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Noninvasive and real-time cuffless blood pressure (BP) measurement realizes the idea of unobtrusive and continuous BP monitoring which is essential for diagnosis and prevention of cardiovascular diseases associated with hypertension. In this paper, a wearable sensor patch system that integrates flexible piezoresistive sensor (FPS) and epidermal electrocardiogram (ECG) sensors for cuffless BP measurement is presented. By developing parametric models on the FPS sensing mechanism and optimizing operational conditions, a highly stable epidermal pulse monitoring method is established and beat-to-beat BP measurement from the ECG and epidermal pulse signals is demonstrated. In particular, this study highlights the compromise between sensor sensitivity and signal stability. As compared with the current optical-based cuffless BP measurement devices, the sensing patch requires much lower power consumption (3 nW) and is capable of detecting subtle physiological signal variations, e.g., pre and postexercises, thus providing a promising solution for low-power, real-time, and home-based BP monitoring. [ABSTRACT FROM AUTHOR]

N. Zhao and coworkers demonstrate, on page 1178, a low‐power, wearable sensor system that integrates a flexible piezoresistive sensor and epidermal electrocardiogram sensors, for extracting real‐time beat‐to‐beat blood pressure measurements. Through parametric modelling and operation optimization, highly stable epidermal pulse monitoring is achieved, and the compromise between sensor sensitivity and signal stability is highlighted. [ABSTRACT FROM AUTHOR]

Wearable pressure sensors enable long‐term real‐time health monitoring in a noninvasive and power‐efficient way; however, the sensors are often required to be precisely applied at the optimal measurement spot, e.g., nearby radial artery, for signal acquisition, causing inconvenience for untrained users or the elders. In this paper, a wearable liquid‐capsule sensor platform embedded with a piezo‐resistive pressure sensor is presented for continuous, accurate, and alignment‐relaxed physiological monitoring, i.e., heart rate (HR) and blood pressure (BP) tracking. The flexible capsule design ensures comfort and good device conformation to any skin regions. For HR and BP measurements, experiments are performed on 12 human subjects. The results show that the capsuled sensor can continuously track: 1) HR with a mean absolute difference (MAD) of 0.88 beats per minute (bpm) and 2) BP with a MAD<3 mmHg for both diastolic and systolic blood pressure. The new liquid‐capsule‐based sensor platform may help to realize an accurate, flexible, robust, and low‐power solution for next‐generation wearable health monitoring devices. A wearable liquid‐capsule sensor platform embedded with a piezo‐resistive pressure sensor for continuous, accurate, and alignment‐relaxed physiological monitoring, i.e., heart rate and blood pressure tracking, is realized. [ABSTRACT FROM AUTHOR]