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One of the most significant challenges that global decision-makers are concerned about is soil contamination. It is also related to food security and soil fertility. The quality of the soil and crops in Egypt are being severely impacted by the increased heavy metal content of the soils in the middle Nile Delta. In Egypt's middle Nile Delta, fifty random soil samples were chosen. Inverse distance weighting (IDW) was used to create the spatial pattern maps for four heavy metals: Cd, Mn, Pb, and Zn. The soil contamination levels in the research area were assessed using principal component analysis (PCA), contamination factors (CF), the geoaccumulation index (I-Geo), and the improved Nemerow pollution index (In). The findings demonstrated that using PCA, the soil heavy metal concentrations were divided into two clusters. Moreover, the majority of the study region (44.47%) was assessed to be heavily to extremely polluted by heavy metals. In conclusion, integrating the contamination indices CF, I-Geo, and In with the GIS technique and multivariate model, analysis establishes a practical and helpful strategy for assessing the hazard of heavy metal contamination. The findings could serve as a basis for decision-makers to create effective heavy metal mitigation efforts. [ABSTRACT FROM AUTHOR]