1. Clinical and radiologic findings in progressive facial hemiatrophy (Parry-Romberg syndrome).
- Author
-
Cory RC, Clayman DA, Faillace WJ, McKee SW, and Gama CH
- Subjects
- Arachnoid pathology, Autonomic Nervous System Diseases complications, Brain Diseases diagnosis, Calcinosis diagnosis, Cerebral Angiography, Cerebral Infarction diagnosis, Child, Preschool, Corpus Callosum pathology, Disease Progression, Facial Hemiatrophy diagnosis, Female, Follow-Up Studies, Humans, Magnetic Resonance Imaging, Minerals, Pia Mater pathology, Sympathetic Nervous System pathology, Tomography, X-Ray Computed, Vasomotor System pathology, Brain Diseases pathology, Diagnostic Imaging, Facial Hemiatrophy pathology
- Abstract
We describe the clinical and radiologic changes related to progressive facial hemiatrophy (Parry-Romberg syndrome) occurring during a 20-month period in a child who presented with unilateral neurologic deficits and facial hemiatrophy. CT and MR findings included unilateral focal infarctions in the corpus callosum, diffuse deep and subcortical white matter signal changes, mild cortical thickening, and leptomeningeal enhancement with dense mineral deposition. Angiographic findings were normal. We hypothesize that a noninfectious, unilateral inflammatory process, possibly associated with a chronic vasomotor disturbance and sympathetic nerve chain inflammation, was a major factor in the pathogenesis of this syndrome.
- Published
- 1997