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Climate factors strongly impact the growth of grapes and their flavonoid composition, especially due to heat and drought stress. Four varieties—Gelu, Moldova, Purpuriu, and Coarna Neagra—from a Copou vineyard were analyzed to assess the impact of climate change on the anthocyanin concentration in grapes and total chlorophyll content of the leaves, and find possible correlations between these parameters during the two studied years, such as to raise producer awareness regarding the climate impact on table grape vine growth. Moldova and Purpuriu show adaptation to a slight temperature increase above the normal average and also to a water deficit, with increased concentrations of anthocyanins of up to three times. The Moldova variety accumulated low amounts of chlorophyll pigments in most analyzed development phases, indicating a negative correlation between these pigments. Coarna neagra exhibited an increase of the foliar pigments, a variety that proved to be less valuable from the point of view of anthocyanin content. Positive correlations were found between the anthocyanin and chlorophyll concentrations in the case of Gelu, Moldova, and Coarna neagra cultivars during the latter phase of the fruit development, whereas the water deficit in the second year induced negative correlations during fruit development and at the time of harvest for all studied varieties except Moldova. [ABSTRACT FROM AUTHOR]