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Start Over Descriptor "Three components" Journal advanced synthesis & catalysis
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1. Visible‐Light‐Induced Three‐Component Intermolecular Trifluoromethyl‐Alkenylation Reactions of Unactivated Alkenes.

Author

Guo, Yuan‐Qiang, Wang, Kaihua, Wang, Ruiguo, Song, Hongjian, Liu, Yuxiu, and Wang, Qingmin

Subjects
*FUNCTIONAL groups, *ALKENES
Abstract

Herein, we describe a practical protocol for efficient, mild, visible‐light‐induced three‐component intermolecular trifluoromethyl‐alkenylation reactions of unactivated alkenes. The protocol has good functional group tolerance and a broad substrate scope. Using this protocol, we not only introduced a trifluoromethyl group into alkenes but also converted unactivated alkenes to styrene‐based activated alkenes, in addition to accomplishing late‐stage functionalization of pharmaceutical intermediates. [ABSTRACT FROM AUTHOR]

Published
2021
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