Jerusalem artichoke (Helianthus tuberosusL.) can be a weed in pastures and crops or used as silage, but little is known about its N and mineral content and their contribution to forage quality. This study evaluated 19 wild and cultivated genotypes of perennial Jerusalem artichoke for protein and mineral concentrations at various stages of maturity, and compared these to an annual cultivated sunflower (H. annuusL.), ‘Hybrid 894’. The field experiment was conducted on Pullman clay loam (fine, mixed, thermic Torrertic Paleustoll) at Bushland, TX. The 19 perennial genotypes and the commercial sunflower, Hybrid 894, were planted in pure stands. Leaves, stems, and whole plants were evaluated at vegetative, flowering, and fruiting stages to ascertain their nutritive value for ruminants. Crude protein (CP) concentrations of 140 g kg−1and above occurred in leaves of 11 of 19 genotypes at the vegetative stage. Fifteen of the 19 genotypes had whole plant CP of 60 to 90 g kg−1at all stages of maturity. Nutritionally adequate amounts of Ca (2− 8.6 g kg−1) were present in leaves, stems, and whole plants of all genotypes at all stages of maturity. Nutritionally adequate amounts of Mg (1 g kg−1) and K (6.5 g kg−1) were present in leaves and whole plants of most genotypes at all stages of maturity. Leaves, stems, and whole plants of most genotypes had suboptimal P (<2 g kg−1) levels for ruminants at all stages of maturity. Nutritionally adequate amounts of CP, Ca, Mg, and P were present in whole seeds of most genotypes. At varying maturity stages, nutrient levels of some artichoke genotypes are comparable to that of cultivated sunflower. Whether Jerusalem artichoke is mixed with other forbs or grasses in a pasture or hay, or whether it is used as silage, it appears to have the potential to provide a satisfactory nutrition level for ruminants.