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1. A Janus Mucoadhesive and Omniphobic Device for Gastrointestinal Retention.

Author

Lee YA, Zhang S, Lin J, Langer R, and Traverso G

Subjects
Animals, Drug Delivery Systems methods, Humans, Swine, Water metabolism, Adhesives metabolism, Gastrointestinal Tract metabolism, Mucous Membrane metabolism
Abstract

A novel Janus device with omniphobic and mucoadhesive sides that exhibit the unique capacity for antifouling and extended gastrointestinal retention is fabricated. This system enables repulsion of the food and fluid stream by the luminal-facing omniphobic side and allows attachment to the gastrointestinal mucosa by the mucoadhesive side., (© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Published
2016
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