1. Therapeutic effect of hyperbaric oxygen treatment combined with pharmacotherapy for sudden deafness: A retrospective study
- Author
-
Huai Huang, Jianxin Wen, Shuilin Ye, Jing Gu, and Rong-hao Yu
- Subjects
Pharmacology ,medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Therapeutic effect ,Pharmaceutical Science ,Retrospective cohort study ,Surgery ,Combined treatment ,Hyperbaric oxygen ,Pharmacotherapy ,Time windows ,Anesthesia ,medicine ,Pure tone audiometry ,Symptom onset ,business - Abstract
To compare the therapeutic effect of hyperbaric oxygen (HBO) treatment and pharmacotherapy with that of pharmacotherapy alone in sudden deafness (SD) patients, and to evaluate the impact of therapeutic time window on the therapeutic effect, a total of 264 patients with SD were assigned into HBO group and control group. Patients in the HBO group received routine pharmacotherapy and HBO treatment, and those in the control group were only routinely treated with drugs. Acoustic impedance measurement and pure tone audiometry were performed before and after treatment. The hearing after treatment at different time windows was compared with that before treatment. The overall efficacy in the HBO group was significantly superior to that of the control group (P 0.05). The results demonstrated that the efficacy of HBO combined treatment was superior to that of routine pharmacotherapy for SD patients, and HBO treatment can favorably improve the hearing of these patients. HBO treatment initiated early after symptom onset (
- Published
- 2012