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Objective-To quantitatively analyze modifications of the paratubal muscles in developing Wistar rats following nasal obstruction. Material and Methods-Twenty-four Wistar rats were used. Twelve were examined at 6, 8 and 12 weeks after birth and were considered normal controls. The nostrils of the remaining 12 rats were bilaterally obstructed by means of a synthetic resin 28 days after birth. The animals were sacrificed at either 2, 4 or 8 weeks after nostril occlusion. Serial sections were made in the dorsoventral plane and stained with hematoxylin-eosin. Four 5×5 μm[SUP2] areas, selected within the paratubal muscles, were histologically analyzed and the number of muscular fibers was counted manually. Results-The number of tensor veli palatini muscle fibers progressively decreased in the obstructed rats compared with age-matched normal controls and in those that had been obstructed for 4 and 8 weeks these reductions were statistically significant. Conclusion-The correct development of the paratubal muscles seems to be linked to physiological nasal breathing and is negatively affected by oral breathing. [ABSTRACT FROM AUTHOR]

Presents a letter to the editor of the periodical "Acta Oto-Laryngologica," responding to a critique on a paper about autoimmunity in sudden sensorineural hearing loss.