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Start Over Author "Shuang Jing" Journal advanced synthesis & catalysis
5 results on '"Shuang Jing"'

5. [4+2]‐Cycloaddition of para‐Quinone Methides with Hexahydro‐1,3,5‐Triazines: Access to 1,3‐Benzoxazine Derivatives.

Author

Cheng, Xiao, Zhou, Shuang‐Jing, Xu, Guo‐Yong, Wang, Long, Yang, Qing‐Qing, and Xuan, Jun

Subjects
*TRIAZINE derivatives, *FUNCTIONAL groups, *HETEROCYCLIC compounds, *RING formation (Chemistry)
Abstract

A [4+2]‐cycloaddition of para‐quinone methides with hexahydro‐1,3,5‐triazines is reported. The reaction occurs under very mild conditions (catalyst‐, ligand‐, and base‐free), exhibits a broad substrate scope and excellent functional group tolerance, and affords a series of biologically important 1,3‐benzoxazine derivatives in good to excellent yields. Moreover, the successful late‐stage functionalization of pharmaceutically relevant compounds further renders the approach valuable. [ABSTRACT FROM AUTHOR]

Published
2020
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