1. Synthesis and characterization of Zn 2+ and SeO 3 2− co-substituted nano-hydroxyapatite
- Author
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Yamin Chai, Wandong Zhang, Yonglan Wang, and Xianghua Xu
- Subjects
Materials science ,Dopant ,General Chemical Engineering ,Simulated body fluid ,chemistry.chemical_element ,Mineralogy ,Nanoparticle ,02 engineering and technology ,Zinc ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Apatite ,0104 chemical sciences ,chemistry ,Mechanics of Materials ,visual_art ,visual_art.visual_art_medium ,Zeta potential ,Surface charge ,0210 nano-technology ,Selenium ,Nuclear chemistry - Abstract
Synthetic hydroxyapatite (HAP) containing both Zn 2+ and SeO 3 2− was synthesized via a co-precipitation method and the effects of the two ion concentrations on the morphology, surface charge and composition of the HAP were studied. The Zn 2+ and SeO 3 2− co-substituted hydroxyapatite (ZnSeHAP) samples were characterized by various techniques. The synthetic ZnSeHAP products were well-crystallized with typical apatite structures. The zinc and selenium were incorporated into the HAP lattice by respectively replacing some of the Ca 2+ with Zn 2+ and some of the PO 4 3− with SeO 3 2− . As the Zn content increased, the a -axis of the HAP lattice increased and the c -axis decreased. An increase in Zn in the HAP lattice also led to a decrease in the surface charge when ZnSeHAP was suspended in simulated body fluid (pH 7.4). This study shows that the surface properties of hydroxyapatite can be controlled by adding suitable dopants, which is useful for biomedical applications.
- Published
- 2016
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