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Your search keyword '"Paola Maccioni"' showing total 4 results
Start Over Author "Paola Maccioni" Journal alcohol and alcoholism
4 results on '"Paola Maccioni"'

1. SY17AN INTERNATIONAL AND INTERDISCIPLINARY APPROACH TO CHARACTERIZE NEW MODELS OF ALCOHOL ADDICTION IN RODENTS AND NOVEL THERAPIES FOR AUDSY17-1BINGE-LIKE DRINKING IN SARDINIAN ALCOHOL-PREFERRING RATS

Author

C. Acciaro, Paola Maccioni, Irene Lorrai, Carla Lobina, Giancarlo Colombo, Mauro A.M. Carai, G.L. Gessa, Andrea Contini, B. Loi, and A. Zaru

Subjects
medicine.medical_specialty, Ethanol, Alcohol addiction, business.industry, Alcohol dependence, Alcohol, General Medicine, Pharmacology, Alcohol preferring, chemistry.chemical_compound, Animal model, chemistry, medicine, Psychiatry, business
Abstract

This lab has recently proposed a new animal model of binge-like drinking: selectively bred, Sardinian alcohol-preferring (sP) rats with a “history” of repeated exposures to homecage, daily drinking sessions of one hour, with concurrent availability of water and three alcohol concentrations (10%, 20%, and 30%, v/v) and unpredictability of time …

Published
2015
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2. P-65INCREASED REINFORCING AND MOTIVATIONAL PROPERTIES OF ALCOHOL IN SARDINIAN ALCOHOL-PREFERRING RATS AT THE END OF THE DARK PHASE

Author

G.L. Gessa, Giancarlo Colombo, Paola Maccioni, Irene Lorrai, and Andrea Contini

Subjects
medicine.medical_specialty, Ethanol, Alcohol, General Medicine, Drinking session, Alcohol preferring, chemistry.chemical_compound, chemistry, Time schedule, medicine, Psychiatry, Dark phase, Psychology, Social psychology
Abstract

When exposed to daily drinking sessions of one hour, with concurrent availability of multiple alcohol concentrations, and unpredictability of time of alcohol access, Sardinian alcohol-preferring (sP) rats displayed high sensitivity to time schedule, consuming intoxicating amounts of alcohol when the drinking session occurred during the latter part of the dark …

Published
2015
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3. P-48THE GLUCAGON-LIKE PEPTIDE 1 ANALOGUE LIRAGLUTIDE ATTENUATES ALCOHOL-INDUCED REWARD, DECREASES ALCOHOL INTAKE AND PREVENTS RELAPSE-LIKE DRINKING TO ALCOHOL IN OUTBRED RODENTS AS WELL AS REDUCES OPERANT ALCOHOL SELF-ADMINISTRATION IN SARDINIAN ALCOHOL-PREFERRING RATS

Author

Daniel Vallöf, E. Jerlhag, Giancarlo Colombo, Julia Winsa Jörnulf, Paola Maccioni, Emil Egecioglu, M. Mandrapa, and Jörgen A. Engel

Subjects
endocrine system, medicine.medical_specialty, Ethanol, Gastric emptying, Liraglutide, business.industry, digestive, oral, and skin physiology, Alcohol, Stimulation, General Medicine, Glucagon, Glucagon-like peptide-1, chemistry.chemical_compound, Endocrinology, chemistry, Internal medicine, medicine, Self-administration, business, hormones, hormone substitutes, and hormone antagonists, medicine.drug
Abstract

The incretin hormone, glucagon-like peptide 1 (GLP-1), regulates gastric emptying, glucose-dependent stimulation of insulin secretion and glucagon release. GLP-1 analogs are therefore approved for treatment of diabetes type II. GLP-1 receptors are expressed in reward-related areas such …

Published
2015
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4. O1 * FREE ORAL COMMUNICATIONS 1: BASIC NEUROBIOLOGICAL MECHANISMS OF ALCOHOL ADDICTION

Author

Andrzej Z. Pietrzykowski, Mauro A.M. Carai, Yongping Wang, Austin P. Thekkumthala, A. Hot, K. Nixon, M. Collins, E. Neafsey, Carla Lobina, Edward A. Mead, G. Colombo, L. Tejeda, A. Zaru, A. Klintsova, Paola Maccioni, K.-H. Moon, N. Tajuddin, B. Loi, C. Acciaro, and G.L. Gessa

Subjects
medicine.medical_specialty, Ethanol, Dentate gyrus, Neurotoxicity, Hippocampus, Binge drinking, Alcohol, General Medicine, medicine.disease, Neuroprotection, chemistry.chemical_compound, Endocrinology, Alcohol intoxication, chemistry, Internal medicine, medicine, Psychology, Neuroscience
Abstract

O1.1 DYNAMIC REGULATION OF MIR-9 PATHWAYS BY ALCOHOL {#article-title-2} microRNAs are master regulators of gene expression. They are particularly important in brain function. Previously, we observed that short exposure to 20mM ethanol upregulated miR-9 in primary rodent neuronal cultures or brain organotypic slices. These observations prompted us to perform more detailed temporal characteristics and dose-dependence of miR-9 response to ethanol using a regimen of ethanol exposures and withdrawals. We used two physiologically-relevent ethanol concentrations 20 mM and 50 mM. Exposure and/or withdrawal ranged from 15 minutes to 24 hours. We used postnatal day 5 striatal medium spiny neurons harvested from C57BL/6 mice. Total RNA and small RNA fraction (

Published
2013
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