1. Measurement of thickness of retinal nerve fiber layer by scanning laser polarimetry and high-pass resolution perimetry in patients with primary open-angle or normal-tension glaucoma
- Author
-
Shigeo Funaki, Haruki Abe, Motohiro Shirakashi, and Shoichi Sawaguchi
- Subjects
Male ,medicine.medical_specialty ,genetic structures ,Open angle glaucoma ,Nerve fiber layer ,Glaucoma ,Scanning laser polarimetry ,Retina ,chemistry.chemical_compound ,Nerve Fibers ,Ophthalmology ,Normal tension glaucoma ,Image Processing, Computer-Assisted ,medicine ,Humans ,In patient ,Observer Variation ,business.industry ,Lasers ,Optic Nerve ,Retinal ,Anatomy ,Middle Aged ,medicine.disease ,eye diseases ,medicine.anatomical_structure ,chemistry ,Visual Field Tests ,High-pass resolution perimetry ,Female ,sense organs ,Visual Fields ,business ,Glaucoma, Open-Angle - Abstract
Purpose: To evaluate the correlation between neural capacity, determined by high-pass resolution perimetry, and thickness of the retinal nerve fiber layer, evaluated by scanning laser polarimetry, in patients with primary open-angle glaucoma or normal-tension glaucoma. Methods: Thickness of the peripapillary retinal nerve fiber layer was measured by scanning laser polarimetry in 19 eyes of 19 patients with primary open-angle glaucoma and in 23 eyes of 23 patients with normal-tension glaucoma. There were no significant differences between the two groups in mean age, sex ratio, or mean neural capacity. Results: Neural capacity was significantly correlated with thickness of the retinal nerve fiber layer in all 42 eyes (r = 0.31, P = 0.0429). Neural capacity was significantly correlated with thickness of the retinal nerve fiber layer in the eyes of patients with primary open-angle glaucoma (r = 0.60, P = 0.0061), but not in the eyes of patients with normal-tension glaucoma (r = 0.04; P = 0.8522). Conclusion: The degree of correlation between neural capacity determined by high-pass resolution perimetry and thickness of the retinal nerve fiber layer measured by scanning laser polarimetry appeared to differ in patients with primary open-angle glaucoma vs those with normal-tension glaucoma.
- Published
- 2009