3 results
Search Results
2. Restoring speech perception with cochlear implants by spanning defective electrode contacts.
- Author
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Frijns, Johan H.M., Snel-Bongers, Jorien, Vellinga, Dirk, Schrage, Erik, Vanpoucke, Filiep J., and Briaire, Jeroen J.
- Subjects
SPEECH perception ,COCHLEAR implants ,ELECTRODES ,ARTIFICIAL implants ,RESEARCH funding ,STATISTICS ,T-test (Statistics) ,DATA analysis ,VISUAL analog scale ,DATA analysis software ,DESCRIPTIVE statistics - Abstract
Conclusion: Even with six defective contacts, spanning can largely restore speech perception with the HiRes120 speech processing strategy to the level supported by an intact electrode array. Moreover, the sound quality is not degraded. Objectives: Previous studies have demonstrated reduced speech perception scores (SPS) with defective contacts in HiRes 120. This study investigated whether replacing defective contacts by spanning, i.e. current steering on non-adjacent contacts, is able to restore speech recognition to the level supported by an intact electrode array. Methods: Ten adult cochlear implant recipients (HiRes90K, HiFocus1J) with experience with HiRes120 participated in this study. Three different defective electrode arrays were simulated (six separate defective contacts, three pairs or two triplets). The participants received three take-home strategies and were asked to evaluate the sound quality in five predefined listening conditions. After 3 weeks, SPS were evaluated with monosyllabic words in quiet and in speech-shaped background noise. Results: The participants rated the sound quality equal for all take-home strategies. SPS with background noise were equal for all conditions tested. However, SPS in quiet (85% phonemes correct on average with the full array) decreased significantly with increasing spanning distance, with a 3% decrease for each spanned contact. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF
3. High complication risk of salvage surgery after chemoradiation failures.
- Author
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Sewnaik, Aniel, Keereweer, Stijn, Al-Mamgani, Abrahim, Baatenburg de Jong, Robert J., Wieringa, Marjan H., Meeuwis, Cees A., and Kerrebijn, Jeroen D.F.
- Subjects
FISTULA ,CANCER chemotherapy ,LARYNGECTOMY ,LARYNGEAL tumors ,MEDICAL cooperation ,PHARYNX surgery ,PHARYNX tumors ,QUALITY of life ,QUESTIONNAIRES ,RESEARCH ,RETROSPECTIVE studies ,DESCRIPTIVE statistics ,DIAGNOSIS ,TUMOR treatment - Abstract
Conclusions: Although organ preservation can be achieved with chemoradiation protocols for laryngeal or pharyngeal cancers, salvage surgery is accompanied by high complication rates. Objectives: To determine the rate of complications associated with salvage surgery after chemoradiation for laryngeal and pharyngeal cancers. Methods: A multicenter retrospective study was performed of 24 patients treated with total laryngectomy combined with total or partial pharyngectomy between 1995 and 2004 who had previously been treated with chemoradiation. The main outcome measures were early and late complication rates. Quality of life analysis was determined by two questionnaires. Results: The complication rate after salvage surgery was 92% in the direct postoperative period. The most frequent complication was pharyngocutaneous fistula formation. Narrowing of the esophagus and tracheostoma were the most common late sequelae. The quality of life, measured at least 2 years after salvage surgery, showed a social dysfunctioning. [ABSTRACT FROM AUTHOR]
- Published
- 2012
- Full Text
- View/download PDF
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