1. Low 25-hydroxyvitamin D levels in postmenopausal female patients with benign paroxysmal positional vertigo.
- Author
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Han, Weiwei, Fan, Zhenyi, Zhou, Min, Guo, Xu, Yan, Wang, Lu, Xiaoxiong, Li, Li, Gu, Chengyao, Chen, Caijing, and Wu, Yunqin
- Subjects
OSTEOPENIA ,VITAMIN D deficiency ,BENIGN paroxysmal positional vertigo ,CHI-squared test ,CHINESE people ,CONFIDENCE intervals ,OSTEOPOROSIS ,VITAMIN D ,CONTROL groups ,DISEASE prevalence ,RETROSPECTIVE studies ,POSTMENOPAUSE ,DATA analysis software ,DESCRIPTIVE statistics ,ODDS ratio ,DIAGNOSIS - Abstract
Objective: Several studies have reported the association of benign paroxysmal positional vertigo (BPPV) with vitamin D deficiency. This study aimed to evaluate serum 25-hydroxy vitamin D (25 (OH) D) levels in native Chinese postmenopausal women with de novo idiopathic BPPV and to investigate the possible relationship between the occurrence of BPPV and low 25 (OH) D levels.Methods: This retrospective study comprised of 85 postmenopausal women with de novo idiopathic BPPV and 80 age-matched healthy controls. All subjects had bone mineral density (BMD) and serum 25 (OH) D levels measurements recorded, and the results were compared.Results: The prevalence of reduced BMD (T score <−1.0) was significantly higher in female patients with BPPV than in healthy controls (71.8% vs. 51.2%,p = .004). The mean serum 25 (OH) D levels were also significantly lower in female patients with BPPV than in healthy controls (19.1 ± 5.2 vs. 22.5 ± 5.8,p < .001). The regression analyses demonstrated that vitamin D deficiency was associated with BPPV with an odds ratio of 2.1 (95% confidence interval = 1.1-3.1,p = .031).Conclusion: Our study suggests that low 25 (OH) D may be a risk factor for BPPV in postmenopausal women. [ABSTRACT FROM AUTHOR]- Published
- 2018
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