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Start Over Descriptor "Viral Envelope Proteins therapeutic use" Journal acta pharmaceutica zagreb croatia

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1. Development of a selective biopharmaceutical from Herpes simplex virus type 1 glycoproteins E and I for blocking antibody mediated neutralization of oncolytic viruses.

Author

Bucurescu S

Subjects
Animals, Antibodies, Viral immunology, Clinical Trials as Topic, Herpesvirus 1, Human, Humans, Neoplasms drug therapy, Oncolytic Viruses immunology, Viral Envelope Proteins immunology, Viral Envelope Proteins metabolism, Antibodies, Blocking immunology, Antibodies, Neutralizing immunology, Neoplasms therapy, Oncolytic Virotherapy, Oncolytic Viruses physiology, Viral Envelope Proteins therapeutic use
Abstract

Future cancer therapies will be molecular cures. They will correct, block or destroy cancer cells by targeting molecular changes that lead to carcinogenesis. Destroying cancer cells can be done using oncolytic viruses. By blocking antibody mediated neutralization of oncolytic viruses, Herpes simplex virus type 1 glycoproteins E and I could be used in the adjuvant treatment of cancer for improving the chances of oncolytic viruses to kill cancer cells in vivo.

Published
2010
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