICATIONS OF HIGH-DIMENSIONAL NEUROIMAGING DATA IN AN ETHNICALLY DIVERSE SETTING

Author

Tavia E. Evans, Natalie Terzikhan, and Hieab H.H. Adams

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Neuroimaging, Epidemiology, Health Policy, Neurology (clinical), High dimensional, Geriatrics and Gerontology, Ethnically diverse, Psychology, Clinical psychology
Published
2019
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11. [P1–139]: PATHWAY‐SPECIFIC GENETIC RISK SCORE ASSOCIATED WITH ALZHEIMER's DISEASE AND WHITE MATTER LESIONS IN COGNITIVELY NORMAL SUBJECTS

Author

M. Arfan Ikram, Cornelia M. van Duijn, Meike W. Vernooij, Rebecca Sims, Valentina Escott-Price, Alfredo Ramirez, Shahzad Ahmad, Dina Vojinovic, Najaf Amin, Sven J. van der Lee, Peter Holmans, Hieab H.H. Adams, and Christian Bannister

Subjects
Gerontology, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Disease, Geriatrics and Gerontology, Genetic risk, Psychology, Hyperintensity, Clinical psychology
Published
2017
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12. [P1–442]: SHAPE OF SUBCORTICAL BRAIN STRUCTURES AND THE RISK OF DEMENTIA: THE ROTTERDAM STUDY

Author

Hieab H.H. Adams, Vanja Vlasov, Gennady V. Roshchupkin, Kamran M. Ikram, M. Arfan Ikram, Boris A. Gutman, and Meike W. Vernooij

Subjects
Gerontology, medicine.medical_specialty, Epidemiology, Health Policy, medicine.disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Rotterdam Study, Developmental Neuroscience, medicine, Dementia, Neurology (clinical), Geriatrics and Gerontology, Psychiatry, Psychology
Published
2017
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13. P2‐268: Hippocampal Subfields Provide Information Beyond Gross Volume for Cognition and Risk of Dementia

Author

Meike W. Vernooij, M. Arfan Ikram, Hieab H.H. Adams, and Tavia E. Evans

Subjects
Epidemiology, Health Policy, Cognition, Hippocampal formation, medicine.disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, medicine, Dementia, Neurology (clinical), Geriatrics and Gerontology, Psychology, Cognitive psychology, Volume (compression)
Published
2016
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14. O2‐10‐02: Genetic Determinants of MRI Subcortical Brain Structures: 24 Novel Loci Identified Through Gwas in 26,000 Persons

Author

M. Schroeter, Paul M. Thompson, Ian J. Deary, Claudia L. Satizabal, Stéphanie Debette, Mohammad Kamran Ikram, Derrek P. Hibar, Hieab H.H. Adams, Cornelia M. van Duijn, Sudha Seshadri, Lenore J. Launer, Myriam Fornage, M. Arfan Ikram, Reinhold Schmidt, and David A. Bennett

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Genome-wide association study, Neurology (clinical), Computational biology, Geriatrics and Gerontology, Biology
Published
2016
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15. O3‐03‐06: Grey Matter Density in Relation to Cognitive Function

Author

Hieab H.H. Adams, M. Arfan Ikram, Hazel I. Zonneveld, Gennady V. Roshchupkin, Wiro J. Niessen, and Meike W. Vernooij

Subjects
Relation (database), Epidemiology, Health Policy, Cognition, Grey matter, Psychiatry and Mental health, Cellular and Molecular Neuroscience, medicine.anatomical_structure, Developmental Neuroscience, medicine, Neurology (clinical), Geriatrics and Gerontology, Cognitive psychology, Mathematics
Published
2016
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16. P1‐276: Anterior Commissure: Neuroanatomic and Cognitive Correlates in a Population‐Based Study

Author

Hieab H.H. Adams, Wiro J. Niessen, Meike W. Vernooij, M. Arfan Ikram, and Gennady V. Roshchupkin

Subjects
Epidemiology, business.industry, Health Policy, Anterior commissure, Cognition, Anatomy, Population based study, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Medicine, Neurology (clinical), Geriatrics and Gerontology, business
Published
2016
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17. O4‐05‐02: Genome‐wide association study of lobar brain volumes

Author

Lisa R. Yanek, Christophe Tzourio, Bernard Mazoyer, Charles DeCarli, Lenore J. Launer, David A. Bennett, M. Arfan Ikram, Najaf Amin, Sven J. van der Lee, Sudha Seshadri, Qiong Yang, Lei Yu, Debra A. Fleischman, Stéphanie Debette, Konstantinos Arfanakis, Ganesh Chauhan, Shuo Li, Cornelia M. van Duijn, Edith Hofer, Hieab H.H. Adams, Albert V. Smith, Claudia L. Satizabal, Philip L. De Jager, and Vincent Chouraki

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Genome-wide association study, Neurology (clinical), Computational biology, Geriatrics and Gerontology, Biology
Published
2015
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18. O4‐05‐03: Whole exome sequence analysis of white matter hyperintensities on cranial MRI

Author

Hieab H.H. Adams, Anita L. DeStefano, Sudha Seshadri, Charles DeCarli, Xueqiu Jian, Myriam Fornage, Vincent Chouraki, Thomas H. Mosley, Cornelia M. van Duijn, Richard A. Gibbs, Eric Boerwinkle, M. Arfan Ikram, Bruce M. Psaty, Jennifer A. Brody, Joshua C. Bis, and W. T. Longstreth

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, business.industry, Health Policy, Medicine, Whole exome sequence analysis, Neurology (clinical), Anatomy, Geriatrics and Gerontology, business, Hyperintensity
Published
2015
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19. P3‐071: A GENOME‐WIDE META‐ANALYSIS OF PLASMA CLUSTERIN LEVELS IN THE CHARGE CONSORTIUM

Author

Vilmundur Gudnason, Sudha Seshadri, Daniel Levy, Veer Bala Gupta, Henry Brodaty, Lenore J. Launer, Richard Dobson, Jennifer Mollon, Gudny Eiriksdottir, Fei Song, Vincent Chouraki, Karen A. Mather, Mohammad Arfan Ikram, Madhav Thambisetty, Anbupalam Thalamuthu, John Attia, Liz Holliday, Perminder S. Sachdev, Toshiko Tanaka, Ralph N. Martins, Christopher Oldmeadow, Rodney J. Scott, Johanna Jakobsdottir, Hieab H.H. Adams, Simon Lovestone, and Anne Poljak

Subjects
Clusterin, biology, Epidemiology, Chemistry, Health Policy, Charge (physics), Plasma, Computational biology, Genome, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, biology.protein, Neurology (clinical), Geriatrics and Gerontology
Published
2014
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20. O4‐08‐03: GENETIC RISK OF NEURODEGENERATIVE DISEASES IS ASSOCIATED WITH MILD COGNITIVE IMPAIRMENT AND CONVERSION TO DEMENTIA: THE ROTTERDAM STUDY

Author

Meike W. Vernooij, Hieab H.H. Adams, Mohammad Arfan Ikram, Cornelia M. van Duijn, Peter J. Koudstaal, Albert Hofman, André G. Uitterlinden, and Renée F.A.G. de Bruijn

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, medicine.disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Rotterdam Study, Developmental Neuroscience, medicine, Dementia, Neurology (clinical), Geriatrics and Gerontology, Genetic risk, business, Psychiatry, Cognitive impairment
Published
2014
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21. P1‐270: DETERMINANTS OF ENLARGED VIRCHOW‐ROBIN SPACES: THE UNIVRSE CONSORTIUM

Author

Reinhold Schmidt, Mohammad Arfan Ikram, Petra Schwingenschuh, Meike W. Vernooij, Hieab H.H. Adams, Gabriel P. Krestin, Petra Katschnig-Winter, Albert Hofman, and Aad van der Lugt

Subjects
Epidemiology, Health Policy, media_common.quotation_subject, Art history, Virchow robin spaces, Art, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Center (algebra and category theory), Neurology (clinical), Geriatrics and Gerontology, Erasmus+, media_common
Abstract

ROBIN SPACES: THE UNIVRSE CONSORTIUM Hieab H.H. Adams, Petra Schwingenschuh, Aad van der Lugt, Petra Katschnig-Winter, Albert Hofman, Gabriel Krestin, Meike Vernooij, Reinhold Schmidt, Mohammad Arfan Ikram, Erasmus MC, Rotterdam, Netherlands; Medical University Graz, Graz, Austria; Erasmus Medical Center, Rotterdam, Netherlands; Medical University Graz, Graz, Austria. Contact e-mail: h.adams@erasmusmc.nl

Published
2014
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22. O4‐04‐05: ASSOCIATION OF ALZHEIMER DISEASE GWAS LOCI WITH MRI‐MARKERS OF BRAIN AGING

Author

Mohammad Arfan Ikram, Myriam Fornage, Joshua C. Bis, Lei Yu, James T. Becker, Meike W. Vernooij, Albert V. Smith, David S. Knopman, Hieab H.H. Adams, Philippe Amouyel, Velandai Srikanth, Thomas H. Mosley, Stéphanie Debette, Lenore J. Launer, Christophe Tzourio, Oscar L. Lopez, Sudha Seshadri, Cornelia M. van Duijn, Sven J. van der Lee, William T. Longstreth, Reinhold Schmidt, Galit Weinstein, Ganesh Chauhan, David A. Bennett, Charlie S. DeCarli, and Helena Schmidt

Subjects
Epidemiology, business.industry, Health Policy, Genome-wide association study, medicine.disease, Bioinformatics, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Medicine, Neurology (clinical), Geriatrics and Gerontology, Alzheimer's disease, business, Association (psychology), Brain aging
Published
2014
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