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12 results on '"Vijg, Jan"'

1. Meeting Report: Aging Research and Drug Discovery

Author

Meron, Esther, Thaysen, Maria, Angeli, Suzanne, Antebi, Adam, Barzilai, Nir, Baur, Joseph A, Bekker-Jensen, Simon, Birkisdottir, Maria, Bischof, Evelyne, Bruening, Jens, Brunet, Anne, Buchwalter, Abigail, Cabreiro, Filipe, Cai, Shiqing, Chen, Brian H, Ermolaeva, Maria, Ewald, Collin Y, Ferrucci, Luigi, Florian, Maria Carolina, Fortney, Kristen, Freund, Adam, Georgievskaya, Anastasia, Gladyshev, Vadim N, Glass, David, Golato, Tyler, Gorbunova, Vera, Hoejimakers, Jan, Houtkooper, Riekelt H, Jager, Sibylle, Jaksch, Frank, Janssens, Georges, Jensen, Martin Borch, Kaeberlein, Matt, Karsenty, Gerard, de Keizer, Peter, Kennedy, Brian, Kirkland, James L, Kjaer, Michael, Kroemer, Guido, Lee, Kai-Fu, Lemaitre, Jean-Marc, Liaskos, David, Longo, Valter D, Lu, Yu-Xuan, MacArthur, Michael R, Maier, Andrea B, Manakanatas, Christina, Mitchell, Sarah J, Moskalev, Alexey, Niedernhofer, Laura, Ozerov, Ivan, Partridge, Linda, Passegué, Emmanuelle, Petr, Michael A, Peyer, James, Radenkovic, Dina, Rando, Thomas A, Rattan, Suresh, Riedel, Christian G, Rudolph, Lenhard, Ai, Ruixue, Serrano, Manuel, Schumacher, Björn, Sinclair, David A, Smith, Ryan, Suh, Yousin, Taub, Pam, Trapp, Alexandre, Trendelenburg, Anne-Ulrike, Valenzano, Dario Riccardo, Verburgh, Kris, Verdin, Eric, Vijg, Jan, Westendorp, Rudi GJ, Zonari, Alessandra, Bakula, Daniela, Zhavoronkov, Alex, and Scheibye-Knudsen, Morten

Subjects
Aging, aging, drug discovery, conference, AI, longevity, Biochemistry and Cell Biology, Physiology, Oncology and Carcinogenesis, Developmental Biology
Abstract

Aging is the single largest risk factor for most chronic diseases, and thus possesses large socioeconomic interest to continuously aging societies. Consequently, the field of aging research is expanding alongside a growing focus from the industry and investors in aging research. This year's 8th Annual Aging Research and Drug Discovery (ARDD) meeting was organized as a hybrid meeting from August 30th to September 3rd 2021 with more than 130 attendees participating on-site at the Ceremonial Hall at University of Copenhagen, Denmark, and 1800 engaging online. The conference comprised of presentations from 75 speakers focusing on new research in topics including mechanisms of aging and how these can be modulated as well as the use of AI and new standards of practices within aging research. This year, a longevity workshop was included to build stronger connections with the clinical community.

Published
2022

2. ARDD 2020: from aging mechanisms to interventions

Author

Mkrtchyan, Garik V, Abdelmohsen, Kotb, Andreux, Pénélope, Bagdonaite, Ieva, Barzilai, Nir, Brunak, Søren, Cabreiro, Filipe, de Cabo, Rafael, Campisi, Judith, Cuervo, Ana Maria, Demaria, Marco, Ewald, Collin Y, Fang, Evandro Fei, Faragher, Richard, Ferrucci, Luigi, Freund, Adam, Silva-García, Carlos G, Georgievskaya, Anastasia, Gladyshev, Vadim N, Glass, David J, Gorbunova, Vera, de Grey, Aubrey, He, Wei-Wu, Hoeijmakers, Jan, Hoffmann, Eva, Horvath, Steve, Houtkooper, Riekelt H, Jensen, Majken K, Jensen, Martin Borch, Kane, Alice, Kassem, Moustapha, de Keizer, Peter, Kennedy, Brian, Karsenty, Gerard, Lamming, Dudley W, Lee, Kai-Fu, MacAulay, Nanna, Mamoshina, Polina, Mellon, Jim, Molenaars, Marte, Moskalev, Alexey, Mund, Andreas, Niedernhofer, Laura, Osborne, Brenna, Pak, Heidi H, Parkhitko, Andrey, Raimundo, Nuno, Rando, Thomas A, Rasmussen, Lene Juel, Reis, Carolina, Riedel, Christian G, Franco-Romero, Anais, Schumacher, Björn, Sinclair, David A, Suh, Yousin, Taub, Pam R, Toiber, Debra, Treebak, Jonas T, Valenzano, Dario Riccardo, Verdin, Eric, Vijg, Jan, Young, Sergey, Zhang, Lei, Bakula, Daniela, Zhavoronkov, Alex, and Scheibye-Knudsen, Morten

Subjects
Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Clinical Sciences, Biological Sciences, Aging, Good Health and Well Being, Artificial Intelligence, Biomedical Research, Cellular Senescence, Congresses as Topic, Drug Discovery, Humans, Life Style, Longevity, Pharmaceutical Preparations, aging, interventions, drug discovery, artificial intelligence, Biochemistry and cell biology, Clinical sciences
Abstract

Aging is emerging as a druggable target with growing interest from academia, industry and investors. New technologies such as artificial intelligence and advanced screening techniques, as well as a strong influence from the industry sector may lead to novel discoveries to treat age-related diseases. The present review summarizes presentations from the 7th Annual Aging Research and Drug Discovery (ARDD) meeting, held online on the 1st to 4th of September 2020. The meeting covered topics related to new methodologies to study aging, knowledge about basic mechanisms of longevity, latest interventional strategies to target the aging process as well as discussions about the impact of aging research on society and economy. More than 2000 participants and 65 speakers joined the meeting and we already look forward to an even larger meeting next year. Please mark your calendars for the 8th ARDD meeting that is scheduled for the 31st of August to 3rd of September, 2021, at Columbia University, USA.

Published
2020

3. Impact papers on aging in 2009

Author

Blagosklonny, Mikhail V, Campisi, Judy, Sinclair, David A, Bartke, Andrzej, Blasco, Maria A, Bonner, William M, Bohr, Vilhelm A, Jr, Robert M Brosh, Brunet, Anne, DePinho, Ronald A, Donehower, Lawrence A, Finch, Caleb E, Finkel, Toren, Gorospe, Myriam, Gudkov, Andrei V, Hall, Michael N, Hekimi, Siegfried, Helfand, Stephen L, Karlseder, Jan, Kenyon, Cynthia, Kroemer, Guido, Longo, Valter, Nussenzweig, Andre, Osiewacz, Heinz D, Peeper, Daniel S, Rando, Thomas A, Rudolph, K Lenhard, Sassone-Corsi, Paolo, Serrano, Manuel, Sharpless, Norman E, Skulachev, Vladimir P, Tilly, Jonathan L, Tower, John, Verdin, Eric, and Vijg, Jan

Subjects
Biochemistry and Cell Biology, Biological Sciences, Genetics, Aging, 1.1 Normal biological development and functioning, Underpinning research, Good Health and Well Being, Adult Stem Cells, Animals, Autophagy, Caloric Restriction, Cellular Reprogramming, Circadian Rhythm, DNA Damage, Humans, Mitochondria, Neoplasms, Oxidative Stress, RNA Processing, Post-Transcriptional, Telomere, aging, senescence, signal transduction, genes for longevity, Biochemistry and cell biology, Clinical sciences
Abstract

The Editorial Board of Aging reviews research papers published in 2009, which they believe have or will have significant impact on aging research. Among many others, the topics include genes that accelerate aging or in contrast promote longevity in model organisms, DNA damage responses and telomeres, molecular mechanisms of life span extension by calorie restriction and pharmacological interventions into aging. The emerging message in 2009 is that aging is not random but determined by a genetically-regulated longevity network and can be decelerated both genetically and pharmacologically.

Published
2010

4. A review of the biomedical innovations for healthy longevity

Author

Moskalev, Alexey, primary, Anisimov, Vladimir, additional, Aliper, Aleksander, additional, Artemov, Artem, additional, Asadullah, Khusru, additional, Belsky, Daniel, additional, Baranova, Ancha, additional, de Grey, Aubrey, additional, Dixit, Vishwa Deep, additional, Debonneuil, Edouard, additional, Dobrovolskaya, Eugenia, additional, Fedichev, Peter, additional, Fedintsev, Alexander, additional, Fraifeld, Vadim, additional, Franceschi, Claudio, additional, Freer, Rosie, additional, Fülöp, Tamas, additional, Feige, Jerome, additional, Gems, David, additional, Gladyshev, Vadim, additional, Gorbunova, Vera, additional, Irincheeva, Irina, additional, Jager, Sibylle, additional, Jazwinski, S. Michal, additional, Kaeberlein, Matt, additional, Kennedy, Brian, additional, Khaltourina, Daria, additional, Kovalchuk, Igor, additional, Kovalchuk, Olga, additional, Kozin, Sergey, additional, Kulminski, Alexander, additional, Lashmanova, Ekaterina, additional, Lezhnina, Ksenia, additional, Liu, Guang-Hui, additional, Longo, Valter, additional, Mamoshina, Polina, additional, Maslov, Alexander, additional, Pedro de Magalhaes, Joao, additional, Mitchell, James, additional, Mitnitski, Arnold, additional, Nikolsky, Yuri, additional, Ozerov, Ivan, additional, Pasyukova, Elena, additional, Peregudova, Darya, additional, Popov, Vasily, additional, Proshkina, Ekaterina, additional, Putin, Evgeny, additional, Rogaev, Evgeny, additional, Rogina, Blanka, additional, Schastnaya, Jane, additional, Seluanov, Andrey, additional, Shaposhnikov, Mikhail, additional, Simm, Andreas, additional, Skulachev, Vladimir, additional, Skulachev, Maxim, additional, Solovev, Ilya, additional, Spindler, Stephen, additional, Stefanova, Natalia, additional, Suh, Yousin, additional, Swick, Andrew, additional, Tower, John, additional, Gudkov, Andrei V., additional, Vijg, Jan, additional, Voronkov, Andrey, additional, West, Michael, additional, Wagner, Wolfgang, additional, Yashin, Anatoliy, additional, Zemskaya, Nadezhda, additional, Zhumadilov, Zhaxybay, additional, and Zhavoronkov, Alex, additional

Published
2017
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6. Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan

Author

Patrick, Alison, primary, Seluanov, Michael, additional, Hwang, Chaewon, additional, Tam, Jonathan, additional, Khan, Tanya, additional, Morgenstern, Ari, additional, Wiener, Lauren, additional, Vazquez, Juan M., additional, Zafar, Hiba, additional, Wen, Robert, additional, Muratkalyeva, Malika, additional, Doerig, Katherine, additional, Zagorulya, Maria, additional, Cole, Lauren, additional, Catalano, Sophia, additional, Lobo Ladd, Aliny AB, additional, Coppi, A. Augusto, additional, Coşkun, Yüksel, additional, Tian, Xiao, additional, Ablaeva, Julia, additional, Nevo, Eviatar, additional, Gladyshev, Vadim N., additional, Zhang, Zhengdong D., additional, Vijg, Jan, additional, Seluanov, Andrei, additional, and Gorbunova, Vera, additional

Published
2016
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7. DNA repair in species with extreme lifespan differences

Author

MacRae, Sheila L, primary, Croken, Matthew McKnight, additional, Calder, R.B, additional, Aliper, Alexander, additional, Milholland, Brandon, additional, White, Ryan R, additional, Zhavoronkov, Alexander, additional, Gladyshev, Vadim N, additional, Seluanov, Andrei, additional, Gorbunova, Vera, additional, Zhang, Zhengdong D, additional, and Vijg, Jan, additional

Published
2015
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9. Centenarians as super-controls to assess the biological relevance of genetic risk factors for common age-related diseases: A proof of principle on type 2 diabetes

Author

Garagnani, Paolo, primary, Giuliani, Cristina, additional, Pirazzini, Chiara, additional, Olivieri, Fabiola, additional, Bacalini, Maria Giulia, additional, Ostan, Rita, additional, Mari, Daniela, additional, Passarino, Giuseppe, additional, Monti, Daniela, additional, Bonfigli, Anna Rita, additional, Boemi, Massimo, additional, Ceriello, Antonio, additional, Genovese, Stefano, additional, Sevini, Federica, additional, Luiselli, Donata, additional, Tieri, Paolo, additional, Capri, Miriam, additional, Salvioli, Stefano, additional, Vijg, Jan, additional, Suh, Yousin, additional, Delledonne, Massimo, additional, Testa, Roberto, additional, and Franceschi, Claudio, additional

Published
2013
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10. The second international conference "genetics of aging and longevity"

Author

Anisimov, Vladimir N., primary, Bartke, Andrzej, additional, Barzilai, Nir, additional, Batin, Mikhail A., additional, Blagosklonny, Mikhail V., additional, Brown‐Borg, Holly, additional, Budovskaya, Yelena, additional, Campisi, Judith, additional, Friguet, Bertrand, additional, Fraifeld, Vadim, additional, Franceschi, Claudio, additional, Gems, David, additional, Gladyshev, Vadim, additional, Gorbunova, Vera, additional, Gudkov, Andrei V., additional, Kennedy, Brian, additional, Konovalenko, Maria, additional, Kraemer, Brian, additional, Moskalev, Alexey, additional, Petropoulos, Isabelle, additional, Pasyukova, Elena, additional, Rattan, Suresh, additional, Rogina, Blanka, additional, Seluanov, Andrei, additional, Shaposhnikov, Mikhail, additional, Reis, Robert Shmookler, additional, Tavernarakis, Nektarios, additional, Vijg, Jan, additional, Yashin, Anatoli, additional, and Zimniak, Piotr, additional

Published
2012
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12. Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity.

Author

Lyu YX, Fu Q, Wilczok D, Ying K, King A, Antebi A, Vojta A, Stolzing A, Moskalev A, Georgievskaya A, Maier AB, Olsen A, Groth A, Simon AK, Brunet A, Jamil A, Kulaga A, Bhatti A, Yaden B, Pedersen BK, Schumacher B, Djordjevic B, Kennedy B, Chen C, Huang CY, Correll CU, Murphy CT, Ewald CY, Chen D, Valenzano DR, Sołdacki D, Erritzoe D, Meyer D, Sinclair DA, Chini EN, Teeling EC, Morgen E, Verdin E, Vernet E, Pinilla E, Fang EF, Bischof E, Mercken EM, Finger F, Kuipers F, Pun FW, Gyülveszi G, Civiletto G, Zmudze G, Blander G, Pincus HA, McClure J, Kirkland JL, Peyer J, Justice JN, Vijg J, Gruhn JR, McLaughlin J, Mannick J, Passos J, Baur JA, Betts-LaCroix J, Sedivy JM, Speakman JR, Shlain J, von Maltzahn J, Andreasson KI, Moody K, Palikaras K, Fortney K, Niedernhofer LJ, Rasmussen LJ, Veenhoff LM, Melton L, Ferrucci L, Quarta M, Koval M, Marinova M, Hamalainen M, Unfried M, Ringel MS, Filipovic M, Topors M, Mitin N, Roy N, Pintar N, Barzilai N, Binetti P, Singh P, Kohlhaas P, Robbins PD, Rubin P, Fedichev PO, Kamya P, Muñoz-Canoves P, de Cabo R, Faragher RGA, Konrad R, Ripa R, Mansukhani R, Büttner S, Wickström SA, Brunemeier S, Jakimov S, Luo S, Rosenzweig-Lipson S, Tsai SY, Dimmeler S, Rando TA, Peterson TR, Woods T, Wyss-Coray T, Finkel T, Strauss T, Gladyshev VN, Longo VD, Dwaraka VB, Gorbunova V, Acosta-Rodríguez VA, Sorrentino V, Sebastiano V, Li W, Suh Y, Zhavoronkov A, Scheibye-Knudsen M, and Bakula D

Subjects
Humans, Aging physiology, Geroscience methods, Artificial Intelligence, Biomarkers metabolism, Biotechnology methods, Longevity physiology
Abstract

The recent unprecedented progress in ageing research and drug discovery brings together fundamental research and clinical applications to advance the goal of promoting healthy longevity in the human population. We, from the gathering at the Aging Research and Drug Discovery Meeting in 2023, summarised the latest developments in healthspan biotechnology, with a particular emphasis on artificial intelligence (AI), biomarkers and clocks, geroscience, and clinical trials and interventions for healthy longevity. Moreover, we provide an overview of academic research and the biotech industry focused on targeting ageing as the root of age-related diseases to combat multimorbidity and extend healthspan. We propose that the integration of generative AI, cutting-edge biological technology, and longevity medicine is essential for extending the productive and healthy human lifespan.

Published
2024
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