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Your search keyword '"Wang Weiwei"' showing total 11 results
Start Over Author "Wang Weiwei" Journal advanced science
11 results on '"Wang Weiwei"'

2. Biodegradable Cardiac Occluder with Surface Modification by Gelatin–Peptide Conjugate to Promote Endogenous Tissue Regeneration

Author

Kong, Pengxu, primary, Liu, Xiang, additional, Li, Zefu, additional, Wang, Jingrong, additional, Gao, Rui, additional, Feng, Shuyi, additional, Li, Hang, additional, Zhang, Fengwen, additional, Feng, Zujian, additional, Huang, Pingsheng, additional, Wang, Shouzheng, additional, Zhuang, Donglin, additional, Ouyang, Wenbin, additional, Wang, Weiwei, additional, and Pan, Xiangbin, additional

Published
2023
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4. Extracellular Matrix/Glycopeptide Hybrid Hydrogel as an Immunomodulatory Niche for Endogenous Cardiac Repair after Myocardial Infarction

Author

Kong, Pengxu, primary, Dong, Jing, additional, Li, Wenchao, additional, Li, Zefu, additional, Gao, Rui, additional, Liu, Xiang, additional, Wang, Jingrong, additional, Su, Qi, additional, Wen, Bin, additional, Ouyang, Wenbin, additional, Wang, Shouzheng, additional, Zhang, Fengwen, additional, Feng, Shuyi, additional, Zhuang, Donglin, additional, Xie, Yongquan, additional, Zhao, Guangzhi, additional, Yi, Hang, additional, Feng, Zujian, additional, Wang, Weiwei, additional, and Pan, Xiangbin, additional

Published
2023
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5. Supramolecular Polymer‐Nanomedicine Hydrogel Loaded with Tumor Associated Macrophage‐Reprogramming polyTLR7/8a Nanoregulator for Enhanced Anti‐Angiogenesis Therapy of Orthotopic Hepatocellular Carcinoma

Author

Liu, Xiang, primary, Huangfu, Yini, additional, Wang, Jingrong, additional, Kong, Pengxu, additional, Tian, Weijun, additional, Liu, Peng, additional, Fang, Chuang, additional, Li, Shuangyang, additional, Nie, Yu, additional, Feng, Zujian, additional, Huang, Pingsheng, additional, Shi, Shengbin, additional, Zhang, Chuangnian, additional, Dong, Anjie, additional, and Wang, Weiwei, additional

Published
2023
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6. Biodegradable Cardiac Occluder with Surface Modification by Gelatin–Peptide Conjugate to Promote Endogenous Tissue Regeneration.

Author

Kong, Pengxu, Liu, Xiang, Li, Zefu, Wang, Jingrong, Gao, Rui, Feng, Shuyi, Li, Hang, Zhang, Fengwen, Feng, Zujian, Huang, Pingsheng, Wang, Shouzheng, Zhuang, Donglin, Ouyang, Wenbin, Wang, Weiwei, and Pan, Xiangbin

Subjects
GELATIN, ATRIAL septal defects, CARDIAC regeneration, CONGENITAL heart disease, REGENERATION (Biology), HEART abnormalities
Abstract

Transcatheter intervention has been the preferred treatment for congenital structural heart diseases by implanting occluders into the heart defect site through minimally invasive access. Biodegradable polymers provide a promising alternative for cardiovascular implants by conferring therapeutic function and eliminating long‐term complications, but inducing in situ cardiac tissue regeneration remains a substantial clinical challenge. PGAG (polydioxanone/poly (l‐lactic acid)–gelatin–A5G81) occluders are prepared by covalently conjugating biomolecules composed of gelatin and layer adhesive protein‐derived peptides (A5G81) to the surface of polydioxanone and poly (l‐lactic acid) fibers. The polymer microfiber–biomacromolecule–peptide frame with biophysical and biochemical cues could orchestrate the biomaterial–host cell interactions, by recruiting endogenous endothelial cells, promoting their adhesion and proliferation, and polarizing immune cells into anti‐inflammatory phenotypes and augmenting the release of reparative cytokines. In a porcine atrial septal defect (ASD) model, PGAG occluders promote in situ tissue regeneration by accelerating surface endothelialization and regulating immune response, which mitigate inflammation and fibrosis formation, and facilitate the fusion of occluder with surrounding heart tissue. Collectively, this work highlights the modulation of cell–biomaterial interactions for tissue regeneration in cardiac defect models, ensuring endothelialization and extracellular matrix remodeling on polymeric scaffolds. Bioinspired cell–material interface offers a highly efficient and generalized approach for constructing bioactive coatings on medical devices. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Cancer Radiotherapy: Enhanced Radiosensitization by Gold Nanoparticles with Acid‐Triggered Aggregation in Cancer Radiotherapy (Adv. Sci. 8/2019)

Author

Zhang, Yumin, primary, Huang, Fan, additional, Ren, Chunhua, additional, Liu, Jinjian, additional, Yang, Lijun, additional, Chen, Shizhu, additional, Chang, Jinglin, additional, Yang, Cuihong, additional, Wang, Weiwei, additional, Zhang, Chuangnian, additional, Liu, Qiang, additional, Liang, Xing‐Jie, additional, and Liu, Jianfeng, additional

Published
2019
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10. Interventional Photothermal Therapy Enhanced Brachytherapy: A New Strategy to Fight Deep Pancreatic Cancer

Author

Zhang, Fengrong, primary, Han, Xianlin, additional, Hu, Yanyan, additional, Wang, Shunhao, additional, Liu, Shuang, additional, Pan, Xueting, additional, Wang, Hongyu, additional, Ma, Junjie, additional, Wang, Weiwei, additional, Li, Shanshan, additional, Wu, Qingyuan, additional, Shen, Heyun, additional, Yu, Xiaoling, additional, Yuan, Qipeng, additional, and Liu, Huiyu, additional

Published
2019
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11. Enhanced Radiosensitization by Gold Nanoparticles with Acid‐Triggered Aggregation in Cancer Radiotherapy

Author

Zhang, Yumin, primary, Huang, Fan, additional, Ren, Chunhua, additional, Liu, Jinjian, additional, Yang, Lijun, additional, Chen, Shizhu, additional, Chang, Jinglin, additional, Yang, Cuihong, additional, Wang, Weiwei, additional, Zhang, Chuangnian, additional, Liu, Qiang, additional, Liang, Xing‐Jie, additional, and Liu, Jianfeng, additional

Published
2019
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