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Your search keyword '"Hawkins, Cynthia"' showing total 2 results
Start Over Author "Hawkins, Cynthia" Topic braf genes Journal acta neuropathologica
2 results on '"Hawkins, Cynthia"'

1. cIMPACT-NOW update 4: diffuse gliomas characterized by MYB, MYBL1, or FGFR1 alterations or BRAFV600E mutation.

Author

Ellison, David W., Hawkins, Cynthia, Jones, David T. W., Pfister, Stefan M., Onar-Thomas, Arzu, Reifenberger, Guido, and Louis, David N.

Subjects
*GLIOMAS, *BRAF genes, *MYB gene
Abstract

The article discusses the IDH-wt?H3-wt diffuse gliomas arising mainly in middle-aged adults and grading for it by World Health Organization (WHO) which is characterized by BRAF mutation, FGFR alteration or MYB or MYBLI rearrangement.

Published
2019
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2. BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology.

Author

Shankar, Ganesh, Lelic, Nina, Gill, Corey, Thorner, Aaron, Hummelen, Paul, Wisoff, Jeffrey, Loeffler, Jay, Brastianos, Priscilla, Shin, John, Borges, Lawrence, Butler, William, Zagzag, David, Brody, Rachel, Duhaime, Ann-Christine, Taylor, Michael, Hawkins, Cynthia, Louis, David, Cahill, Daniel, Curry, William, and Meyerson, Matthew

Subjects
BRAF genes, SUPRATENTORIAL brain tumors, GLIOMAS, MOLECULAR oncology, CHROMOSOME abnormalities
Abstract

The article discusses a study related to supratentorial gliomas which reveals discrete genomic alterations to discriminate discriminate pilocytic astrocytomas, diffuse gliomas, and glioblastoma. Topics discussed includes co-deletion of chromosomes not revealed by loss of heterozygosity analysis for variant allele frequency, assess for the changes by transcriptional analysis of spinal cord astrocytomas, and success in BRAF-mutant cancer types with the BRAFâ€MEK inhibitors.

Published
2016
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