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Resumen El papel de la vitamina D en enfermedades cutaneas ha cobrado interes en los ultimos anos. La relacion entre esta vitamina y algunas dermatosis ha supuesto la publicacion de multiples trabajos al respecto. Como dermatologos, conocer sus principales fuentes, sintesis, niveles plasmaticos y algunos de los factores modificadores son varios de los aspectos a recordar. Asimismo, es preciso resaltar los ultimos descubrimientos sobre el papel de la vitamina D en las diferentes enfermedades dermatologicas, como el lupus eritematoso, la ictiosis, la dermatitis atopica, la hidrosadenitis supurativa, el acne, la alopecia areata y androgenetica, el melanoma y el cancer cutaneo no melanoma, asi como la relevancia como terapia adyuvante en pacientes en tratamiento cronico con corticoides. Acercamos al lector la informacion mas relevante y reciente de la relacion entre la vitamina D y las enfermedades de la piel, asi como la importancia de conocer los niveles de esta vitamina.

The administration of appropriate doses of active ingredients and excipients is crucial for achieving desired treatment outcomes in pediatric dermatology. A number of factors need to be considered, including the characteristics of the lesion, the patient, and the drug. An additional challenge in pediatric settings is the limited number of commercially available formulations suitable for use in children. Drug compounding, which is the preparation of medications tailored to the needs of individual patients, is a good alternative for pediatric populations for a number of reasons. Using a customized compound, the clinician can prescribe formulations that contain the optimal dose of the active ingredients within acceptable limits and the most suitable vehicle and formulation components. Compounding can also be used to combine several active ingredients in a single medication and even adapt the vehicle to the characteristics of the lesion and the needs of the patient. The pharmaceutical formulations described in this review are based on extensive clinical experience and can be customized to meet individual needs.

In recent years, the growing interest in the role played by vitamin D in skin disease has given rise to the publication of many studies of the relationship between this vitamin and certain skin conditions. As dermatologists, we need to understand, among other aspects, how vitamin D is synthesized and the main sources in humans, as well as plasma levels and the factors that can modify them. Of particular interest are the latest discoveries about the role of vitamin D in skin diseases such as lupus erythematosus, ichthyosis, atopic dermatitis, hidradenitis suppurativa, acne, alopecia areata, androgenetic alopecia, melanoma, and nonmelanoma skin cancer. Also of interest is the importance of vitamin D as adjuvant therapy in patients on long-term treatment with corticosteroids. In this review, we provide an overview of the most important and most recent information regarding the relationship between vitamin D and skin disease and discuss the importance of assessing individual vitamin D status and correcting deficiencies.