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Background: Previous research suggests that hypertension shape cognitive health outcomes in older Blacks (Whitfield 2008). However, few studies have explored the relation between objective and subjective blood pressure (BP) measures and cognitive decline. This study examined whether systolic, diastolic, and self‐reported BP were associated with changes in cognition. Method: Data are drawn from the Baltimore Study of Black Aging—Patterns of Cognitive Aging. At baseline, 602 Black participants (48‐95 years) were enrolled. At follow‐up, approximately 3 years later, 450 participants were re‐interviewed. Cognition included 5 domains: working memory, processing speed, verbal memory, vocabulary, and inductive reasoning. Using an oscillometer automated device (A&D model UA‐ 767), three readings of orthostatic BP were collected and mean systolic (SBP; range = 82‐230.3 mmHg) and diastolic BP (DBP; range = 51‐136.7 mmHg) values were calculated for each participant. BP was treated as a continuous variable. Participants were also asked "Have you ever been told by a doctor or nurse that you have high blood pressure? (yes/no response)" Data were analyzed using multiple linear regression, controlling for sociodemographic and health conditions. Result: Majority of the sample was female (25.4% male) and had at least a high school education (57.1%). Systolic BP was inversely associated with inductive reasoning at follow‐up (b = ‐0.208, p = 0.023; see Table 1), but was not related to any other cognitive domains, after adjusting for age, sex, education, depressive symptoms, comorbidities, diastolic BP, and baseline cognition. Diastolic BP and self‐reported hypertensive status were both unrelated to changes in each of the five cognitive domains (all models, p> 0.05). Conclusion: The present study adds to our understanding of cognitive aging among older Black Americans. Results support previous research, pointing to an independent effect of BP on domain‐specific cognitive changes (Buford 2016), but also extend the literature by highlighting a more pronounced negative effect of systolic BP. These findings suggest that the pathway to cognitive dysfunction is contributed to by BP. Several key mechanisms – including increased risk for stroke and "vascular dementia" (age‐ and hypertension‐related cerebral vasculature changes) – may explain the influence of hypertension on cognitive decline that warrant further study in Black Americans. [ABSTRACT FROM AUTHOR]

Background: Previous research suggests that chronic health conditions and financial hardship robustly shape cognitive health outcomes, including ADRD risk in older Blacks. However, few studies have explored the moderating effect of financial hardship on chronic disease burden and specific cognitive domains. This study examined whether financial hardship modifies the impact of self‐reported chronic health conditions on episodic memory among a representative sample of older Blacks enrolled in the 2006 Health and Retirement Study (HRS). Method: The study included 934 older Blacks (50+ years) who completed the psychosocial leave‐behind questionnaire in the 2006 wave of the HRS. Episodic memory included a composite standardized score of immediate and delayed recall. Six chronic health conditions (e.g., hypertension, diabetes, stroke) were summed and dichotomized (0‐1 vs. as ≥2 conditions). Financial hardship was assessed as self‐reported difficulty paying monthly bills (range: not at all=0 to very/completely=3). Weighted OLS regression models tested independent associations between chronic health conditions and episodic memory, controlling for sociodemographic characteristics. An interaction term tested moderation by financial hardship. Result: The majority of the sample was female (39.34% male) and had less than a high school education (35.89%; Table 1). Financial hardship modified the association between chronic disease burden and episodic memory performance such that individuals who reported very little difficulty paying their monthly bills had significantly lower memory scores at high levels of disease burden compared to those reporting high financial difficulty after controlling for age, gender, education and income (F 2, 49 = 4.97, p= 0.011; see Table 2 and Figure 1). Conclusion: The present study adds to our understanding of cognitive aging among older Black Americans. Results support previous research, pointing to the independent negative effects of both chronic diseases and subjective financial burden, but also extend the literature by suggesting an interactive effect. Specifically, multimorbidity was more strongly associated with worse episodic memory functioning among older Blacks with less financial hardship, which appeared to be driven by the relatively low cognitive functioning among those with the greatest financial hardship. This pattern of results suggest that financial hardship may be just as consequential for cognitive aging as chronic diseases for older Blacks. [ABSTRACT FROM AUTHOR]

Background: There has been sparse attention paid to the cognition of older men and potential race differences in cognitive ability among older men. Men's health disparities are likely to continue to increase in the next few decades, likely due to an aging baby boom cohort; increases in racial diversity in the US; and increases in life expectancy among both Black and White men. Our objective was to examine the completed cognitive intervention trials to ascertain the proportion of Black men and racial differences in such trials. Method: We conducted a scoping review of reported cognitive intervention trials between the years 2000 and 2020. We searched PubMed, Google Scholar, CINHAL, Cochrane, and Clinicaltrials.gov for cognitive intervention trials using the following MeSH terms – "cognitive intervention", "mild cognitive impairment", "dementia", "Alzheimer's disease", and "cognitive disorder". Inclusion criteria included U.S, based interventions intended to improve cognition. Result: We found 293 unique trials that met our search terms of which 66 were included for final analysis. The rest were excluded due to not being in the US, only including healthy participants, and use of non‐cognitive interventions. We were able to assess the number of Black men in 9 out of the 66 trials, because the trials were either all White (n=8) or all Black (n=1). Of the 9 trials we could assess, 8 had no Black participants (thus no Black men) and the one with all Black participants had 21% men. Of the remaining 57 trials, 32 did not report race and 25 included race and sex data but did not include race‐sex categories and thus we were unable to determine the number of black men included. Conclusion: We were unable to determine if cognitive intervention trials included sufficient proportions of Black men due to non‐reporting of race, race‐sex categories, and lack of inclusion of Black persons in trials. Our results beg the question of how we can understand cognitive health disparities and improve representation in trials if we don't include the information that would allow us to make that determination. [ABSTRACT FROM AUTHOR]