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Medicinal plants are widely used in herbal medicine because they contain a group of chemical compounds that can control the performance of important biological functions in the body of the organism, and in defense against external factors attacking by predators such as insects, parasites, fungi, as well as herbivorous mammals. The vast majority of these chemicals that are possessed by medicinal plants have beneficial effects on the long-term health of the organism, as they have been used effectively to treat many disease conditions that humans suffer from. This study aimed to test the efficacy of certain plant extracts, which are ginger extract, olive pomace and aqueous extract of pomegranate, on Cryptosporidium parivum in the body of an organism. 50 mice (9-10 weeks) and weighing (25-30 g) were used. Infection, the first group was treated with a dose of 657.14 mg / 1.0 mL of ginger water extract, second group 1000 mg / 1.0 mL / g of olive pomace extract in addition to a control group 2 x 10 sachets / 2.0 ml of suspension sachet and 1.0 ml of saline solution Normal, the results showed that all plant extracts achieved 100% positive results in treating mice infected with the parasite. [ABSTRACT FROM AUTHOR]