Virginia Fernandes Moça Trevisani, Aysa César Pinheiro, Sonia Cristina de Magalhães Souza Fialho, Marilena Leal Mesquita Silvestre Fernandes, Alisson Pugliesi, Sandra Gofinet Pasoto, Maria Lucia Lemos Lopes, Lissiane Karine Noronha Guedes, Samira Tatiyama Miyamoto, Laura Caldas dos Santos, Simone Appenzeller, Tania Fidelix, Sandra Lúcia Euzébio Ribeiro, Danielle Christinne Soares Egypto de Brito, Tatiana Nayara Libório-Kimura, Maria Carmen Lopes Ferreira Silva Santos, Diego Ustárroz Cantali, Juliana D.’Agostino Gennari, Karina Gatz Capobianco, Vinicius Tassoni Civile, Ana Carolina Pereira Nunes Pinto, Aline Pereira da Rocha, César Ramos Rocha-Filho, Fabiola Reis Oliveira, and Valeria Valim
Sjogren's syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltration of the exocrine glands and other organs, associated with sicca syndrome but also with systemic involvement with varying degrees of severity. Despite their importance, some systemic manifestations, mainly liver, gastrointestinal, and pancreatic are not routinely evaluated. To address these manifestations, the Sjögren's Syndrome Committee of the Brazilian Society of Rheumatology conducted a broad systematic review of the literature on studies investigating prevalence and diagnosis of these symptoms in Sjogren´s patients and made recommendations based on the findings. Agreement between the experts was achieved using the Delphi method. This is the second part of this guideline, providing 6 recommendations for liver, gastrointestinal, and pancreatic care of SS patients.