1. Development of a Highly Selective, Sensitive, and Fast Response Upconversion Luminescent Platform for Hydrogen Sulfide Detection
- Author
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Wang Xu, Chai Lean Teoh, Young-Tae Chang, Lu Wang, Juanjuan Peng, Xiaogang Liu, Dongdong Su, Animesh Samanta, Lin Yuan, and Xiao Zeng
- Subjects
Materials science ,Hydrogen sulfide ,Nanoparticle ,Nanotechnology ,02 engineering and technology ,equipment and supplies ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Highly selective ,01 natural sciences ,Photon upconversion ,0104 chemical sciences ,Electronic, Optical and Magnetic Materials ,Biomaterials ,Upconversion nanoparticles ,chemistry.chemical_compound ,chemistry ,Electrochemistry ,Monitoring methods ,0210 nano-technology ,Luminescence - Abstract
Hydrogen sulfide (H2S) has been recognized as one of most important gaseous signaling molecules mediated by a variety of physiological and pathological processes. Yet, its functions remain largely elusive due to the lack of potent monitoring methods. Hereby this issue is addressed with a powerful new platform—dye-assembled upconversion nanoparticles (UCNPs). A series of chromophores with different absorption bands and fast responses towards H2S is combined with UCNPs and results in a library of H2S sensors with responsive emission signals ranging from the visible to the near-infrared (NIR) region. These nanoprobes demonstrate highly selective and rapid responses to H2S in vitro and in cells. Furthermore, H2S levels in blood can be detected using the developed nanoprobes. Hence the reported H2S sensing platform can serve as a powerful diagnostic tool to research H2S functions and to investigate H2S-related diseases.
- Published
- 2015