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Background: The timed up and go (TUG) test assesses balance and mobility performance. Aim: This study aims to investigate the association between TUG time and mortality in Japanese older persons and to clarify possible moderation effects on mortality and TUG time. Methods: In all, 874 participants who were ≥ 65 years of age completed the TUG test and had their anthropometric parameters and physical functions measured. We investigated the association between all-cause mortality and TUG using a Cox regression model that included confounders, and explored the time associated with mortality using a restricted cubic spline. We also performed subgroup analyses to explore whether age, sex, and body mass index (BMI) affected the relationship between TUG time and mortality. Results: The median age and mean follow-up period were 74 and 8.5 years, respectively. Median TUG time was 7.4 s and the prevalence of mortality was 25.7%. TUG time in one second was positively associated with an increased risk of total mortality [hazard ratio (HR): 1.054 (1.016–1.093); P = 0.005] in the Cox regression model. The positive association of mortality and TUG time was present when the TUG was over 10.5 s in the restricted cubic spline curve. Older age (75 years or older) moderated the relationship between TUG time and mortality [Pinteraction = 0.096]. Conclusion: This study demonstrates that TUG time is associated with all-cause mortality in Japanese older adults. [ABSTRACT FROM AUTHOR]

Background and aim: Disability is an important health problem among older individuals, prompting the need for long-term care. Age-related disability is usually associated with mobility; however, little is known about the association between mobility and long-term care. Therefore, this study aimed to clarify the association between the timed up and go (TUG) test measuring mobility and long-term care eligibility. Patients and methods: We analyzed follow-up data of 489 community-dwelling healthy older adults (≥ 65 years) who participated in a prospective observational study. They were divided into certified (59 participants) and uncertified (430 participants) groups based on long-term care eligibility. Anthropometric and physical functioning measures included the TUG test and hand grip strength (HGS), among others. These measures were compared between groups and a multivariate logistic regression analysis evaluated the association between the TUG test times and long-term care eligibility. Results: Participants' minimum follow-up period was 4 years. TUG times were significantly slower (median time: 7.4 vs. 8.3 s, p < 0.001) and HGS and knee-extension strength significantly lower in the certified group than in the uncertified group. The logistic regression analysis showed that TUG times were significantly associated with long-term care eligibility after adjusting for potential covariates. In addition, mediation analysis showed that 53.1% of the association between HGS and long-term care eligibility was mediated through TUG times. Conclusion: The TUG test was associated with long-term care eligibility among healthy older adults, implying that the test may be helpful as a predictor for the early determination of dependence in old age. [ABSTRACT FROM AUTHOR]

Background: While it is accepted that resistance training can improve functional capacity in older individuals, the neuromuscular source of this improvement has yet to be identified.Aim: This study investigated the link between improved neuromuscular performance and functional capacity after a 12-week resistance training period in untrained healthy older individuals.Methods: Fifteen older men and women (60-71 years) adhered to a 4-week control period, followed by 12 weeks of non-linear resistance training for the lower limbs. Maximum dynamic leg press strength (1-RM), maximum isometric knee extension torque and rate of torque development (RTD) were evaluated at − 4, 0, 4, 8, and 12 weeks, and muscle activity was assessed at 0, 4, 8, and 12 weeks. Functional capacity tests (chair rise, stair ascent and descent, and timed up and go) were performed at − 4, 0, and 12 weeks.Results: No changes occurred during the control period, but the group increased their 1-RM strength (from 142 ± 53 to 198 ± 43 kg, p = 0.001), which was accompanied by an increase in vastus lateralis activation (p = 0.008) during the intervention. Increase was observed at all RTD time intervals at week 8 (p < 0.05). Significant improvements in all the functional capacity tests were observed at week 12 (p < 0.05).Discussion: Despite the expected increase in strength, RTD, muscle activity, and functional capacity, there was no significant relationship between the changes in neuromuscular performance and functional capacity. While resistance training elicits various positive improvements in healthy older individuals, actual strength gain did not influence the gain in functional capacity.Conclusion: The present study highlights the exact cause that improved the functional capabilities during resistance training are currently unknown. [ABSTRACT FROM AUTHOR]

Background and aims: The purpose was to explore the impact of balance and mobility training (BMT), balance and mobility plus cognitive training (BMT + C) and no training on the timed up and go (TUG), TUG cognitive (TUGcog), and TUG manual (TUGman) in older adults. A preliminary experiment examined the stability of these TUG measures over a 5-week period in older adults. Methods: Fifteen participants in the BMT group (70.2 ± 3.2 years) and 14 participants in the BMT + C group (68.7 ± 5.5 years) trained one-on-one, 3×/week for 12 weeks on a balance obstacle course. The BMT group and the BMT + C group completed two or three tasks simultaneously, respectively. Fifteen participants in the control group received no training (66.7 ± 4.2 years). The TUG, TUGcog, and TUGman were measured in seconds at baseline, after the 12-week training, and after the 12-week follow-up. During the preliminary experiment, ten participants (67.0 ± 6.9 years) completed the three TUG measures 1/week for 5 weeks. Results: Both the BMT and BMT + C groups, but not the control group, exhibited significantly faster TUG, TUGcog, and TUGman after the intervention and maintained these improvements at the 12-week follow-up. No differences between the BMT and BMT + C groups emerged. The preliminary experiment showed that the three TUG measures were stable across five testing sessions. Discussion and conclusion: Both training groups improved functional mobility after the interventions and sustained these improvements over 12 weeks. This is likely not a function of repeating the TUG, TUGcog, and TUGman tests since no repeated exposure effect was shown. [ABSTRACT FROM AUTHOR]

Objective: The aim of the study is to assess whether obesity affects balance in elderly patients with postural instability. Study design: It is a case-control study, with cases defined by BMI ≥30 kg/m, and developed in a third level university hospital. Methods: We included 135 patients aged 65 years old or more who presented postural instability. Balance assessment was through the sensory organisation test (SOT), limits of stability (LOS) and rhythmic weight shift (RWS) of computerised dynamic posturography (CDP) and the modified timed up-and-go (TUG) test. The patients also completed the Dizziness Handicap Inventory and short Falls Efficacy Scale-International questionnaire. Results: Patients with obesity took longer to perform the modified TUG and required more steps. Also these patients had poorer scores in the subjective tests. In the CDP there were no significant differences in the SOT nor the LOS, and only there was a statistical significant difference in the anterior-posterior directional control of the RWS. Obese patients have a higher risk of fallings compared to non-obese patients. Conclusion: In essence, our results indicate that obesity interferes in the balance of elderly patients with postural instability, putting them at a greater risk of fallings, performing worse dynamic tasks and feeling more disabled. Although continued education on training balance may be useful in older population, since the obese group shows more rate of fallers, rehabilitation programmes focus on dynamic tasks in these patients could be useful to reduce their fall risk and improve their quality of life. [ABSTRACT FROM AUTHOR]