1. Stem cell transplantation therapy in Parkinson's disease.
- Author
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Mu-Hui Fu, Chia-Ling Li, Hsiu-Lien Lin, Pei-Chun Chen, Calkins, Marcus J., Yu-Fan Chang, Pei-Hsun Cheng, and Shang-Hsun Yang
- Subjects
STEM cell culture ,CELL culture - Abstract
Ineffective therapeutic treatments and inadequate repair ability in the central nervous system are disturbing problems for several neurological diseases. Fortunately, the development of clinically applicable populations of stem cells has provided an avenue to overcome the failure of endogenous repair systems and substitute new cells into the damaged brain. However, there are still several existing obstacles to translating into clinical application. Here we review the stem-cell based therapies for Parkinson's disease and discuss the potential advantages and drawbacks. We hope this review may provide suggestions for viable strategies to overcome the current technical and biological issues associated with the application of stem cells in Parkinson's disease. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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