1. HIV Pre-exposure Prophylaxis and Buprenorphine at a Drug Detoxification Center During the Opioid Epidemic: Opportunities and Challenges.
- Author
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Assoumou, Sabrina A., Paniagua, Samantha M., Gonzalez, Priscilla, Wang, Jianing, Beckwith, Curt G., White, Laura F., Taylor, Jessica L., Coogan, Kristen, Samet, Jeffrey H., and Linas, Benjamin P.
- Subjects
HIV infections ,RISK-taking behavior ,SUBSTANCE abuse ,CONFIDENCE intervals ,BUPRENORPHINE ,SUBSTANCE abuse treatment ,SURVEYS ,HEALTH literacy ,EPIDEMICS ,RESEARCH funding ,PREVENTIVE medicine ,ODDS ratio ,OPIOID abuse - Abstract
Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) and buprenorphine decrease HIV acquisition. Between November, 2016 and July, 2017, we surveyed persons (N = 200) at a drug detoxification center to assess their interest in PrEP and in buprenorphine, and to examine factors associated with such interests. Over the previous 6 months, 58% (117/200) injected drugs, 87% (173/200) used opioids, 50% (85/171) had condomless sex. Only 22% (26/117) of persons who injected drugs were aware of PrEP, yet 74% (86/116) and 72% (84/116) were interested in oral or injectable PrEP, respectively. Thirty-eight percent (47/125) of persons not receiving buprenorphine or methadone expressed interest in buprenorphine. After multivariable adjustment, Latinx ethnicity was associated with interest in PrEP (aOR 3.80; 95% CI 1.37–10.53), while male gender (aOR 2.76; 95% CI 1.21–6.34) was associated with interest in buprenorphine. Opportunities exist to implement PrEP and buprenorphine within drug detoxification centers. Clinical trial registration NCT02869776. Clinicaltrials.govhttps://clinicaltrials.gov/ct2/show/NCT02869776?term=Sabrina+Assoumou&cond=HIV+HCV&rank=1. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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