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Start Over Author "Swithin Song" Journal aids (london, england)
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1. Thymic tissue is not evident on high-resolution computed tomography and [¹⁸F]fluoro-deoxy-glucose positron emission tomography scans of aviraemic HIV patients with poor recovery of CD4⁺ T cells

Author

Sara, Tanaskovic, Sonia, Fernandez, Martyn A, French, Roger I, Price, Swithin, Song, Peter D, Robins, and Patricia, Price

Subjects
Adult, Male, Humans, HIV Infections, Thymus Gland, Viral Load, CD4 Lymphocyte Count, Tomography, Emission-Computed
Abstract

Some previously immunodeficient HIV patients responding to antiretroviral therapy display poor recovery of CD4⁺ T cells. Evaluation of the contribution of thymic function requires sensitive detection and quantitation of metabolically active thymic tissue. We describe patients with low but detectable thymopoiesis assessed as circulating CD4⁺ naive T cells expressing CD31. High-resolution computed tomography and PET scans found no residual thymic tissue even though metabolic activity was demonstrable by PET in lymph nodes.

Published
2011

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