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Start Over Descriptor "CPP optimum" Journal acta neurochirurgica
2 results on '"CPP optimum"'

1. Optimal cerebral perfusion pressure via transcranial Doppler in TBI: application of robotic technology.

Author

Zeiler, Frederick A., Czosnyka, Marek, and Smielewski, Peter

Subjects
*CEREBRAL hemispheres, *PERFUSION, *TRANSCRANIAL Doppler ultrasonography, *SURGICAL robots, *INTRACRANIAL pressure, *BRAIN injuries
Abstract

Individualized cerebral perfusion pressure (CPP) targets may be derived via assessing the minimum of the parabolic relationship between an index of cerebrovascular reactivity and CPP. This minimum is termed the optimal CPP (CPPopt), and literature suggests that the further away CPP is from CPPopt, the worse is clinical outcome in adult traumatic brain injury (TBI). Typically, CPPopt estimation is based on intracranial pressure (ICP)-derived cerebrovascular reactivity indices, given ICP is commonly measured and provides continuous long duration data streams. The goal of this study is to describe for the first time the application of robotic transcranial Doppler (TCD) and the feasibility of determining CPPopt based on TCD autoregulation indices. [ABSTRACT FROM AUTHOR]

Published
2018
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2. Optimal cerebral perfusion pressure via transcranial Doppler in TBI: application of robotic technology

Author

Marek Czosnyka, Peter Smielewski, Frederick A. Zeiler, Zeiler, Frederick A [0000-0003-1737-0510], and Apollo - University of Cambridge Repository

Subjects
medicine.medical_specialty, Neurology, Traumatic brain injury, 03 medical and health sciences, 0302 clinical medicine, Cerebrovascular reactivity, Internal medicine, TBI, Brain Injuries, Traumatic, medicine, Humans, Autoregulation, Cerebral perfusion pressure, Neuroradiology, Intracranial pressure, business.industry, musculoskeletal, neural, and ocular physiology, TCD, Ultrasonography, Doppler, 030208 emergency & critical care medicine, Robotics, medicine.disease, Transcranial Doppler, Cerebrovascular Circulation, Cardiology, Case Report - Brain trauma, Surgery, CPP optimum, Neurology (clinical), business, 030217 neurology & neurosurgery, Robotic transcranial Doppler
Abstract

Individualized cerebral perfusion pressure (CPP) targets may be derived via assessing the minimum of the parabolic relationship between an index of cerebrovascular reactivity and CPP. This minimum is termed the optimal CPP (CPPopt), and literature suggests that the further away CPP is from CPPopt, the worse is clinical outcome in adult traumatic brain injury (TBI). Typically, CPPopt estimation is based on intracranial pressure (ICP)-derived cerebrovascular reactivity indices, given ICP is commonly measured and provides continuous long duration data streams. The goal of this study is to describe for the first time the application of robotic transcranial Doppler (TCD) and the feasibility of determining CPPopt based on TCD autoregulation indices. Electronic supplementary material The online version of this article (10.1007/s00701-018-3687-5) contains supplementary material, which is available to authorized users.

Published
2018

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