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Summary: Background: Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common cause of chronic liver disease. Its prevalence is increasing with the epidemic of obesity and metabolic syndrome. MASLD progression into metabolic dysfunction‐associated steatohepatitis (MASH) and advanced fibrosis may lead to decompensated cirrhosis and development of liver‐related events, hepatocellular carcinoma and death. Monitoring disease progression is critical in decreasing morbidity, mortality, need for transplant and economic burden. Assessing for treatment response once FDA‐approved medications are available is still an unmet clinical need. Aims: To explore the most up‐to‐date literature on testing used for monitoring disease progression and treatment response Methods: We searched PubMed from inception to 15 August 2023, using the following MeSH terms: 'MASLD', 'Metabolic dysfunction‐associated steatotic liver disease', 'MASH', 'metabolic dysfunction‐associated steatohepatitis', 'Non‐Alcoholic Fatty Liver Disease', 'NAFLD', 'non‐alcoholic steatohepatitis', 'NASH', 'Biomarkers', 'clinical trial'. Articles were also identified through searches of the authors' files. The final reference list was generated based on originality and relevance to this review's broad scope, considering only papers published in English. Results: We have cited 101 references in this review detailing methods to monitor MASLD disease progression and treatment response. Conclusion: Various biomarkers can be used in different care settings to monitor disease progression. Further research is needed to validate noninvasive tests more effectively. [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Yoon et al paper. To view this article, visit https://doi.org/10.1111/apt.17909 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Hong et al papers. To view these articles, visit https://doi.org/10.1111/apt.17819 and https://doi.org/10.1111/apt.17937 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Wu et al papers. To view these articles, visit https://doi.org/10.1111/apt.17667 and https://doi.org/10.1111/apt.17679 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Wu et al papers. To view these articles, visit https://doi.org/10.1111/apt.17667 and https://doi.org/10.1111/apt.17685 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Sharma et al papers. To view these articles, visit https://doi.org/10.1111/apt.16369 and https://doi.org/10.1111/apt.16910 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Cho et al papers. To view these articles, visit https://doi.org/10.1111/apt.17255 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Sharma et al papers. To view these articles, visit https://doi.org/10.1111/apt.16369 and https://doi.org/10.1111/apt.16877 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Panaccione et al papers. To view these articles, visit https://doi.org/10.1111/apt.16848 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Danese et al papers. To view these articles, visit https://doi.org/10.1111/apt.16753 and https://doi.org/10.1111/apt.16761 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Danese et al papers. To view these articles, visit https://doi.org/10.1111/apt.16753 and https://doi.org/10.1111/apt.16795 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Safadi et al papers. To view these articles, visit https://doi.org/10.1111/apt.16664 and https://doi.org/10.1111/apt.16748 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Safadi et al papers. To view these articles, visit https://doi.org/10.1111/apt.16664 and https://doi.org/10.1111/apt.16762 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Schultheiss et al papers. To view these articles, visit https://doi.org/10.1111/apt.16605 and https://doi.org/10.1111/apt.16757 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Zhao et al papers. To view these articles, visit https://doi.org/10.1111/apt.16723 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Sorda et al papers. To view these articles, visit https://doi.org/10.1111/apt.16618 and https://doi.org/10.1111/apt.16657 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Sorda et al papers. To view these articles, visit https://doi.org/10.1111/apt.16618 and https://doi.org/10.1111/apt.16726 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Blesl et al and Srinivasan & van Langenberg papers. To view these articles, visit https://doi.org/10.1111/apt.16478 and https://doi.org/10.1111/apt.16506 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Blesl et al papers. To view these articles, visit https://doi.org/10.1111/apt.16478 and https://doi.org/10.1111/apt.16535 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Nelson et al and Vasant papers. To view these articles, visit https://doi.org/10.1111/apt.16437 and https://doi.org/10.1111/apt.16440 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Nelson et al papers. To view these articles, visit https://doi.org/10.1111/apt.16437 and https://doi.org/10.1111/apt.16443 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Kuo et al and Wuestenberghs & Gourcerol papers. To view these articles, visit https://doi.org/10.1111/apt.16344 and https://doi.org/10.1111/apt.16375 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Kuo et al papers. To view these articles, visit https://doi.org/10.1111/apt.16344 and https://doi.org/10.1111/apt.16395 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Tournier et al and Turbayne and Ward papers. To view these articles, visit https://doi.org/10.1111/apt.16333 and https://doi.org/10.1111/apt.16359 [ABSTRACT FROM AUTHOR]

LINKED CONTENT: This article is linked to Tournier et al and Roblin et al papers. To view these articles, visit https://doi.org/10.1111/apt.16333 and https://doi.org/10.1111/apt.16399 [ABSTRACT FROM AUTHOR]