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Your search keyword '"Miriam Chernoff"' showing total 2 results
Start Over Author "Miriam Chernoff" Journal aids and behavior
2 results on '"Miriam Chernoff"'

1. The Role of Pharmacy Refill Measures in Assessing Adherence and Predicting HIV Disease Markers in Youth with Perinatally-Acquired HIV (PHIV)

Author

Cenk, Yildirim, Patricia A, Garvie, Miriam, Chernoff, Megan L, Wilkins, E Doyle, Patton, Paige L, Williams, Sharon L, Nichols, and Elizabeth, Willen

Subjects
Adult, Male, medicine.medical_specialty, Adolescent, Social Psychology, Disease Response, Anti-HIV Agents, Human immunodeficiency virus (HIV), HIV Infections, medicine.disease_cause, Logistic regression, Article, Medication Adherence, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Antiretroviral Therapy, Highly Active, Internal medicine, medicine, Humans, 030212 general & internal medicine, Pharmacy refill, Pharmacies, 030505 public health, Recall, business.industry, Public health, Public Health, Environmental and Occupational Health, Patient Acceptance of Health Care, Viral Load, Infectious Disease Transmission, Vertical, Health psychology, Outcome and Process Assessment, Health Care, Infectious Diseases, Pharmaceutical Services, HIV-1, Female, Self Report, 0305 other medical science, business, Viral load
Abstract

Antiretroviral (ARV) adherence is critical in monitoring disease response in youth with perinatally-acquired HIV (PHIV). We used pharmacy refill (PR) information for PHIV youth from the PHACS Memory Sub-study to calculate medication availability over 2, 4, and 6 months. PR, a proxy of adherence, was compared with self-reported 7-day adherence in predicting suppressed viral load (SVL

Published
2019
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2. Substance use and its association with psychiatric symptoms in perinatally HIV-infected and HIV-affected adolescents

Author

Kenneth D. Gadow, Edward Morse, Vinnie Di Poalo, Miriam Chernoff, Paige L. Williams, Erin Leister, and Sharon Nachman

Subjects
Male, medicine.medical_specialty, Social Psychology, Adolescent, Substance-Related Disorders, Sexual Behavior, HIV Infections, Logistic regression, Severity of Illness Index, Article, Cohort Studies, Risk-Taking, Risk Factors, HIV Seronegativity, Severity of illness, HIV Seropositivity, medicine, Prevalence, Humans, Psychiatry, Child, Depression (differential diagnoses), Psychiatric Status Rating Scales, Mental Disorders, Public Health, Environmental and Occupational Health, Odds ratio, medicine.disease, Infectious Disease Transmission, Vertical, Infectious Diseases, Logistic Models, Conduct disorder, Major depressive disorder, Female, Psychology, Cohort study
Abstract

Drug use in combination with psychiatric illness may lead to unsafe sexual risk behavior and increased risk for secondary HIV transmission among adolescents with HIV infection. We compared the prevalence of substance use for perinatally HIV-infected youth to uninfected adolescents living in families affected by HIV infection, and evaluated the association of psychiatric symptoms with risk of substance use. Among 299 adolescents (196 HIV+, 103 HIV-) aged 12-18 years enrolled in IMPAACT P1055, a multisite US cohort study, 14% reported substance use at enrollment (HIV+: 13%, HIV-: 16%). In adjusted logistic regression models, adolescents had significantly higher odds of substance use if they met symptom criteria for ADHD [adjusted odds ratio (aOR) = 2.7, Wald χ(2) = 5.18, P = 0.02], major depression or dysthymia (aOR = 4.0, Wald χ(2) = 7.36, P = 0.01), oppositional defiant disorder (aOR = 4.8, Wald χ(2) = 12.7, P = 0.001), or conduct disorder (aOR = 15.4, Wald χ(2) = 28.12, P = 0.001). Among HIV-infected youth, those with lower CD4 lymphocyte percentage (CD4% 25%) had significantly increased risk of substance use (aOR = 2.7, Wald χ(2) = 4.79, P = 0.03). However, there was no overall association of substance use with HIV infection status, and the association between psychiatric symptoms and substance use did not differ by HIV status. Programs to prevent substance use should target both HIV-infected and uninfected adolescents living in families affected by HIV infection, particularly those with psychiatric symptoms.

Published
2010

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